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Neomycin Oral Solution

This page contains information on Neomycin Oral Solution for veterinary use.
The information provided typically includes the following:
  • Neomycin Oral Solution Indications
  • Warnings and cautions for Neomycin Oral Solution
  • Direction and dosage information for Neomycin Oral Solution

Neomycin Oral Solution

This treatment applies to the following species:
Manufacturer: Durvet



ANADA 200-379, Approved by FDA



Indicated for the treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin sulfate in cattle, swine, sheep and goats.

Restricted Drug-Use Only As Directed (California)

For Oral Use in Animals only

Dosage and Administration

Administer to cattle, swine, sheep and goats at a dose of 10 mg neomycin sulfate per pound of body weight in divided doses for a maximum of 14 days.

Dosage Schedule for Treatment of Colibacillosis:

Pounds of Body Weight

Amount of Neomycin Oral Solution Per Day in Divided Doses

25 lb

1.2 mL (1/4 tsp*)

50 lb

2.5 mL (1/2 tsp*)

100 lb

5 mL (1 tsp*)

300 lb

15 mL (1 tbsp*)

591.5 lb

29.5 mL (1 fl oz)

Neomycin Solution may be given undiluted or diluted with water.

Herd Treatment: Each 473 mL (16 Fl Oz) bottle will treat 9,600 pounds body weight. Each 3.785 L (1 Gal) bottle will treat 76,800 pounds body weight. Therefore, estimate the total number of pounds body weight of the animals to be treated and administer one (1) fluid ounce for each 600 pounds. The product should be added to the amount of drinking water to be consumed in 12-24 hours. Provide medicated water as the sole source of water each day until consumed, followed by non-medicated water as required. Fresh medicated water should be prepared each day.

Individual Animal Treatment: To provide 10 mg neomycin sulfate per pound of body weight, mix one (1) teaspoon in water or milk for each 100 pounds body weight. Administer daily either as a drench in divided dosages or in the drinking water to be consumed in 12-24 hours.

Neomycin Oral Solution Caution

To administer the stated dosage, the concentration of neomycin required in medicated water must be adjusted to compensate for variation in age and weight of animal, the nature and severity of disease signs, and environmental temperature and humidity, each of which affects water consumption.

Contains per mL: neomycin sulfate 200 mg equivalent to 140 mg neomycin

If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. If symptoms such as fever, depression, or going off feed develop, oral neomycin is not indicated as the sole treatment since systemic levels of neomycin are not obtained due to low absorption from the gastrointestinal tract.

Important: Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 14 consecutive days. Animals not drinking or eating should be treated individually by drench.

Residue Warnings: Not for human use. Keep out of reach of children. Discontinue treatment prior to slaughter by at least the number of days listed below for appropriate species:

Cattle - 1 day, Sheep - 2 days, Swine and Goats - 3 days.

A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.

A milk discard period has not been established for this product in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older.

Use of more than one product containing Neomycin or failure to follow withdrawal times may result in illegal drug residues.

Store at controlled room temperature 20° to 25°C (68 to 77° F) (see USP).

* Teaspoon (tsp) / Tablespoon (tbsp) is equal to U.S. Standard Measure.

ANADA#: 200-379 Approved by F.D.A.

Manufactured for DURVET, INC., Blue Springs, Missouri 64014





473 mL (16 Fl Oz)


N-1050-05 Rev. 9-07

3.785 L (1 Gal)


N-1050-07 Rev. 9-07

NAC No.: 10841173

Telephone:   816-229-9101
Toll-Free:   800-821-5570
Fax:   816-224-3080
Website:   www.durvet.com
Email:   info@durvet.com
Every effort has been made to ensure the accuracy of the Neomycin Oral Solution information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2014 North American Compendiums. Updated: 2014-04-11