Papillomune

Manufacturer: Biomune

Bovine Wart Vaccine, Killed Virus

U.s. Vet. Lic. No.

368

Contents

PAPILLOMUNE™ contains a standardized, inactivated concentration of virus-laden tissue extract derived from bovine papillomas. The antigenic concentration contained in PAPILLOMUNE™ exceeds the minimum volume set by USDA and is labeled for a uniform 10 mL dose. PAPILLOMUNE™ is a uniformly clear, homogenous suspension that is easily syringeable.

Papillomune Indications

PAPILLOMUNE™ is indicated for use as an aid in the prevention of viral warts in cattle. Vaccinate only healthy animals.

Papillomune Dosage And Administration

Shake well before using. Administer 10 mL subcutaneously in two sites on the animal (5 mL each) using aseptic technique. Repeat dose in 3-5 weeks. Because the papilloma virus is so environmentally stable, many experienced bovine practitioners suggest continuation of the vaccination regime for at least one year after the last warts have been observed in a herd.

Precaution(s)

Use entire contents when first opened. Store in the dark at 35°-45°F (2°-7°C).

Papillomune Caution(s)

Vaccinate only healthy animals. This vaccine is a tissue derived extract. In case of anaphylactic reaction use epinephrine or equivalent.

This vaccine has been carefully produced and has undergone purity and safety tests to meet Biomune's requirements and USDA regulations.

Warning(s)

Do not vaccinate within 21 days of slaughter.

Discussion

Field testing of several hundred animals demonstrated PAPILLOMUNE™ to be safe, with no adverse reactions. Injection site swelling was minimal and of short duration.

In animals destined for the show-ring, and in seedstock cattle, warts (papillomas) can seriously impair the aesthetic, and ultimately the economic value of the animal. Benign, self limiting tumors, warts in cattle are caused by bovine papilloma virus. The virus replicates within the wart tissue with a great deal of the infective virus residing near the surface. When affected animals rub against fences, stanchions or other objects, they may transfer infective virus to the object leaving others in the herd vulnerable to infection should they receive skin abrasions from these objects.

Surgical instruments, needles, tattoo pliers and other instruments have also been suspected sources of virus spread between animals. While usually appearing on the head, neck and shoulders, warts can occur anywhere on the animal's body, including mucous membranes of the reproductive tract. Surgical removal or chemical treatment are often unacceptable to owners and may stimulate regrowth and spread of warts.

References

Available upon request.

Presentation

1 dose (10 mL) and 5 dose (50 mL) vials.

Nac No.

11290240