Penmed (Canada)

Description

PENMED is an antibacterial agent effective against a wide variety of pathogenic organisms. It is the water-insoluble salt of benzyl penicillin containing one molecule of penicillin G combined with one molecule of procaine base.

PENMED, aqueous suspension is a sterile free-flowing product prepared from penicillin G procaine crystalline. Each mL contains 300,000 I.U. of penicillin G procaine.

Penmed Indications And Conta-indications

Clinical results following administration of penicillin G procaine, aqueous suspension are similar to those observed with other repository forms of penicillin. It may be used, therefore, in those cases in which penicillin or repository forms of penicillin procaine are indicated.

PENMED, aqueous suspension is indicated in the treatment of infections caused by penicillin-sensitive organisms such as:

Cattle

Actinomycosis; blackleg; calf diphtheria; foot rot; joint infections; leptospirosis; malignant edema; mastitis; metritis; navel infections; pneumonia; pyelonephritis; shipping fever complex; tetanus (in early stages, with antitoxin); wound infections, and other infections caused by or associated with penicillin-sensitive organisms.

Swine

Erysipelas; joint infections; leptospirosis; mastitis; metritis; navel infections; pneumonia; wound infections, and other infections caused by or associated with penicillin- sensitive organisms.

Sheep

Blackleg; joint infections; mastitis; metritis; navel infections; pneumonia; wound infections, and other infections caused by or associated with penicillin-sensitive organisms.

Horses

Bacterial complications associated with influenza; joint infections; metritis; navel infections; pneumonia; strangles; tetanus (in early stages, with antitoxin); wound infections, and other infections caused by or associated with penicillin-sensitive organisms.

Small Animals (dogs, Cats, Mink, Rabbits, Foxes)

Bacterial infections associated with viral diseases; bronchitis; middle ear infections; leptospirosis; pneumonia; snuffles; sore hocks, tetanus (in early stages, with antitoxin); tracheitis; wound infections, and other infections caused by or associated with penicillin-sensitive organisms.

The use of PENMED, aqueous suspension is not indicated in infections due to gram-negative organisms or viruses.

Penmed Cautions

Sensitivity to penicillin or to procaine. FOR INTRAMUSCULAR USE ONLY.

Allergic reactions (urticaria, contact dermatitis, serum-sickness-like syndromes) are observed occasionally; however, and probably are the result of individual hypersensitivity. This hypersensitivity may be either pre-existent or may develop following the use of penicillin. In urticaria, caused by penicillin, the use of antihistamine compounds has been successful in alleviating the symptoms in many cases. Mild reactions and those responding to the usual treatment of such conditions are not contraindications to the further administration of penicillin. Severe uncontrollable reactions require discontinuance of penicillin therapy. In case of an anaphylactic reaction, administer epinephrine immediately.

In suckling and fattening pigs, administration of procaine penicillin G will cause occasional transient pyrexia, vomiting, shivering and incoordination. Abortions have also been reported in pregnant sows and gilts. If the condition has not changed in 36-48 hours, the treatment should be re-evaluated and a veterinarian should be consulted.

Warnings

Milk taken from treated animals within 72 hours after the latest treatment must not be used in food. Treated animals must not be slaughtered for use in food for at least 5 days after the latest treatment with this drug. Do not administer to horses that are to be slaughtered for use in food.

Administration

Shake Well Before Using. Only The Intramuscular Route Is Recommended For The Administration Of Penmed, Aqueous Suspension.

daily Dosage

Body Weight	DOSAGE
Cattle	6,670 I.U. per kg of body weight
45 to 135 kg	1 to 3 mL	Use 16 or 18 gauge, 2.5 or 3.5 cm needle.
135 to 360 kg	3 to 8 mL
360 kg or over	8 to 10 mL

Swine	12,000-18,000 I.U. per kg of body weight
2 to 5 kg	0.25 mL	Use 18 gauge, 2.5 cm needle.
5 to 25 kg	0.25 to 1.50 mL
25 to 50 kg	1.50 to 2 mL
50 kg or over	2 to 5 mL

Sheep	12,000-18,000 I.U. per kg of body weight
2 to 5 kg	0.25 mL	Use 18 gauge, 2.5 cm needle.
5 to 10 kg	0.25 to 0.75 mL
10 to 25 kg	0.75 to 1.50 mL
25 to 50 kg	1.50 to 2 mL
50 kg or over	2 to 4 mL

Horses	2,610-6,666 I.U. per kg of body weight
Up to 225 kg	2 to 5 mL	Use 16 or 18 gauge, 3.5 or 5 cm needle.
225 to 450 kg	5 to 10 mL
450 kg or over	10 to 20 mL

Small Animals (dogs, Cats, Minks, Rabbits, Foxes)	37,500 I.U. per kg of body weight
1 to 2 kg	0.125 to 0.25 mL	Use 20 gauge, 2 or 2.5 cm needle.
2 to 5 kg	0.25 to 0.50 mL
5 to 10 kg	0.50 to 0.75 mL
10 to 25 kg	0.75 to 1 mL
25 kg or over	1 to 2 mL

Knowledge of exact body weight is important to ensure an appropriate dosage. Administer once a day or as recommended by a veterinarian. Continue treatment for 1 or 2 days after the symptoms disappear.

Storage Condition

Store below 15°C and keep from freezing.

Net Contents: 250 mL

Nac No.

12200140