Metacam 20 mg/mL Solution for Injection (Canada)

This page contains information on Metacam 20 mg/mL Solution for Injection for veterinary use.
The information provided typically includes the following:
  • Metacam 20 mg/mL Solution for Injection Indications
  • Warnings and cautions for Metacam 20 mg/mL Solution for Injection
  • Direction and dosage information for Metacam 20 mg/mL Solution for Injection

Metacam 20 mg/mL Solution for Injection

This treatment applies to the following species:
Manufacturer: Boehringer

Meloxicam 20 mg/mL

Sterile

Veterinary Use Only

DIN 02330059

Each mL contains 20 mg meloxicam and 150 mg ethanol, as preservative.

Therapeutic Classification: Nonsteroidal anti-inflammatory drug (NSAID).

Metacam 20 mg/mL Solution for Injection Indications

Cattle: As an aid in improving appetite and weight gains when administered at the onset of diarrhoea, in combination with oral rehydration therapy, in calves over one week of age. For relief of pain following de-budding of horn buds in calves less than 3 months of age. For the symptomatic treatment of inflammation and pain associated with acute clinical mastitis.

Swine: For use in non-infectious locomotor disorders to reduce the symptoms of lameness and inflammation.

Dosage and Administration

Cattle: Single subcutaneous or intravenous injection of 0.5 mg meloxicam/kg body weight (2.5 mL/100 kg).

Swine: Single intramuscular injection at a dosage of 0.4 mg meloxicam/kg body weight (2.0 mL/100 kg). If required, a second administration of meloxicam can be given after 24 hours.

Contraindications

Do not use in animals suffering from gastrointestinal disorders such as irritation and hemorrhage, impaired hepatic, cardiac or renal function and hemorrhagic disorders or where there is individual hypersensitivity to the product.

Do not administer concurrently with steroidal, other nonsteroidal anti-inflammatory drugs or with anti-coagulant agents.

Concomitant use of NSAIDs with aminoglycoside antimicrobials in very young animals may result in renal toxicity.

Cautions: Do not use in bulls or boars intended for breeding. Avoid use in very severely dehydrated, hypovolaemic or hypotensive animals which require parenteral rehydration, as there may be a potential risk of increased renal toxicity.

Use of anti-inflammatories in very young or debilitated animals may involve additional risk.

The safety of meloxicam in breeding and

pregnant sows has not been fully evaluated.

Available data suggest that meloxicam has no harmful effects in the second and third trimester of pregnancy. However the potential effects of meloxicam on imminent parturition have not been evaluated. This product can be used in lactating sows.

Warnings

Cattle: Treated animals must not be slaughtered for use in food for at least 20 days after the latest treatment with this drug. Milk taken from treated animals during treatment and within 96 hours after the latest treatment with this drug must not be used in food. Do not use in calves to be processed for veal as a withdrawal period has not been established for pre-ruminating calves.

Swine: Treated animals must not be slaughtered for use in food for at least 5 days after the latest treatment with this drug.

Keep out of reach of children.

Adverse Reactions

Transient, slight injection site swellings may occasionally be seen following subcutaneous injection and intravenous injection.

In very rare cases, anaphylactoid reactions may occur and should be treated symptomatically.

Pharmacology

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic and anti-pyretic properties. Meloxicam also has anti-endotoxic properties because it has been shown to inhibit production of thromboxane B2 induced by E. coli endotoxin administration in calves.

Toxicology: The acute oral toxicity (LD50) of meloxicam assessed in rats, mini-pigs, mice and rabbits was >80 mg/kg, 1600 mg/kg, 470 mg/kg and 320 mg/kg, respectively. Repeated dose toxicity studies in rats, mice and mini-pigs demonstrated that the primary target organs for toxicity were the gastrointestinal tract (pyloric, duodenal and small intestine ulceration) and kidneys (scarring, necrosis and pyelonephritis).

Storage

Store at or below 25°C. Keep from freezing.

Presentation: Metacam 20 mg/mL Solution for Injection is available in 20 mL, 50 mL and 100 mL multi-dose vials.

Metacam® is a registered trademark of Boehringer Ingelheim Vetmedica GmbH, used under license.

Boehringer Ingelheim (Canada) Ltd., 5180 South Service Road, Burlington, Ontario L7L 5H4.

Revised: 10-2013

40793/005

NAC No.: 1230067.5

BOEHRINGER INGELHEIM (CANADA) LTD.
5180 SOUTH SERVICE ROAD, BURLINGTON, ON, L7L 5H4
Customer Care No.:   800-567-1885
Technical Services No.:   1-877-565-5501
Website:   www.boehringer-ingelheim.ca
Every effort has been made to ensure the accuracy of the Metacam 20 mg/mL Solution for Injection information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2014 North American Compendiums. Updated: 2014-09-05

(web2)