Porphyromonas Denticanis-Gulae-Salivosa BacterinThis page contains information on Porphyromonas Denticanis-Gulae-Salivosa Bacterin for veterinary use.
The information provided typically includes the following:
- Porphyromonas Denticanis-Gulae-Salivosa Bacterin Indications
- Warnings and cautions for Porphyromonas Denticanis-Gulae-Salivosa Bacterin
- Direction and dosage information for Porphyromonas Denticanis-Gulae-Salivosa Bacterin
Porphyromonas Denticanis-gulae-salivosa BacterinThis treatment applies to the following species:
Notice: This Product License Is Conditional. Efficacy And/or Potency Of This Product Have Not Been Fully Demonstrated, Consultation With A Veterinarian Is Recommended.
For use in dogs only
Product DescriptionPorphyromonas Denticanis-Gulae-Salivosa Bacterin is for vaccination of healthy dogs as an aid in preventing periodontitis, as demonstrated by a reduction in bone changes (bone lysis/sclerosis) associated with Porphyromonas denticanis, P. gulae, and P. salivosa. This vaccine is a liquid preparation of inactivated Porphyromonas bacterium.
Disease DescriptionPeriodontal disease is a progressive, on-going, destructive disease that affects 85% of dogs over 3 years of age.1 The majority of dogs and cats greater than 3 years of age require some form of intervention or treatment.2 Periodontal disease encompasses the inflammation, infection and subsequent destruction of the periodontium or the supporting structures of the tooth. It has traditionally been divided into two general categories, gingivitis and periodontitis, based upon whether attachment loss has occurred. Gingivitis is the presence of gingival inflammation without loss of connective tissue attachment (no pathological periodontal pocket).3 Periodontitis can be defined as gingival inflammation at sites where there has also been loss of attached gingiva and destruction of the periodontal ligament. This damage to the periodontal ligament leads to an irreversible destruction of underlying alveolar bone. Periodontal disease is a continuum of stages beginning with inflammation of the free gingival margin (gingivitis) and resulting in advanced periodontitis and tooth loss.
Safety And EfficacySafety of Porphyromonas Denticanis-Gulae-Salivosa Bacterin was established in trials involving animals from multiple geographic locations. Healthy dogs as young as 7 weeks of age were vaccinated according to label directions. No significant adverse events were observed in any animals during the study period. Efficacy studies and potency test validation are in progress. A reasonable expectation of efficacy has been demonstrated in dogs 8 months of age. Duration of immunity for this product has not been evaluated.
General Directions: Vaccination of healthy dogs is recommended. Shake well. Aseptically administer 1 mL subcutaneously.
Primary Vaccination: Healthy dogs should receive 2 doses administered 3 weeks apart.
Revaccination: Duration of immunity for this product has not been evaluated; consultation with a veterinarian is recommended.
Store at 2°-7°C. Prolonged exposure to higher temperatures may adversely affect potency. Do not freeze.
Use entire contents when first opened.
Sterilized syringes and needles should be used to administer this vaccine.
Transient lethargy and soreness may occur following vaccination.
In case of anaphylaxis, administer epinephrine or equivalent.
1. Beard G, Emily P, Milligan & Williams C: American Animal Hospital Association, Veterinary Dentistry, Course I, 1989.
2. Gorrel C: Radiographic Evaluation. Vet Clin of N Am. Small Animal Practice. 28(5): 1089-1110.
3. Armitage G et al: Academy Report: Diagnosis of Periodontal Diseases. J Periodontology 74: 1237-1247, 2003.
Technical inquiries should be directed to Pfizer Animal Health Veterinary Services, (800) 366-5288 (USA), (800) 461-0917 (Canada).
For veterinary use only
U.S. Veterinary License No. 189
Pfizer Animal Health, Exton, PA 19341, USA
Div. of Pfizer Inc, NY, NY 10017
Presentation25 x 1 dose.
PFIZER ANIMAL HEALTH
235 E. 42ND ST., NEW YORK, NY, 10017
|Customer Service:||800-733-5500 and 800-793-0596|
|Veterinary Medical Investigations & Product Support:||800-366-5288|
|Technical Services (USA):||800-366-5288|
|Every effort has been made to ensure the accuracy of the Porphyromonas Denticanis-Gulae-Salivosa Bacterin information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.|
Copyright © 2013 North American Compendiums. Updated: 2013-09-18