MGA 500 Liquid Premix

Manufacturer: Zoetis

(type A Medicated Article)

Heifers Fed In Confinement For Slaughter

For Increased Rate of Weight Gain, Improved Feed Efficiency and Suppression of Estrus (Heat).

Heifers Intended For Breeding

For Suppression of Estrus (Heat).

Each Pound Contains

Active Drug Ingredient
Melengestrol Acetate (as melengestrol acetate and its propylene glycol ketal)	500 mg
Inactive Ingredient
Propylene Glycol, U.S.P.	99.89%

Precautions

For manufacturing, processing, or repacking. To be mixed with feed prior to animal use. Use only as directed. Excessive contact with skin should be avoided. Destroy empty container. Do not reuse.

Store At Room Temperature

NADA #39-402, Approved by FDA

Directions For Use

Heifers Fed In Confinement For Slaughter

MGA 500 Liquid Premix (Type A Medicated Article) should be thoroughly mixed in liquid Type C medicated feed which must be fed at 0.5 to 2.0 pounds per head daily to provide 0.25 to 0.5 mg of melengestrol acetate per head per day. Average daily intakes approximating the middle of this range provide the most optimal and economical improvements in rate of gain and feed utilization. Constant daily intakes of 0.35 to 0.50 mg per head per day give a high degree of estrus suppression. Levels of 0.25 to 0.35 mg provide a lower but still effective degree of estrus suppression.

Heifers Intended For Breeding

MGA 500 Liquid Premix (Type A Medicated Article) should be thoroughly mixed in the supplement to provide 0.5 mg of melengestrol acetate per head per day.

Warnings

Not for human use. Restricted Drug (California)-Use Only As Directed

Precautions: Not Effective In Steers And Spayed Heifers.

Heifers Fed In Confinement For Slaughter

Withdrawal periods of three to five days or more should be avoided to prevent the possibility that the heifers may come into estrus (heat) at loading time.

Heifers Intended For Breeding

Do not exceed 24 days of feeding of melengestrol acetate to heifers intended for breeding. A reduced conception rate can be expected if heifers are bred at estruses observed within 1 to 12 days after withdrawal of melengestrol acetate, whereas heifers bred at subsequent observed estruses are expected to have normal conception rates.

Mixing Directions

Liquid Type B and C medicated feeds containing melengestrol acetate must have a pH of 4.0 to 8.0 and their labels must bear appropriate mixing directions. Mixing directions for liquid Type B or C feeds stored in recirculation tank systems are: “Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents from the bottom of the tank to the top. Recirculate daily, as directed in this paragraph even when the Type B (or C) feed is not used.” Mixing directions for liquid Type B and C feeds stored in mechanical, air or other agitation-type tank systems are: “Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily, as directed in this paragraph, even when the Type B (or C) feed is not used.”

Intermediate premixes should not be made from MGA 500 Liquid Premix (Type A Medicated Article) except as a part of a continuous mixing operation to make a complete liquid Type B or Type C medicated feed.

Thoroughly mix 0.5 to 4 pounds of MGA 500 Liquid Premix (Type A Medicated Article) per ton of a non-medicated feed to prepare a Type C medicated feed containing 0.25 to 2.0 grams of melengestrol acetate per ton. The following Table may be used as a guide in determining the amount of MGA 500 Liquid Premix (Type A Medicated Article) to be added to prepare a ton of Type C medicated feed.

Amount Of Type C Feed Fed (lb/head/day)	Melengestrol Acetate (mg/head/day)	Mga 500 Liquid Premix Per Ton Of Type C Feed
		When Added By Weight (lb)	When Added By Volume (ml)
0.5	0.25	2.00	876
0.5	0.30	2.40	1051
0.5	0.35	2.80	1226
0.5	0.40	3.20	1402
0.5	0.45	3.60	1577
0.5	0.50	4.00	1752
1.0	0.25	1.00	438
1.0	0.30	1.20	526
1.0	0.35	1.40	613
1.0	0.40	1.60	701
1.0	0.45	1.80	788
1.0	0.50	2.00	876
1.5	0.25	0.66	289
1.5	0.30	0.80	350
1.5	0.35	0.93	407
1.5	0.40	1.07	469
1.5	0.45	1.20	526
1.5	0.50	1.33	582
2.0	0.25	0.50	219
2.0	0.30	0.60	263
2.0	0.35	0.70	307
2.0	0.40	0.80	350
2.0	0.45	0.90	394
2.0	0.50	1.00	438

Type B medicated feed containing 4 to 10 grams melengestrol acetate per ton may be manufactured by thoroughly mixing 8 to 20 lbs of MGA 500 Liquid Premix with 1992 to 1980 lbs of non-medicated feed. Labeling for such Type B feed shall contain directions for manufacturing Type C medicated feeds containing 0.25 to 2.0 grams melengestrol acetate per ton (0.125 to 1.0 mg/lb). The Type C medicated feed, containing melengestrol acetate, must be top dressed on grain or roughage or mixed with a complete ration at the rate of 0.5 to 2.0 pounds per head per day.

Good manufacturing practice regulations must be adhered to in manufacturing feeds containing MGA 500.

Distributed by: Pharmacia & Upjohn Company, Division of Pfizer Inc, New York, NY 10017

Net Weight
40 Pounds (18 kg) (4.627gal [17.5 L])	1459000 813 931 410 0547-01

Nac No.

10490334