Nitrofurazone Soluble Dressing (Canada)This page contains information on Nitrofurazone Soluble Dressing for veterinary use.
The information provided typically includes the following:
- Nitrofurazone Soluble Dressing Indications
- Warnings and cautions for Nitrofurazone Soluble Dressing
- Direction and dosage information for Nitrofurazone Soluble Dressing
Nitrofurazone Soluble DressingThis treatment applies to the following species:
Nitrofurazone Ointment USP 0.2% w/w
Veterinary Use Only
GENERAL INFORMATION: Nitrofurazone is a synthetic nitrofuran with a broad antibacterial spectrum. It effectively destroys most bacteria commonly causing surface infection, including many that have become antibiotic-resistant. It acts by inhibiting enzymes necessary for carbohydrate metabolism in bacteria. This action occurs in both the aerobic and anaerobic cycles of carbohydrate metabolism, explaining its bactericidal effect in aerobic, anaerobic and anaerobic facultative bacteria. For best effect it should be applied for at least 24 hours. It retains its antibacterial activity in blood, serum and pus; phagocytosis is not inhibited nor does it interfere with healing. Five to seven days of topical therapy will eradicate most infections. If desired, any bland agent or protective dressing can be used for the remainder of the healing period. Therapy can be repeated if the infection reoccurs.
WarningsKEEP OUT OF REACH OF CHILDREN. FEDERAL LAW PROHIBITS THE ADMINISTRATION OF THIS PREPARATION TO ANIMALS THAT PRODUCE FOOD OR THAT ARE INTENDED FOR CONSUMPTION AS FOOD. THIS DRUG IS NOT TO BE ADMINISTERED TO HORSES THAT ARE TO BE SLAUGHTERED FOR USE IN FOOD.
SENSITIZATION: The incidence of irritation or sensitization has been low. This incidence is approximately 2%, including irritation and sensitivity incurred in treating chronic stasis ulcers, notoriously easily irritated by any agent. In surgical cases, as in burns, irritation and sensitivity are seldom seen, the incidence not exceeding 1%. To minimize any adverse effect, the veterinarian should remove the medication by irrigation at the first sign of irritation. It may be helpful, in chronic stasis ulcers, to protect the easily irritated skin surrounding them with zinc oxide ointment, and to confine the drug to the lesion itself. Nitrofurazone Soluble Dressing does not, of course, replace surgical procedures when these are indicated, however it is a useful adjunct.
Nitrofurazone 0.2% w/w dissolved in a water-soluble base of polyethylene glycols.
INDICATIONS: Nitrofurazone Soluble Dressing is indicated as an aid in the prophylaxis and treatment of superficial bacterial infections sensitive to nitrofurazone, associated with wounds, burns, cutaneous ulcers, skin grafts and donor sites and for the treatment of pyodermas in dogs and horses.
Dosage and Administration
Wounds and Burns: Apply directly to the lesions with a spatula, or first place on gauze. Reapply once daily or once weekly, depending on the preferred dressing technique. To avoid adherence by drying of exudates, impregnated gauze may be covered by waxed paper or petroleum gauze.
Pyodermas: Apply several times daily with or without a gauze dressing. Use only on abscesses and carbuncles following incision or rupture.
Ulcers: Varicose and decubitus ulcers may be treated as are wounds and lesions.
However, in chronic cases, it is advisable to protect the abnormally sensitive skin about the lesion with zinc oxide ointment or paste. Restricting application to five (5) to seven (7) days where feasible, minimizes irritation and sensitization. It is effective only when bacterial infection is responsible for lack of healing.
Skin Grafts: The dressing is used both to prepare burns and other lesions for grafting, and postoperatively as a prophylactic measure. By rapid eradication of the infection, it can produce clean, firm granulation tissue. Because it is water-soluble and has negligible tissue toxicity, it does not interfere with successful takes. To avoid adherence on the bandage, Nitrofurazone Soluble Dressing impregnated gauze may be covered by waxed paper or petroleum gauze. This may be left intact for five (5) to seven (7) days. Flushing the gauze with saline facilitates removal.
CAUTIONS: In case of deep or puncture wounds or serious burns, consult a veterinarian. If redness, irritation or swelling persists or increases, discontinue use and consult a veterinarian.
StorageStore between 15-30°C. Avoid freezing. The discoloration of product by light does not indicate loss of efficacy.
Partnar Animal Health Inc., 14057 Ilderton Road, Ilderton, Ontario, Canada N0M 2A0
NAC No.: 12890101
14057 ILDERTON ROAD, ILDERTON, ON, N0M 2A0
|Every effort has been made to ensure the accuracy of the Nitrofurazone Soluble Dressing information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.|
Copyright © 2014 North American Compendiums. Updated: 2014-09-05