Lidocaine HCl 2% (Canada)

Manufacturer: Pfizer

Lidocaine HCl and Epinephrine Injection, USP

Sterile

DIN 00712876

Veterinary Use Only

Active Ingredients

Lidocaine HCl	20 mg/mL
Epinephrine	0.01 mg/mL

Preservative

Methylparaben

0.1% w/v

Description

Lidocaine HCl with Epinephrine is a local anesthetic agent which can be used for infiltration or conduction (nerve blocking) anesthesia. It is twice as potent as procaine hydrochloride and produces more prompt, longer lasting and more extensive anesthesia than the latter preparation.

Lidocaine HCl is stable and non irritating and although it is highly effective without an accompanying vaso-constrictor, epinephrine (1:100,000) has been included to lengthen the duration of anesthesia.

Lidocaine HCl 2% Indication

When Lidocaine HCl is used for infiltration anesthesia, as small a volume as possible should be used. Infiltration anesthesia can be obtained through subcutaneous or intramuscular routes of administration. Administer the injection slowly. Dosage depends on the size of the animal and the area to be anesthetized.

HORSES: Infiltration Anesthesia - 2 to 50 mL. Subcutaneously or intramuscularly. For suturing wounds, minor surgery and therapeutic cautery.

Regional Nerve Blocks

Infra Orbital Nerve Block - 8 to 12 mL.

For surgery of the upper lips and nostrils, trephining of the maxillary sinuses and extracting upper incisor and cheek teeth.

Mandibular Nerve Block - 10 to 20 mL.

For surgery of the lower lip, mandible and lower molar and incisor teeth.

Median and Ulnar Nerve Block - 15 to 20 mL.

For surgery distal to the carpus and for diagnosis of lameness.

Volar and Plantar Nerve Blocks - 5 to 10 mL.

For surgery of the extremities of the feet and the diagnosis of lameness.

Posterior Digital Nerve Block - 3 to 5 mL.

For diagnosis of navicular disease.

Epidural Block (Standing Animal) - 4 to 10 mL.

For surgery of the tail, anus and rectum, vulva and vagina and perineum.

CATTLE: Infiltration Anesthesia - 5 to 100 mL. Subcutaneously or intramuscularly. For major surgery and suturing wounds.

Regional Nerve Blocks

Cornual Nerve Block - 10 to 15 mL.

For dehorning of bulls.

Epidural Block (Standing Animal) - 4 to 8 mL.

For surgery of the tail, anus, rectum, vulva and vagina and perineum; relaxation of the penis; counteracting excessive straining during replacement of the prolapsed uterus or vagina; removal of urethral calculi in feedlot steers.

Paravertebral Block - 50 to 80 mL.

For Laparotomy.

Calves And Sheep

Epidural Block - 3 to 10 mL.

Sows

Infiltration Anesthesia - 60 to 80 mL.

For Laparotomy.

Dogs

Local infiltration for minor surgery and suturing wounds - 2 to 10 mL.

Tail Amputation - 0.5 to 5 mL.

Cats

Local subcutaneous infiltration for minor surgery - 0.5 to 4 mL.

Contraindications

Epidural anesthesia is contraindicated in dogs which are highly distressed, due to the danger of shock. Use should be restricted to calm animals. Use with extreme care in animals with severe shock, heart block, neurological diseases, spinal deformities, septicemia and severe hypotension or hypertension. Avoid injection at the actual surgery site since it may delay healing.

Epinephrine may compromise circulation if injected into areas with end artery blood flow (e.g. ears, digits, tail) and therefore, this product should not be used in these areas.

Do not administer intravenously. Convulsions and shock may occur in sensitive animals if large doses of the drug are given intravenously (inadvertently) or intrathecally. This may be treated by injecting a short acting barbiturate intravenously to control central nervous system stimulation and immediately administering artificial respiration or oxygen.

Lidocaine HCl 2% Caution

Transient drowsiness may occur in animals receiving large doses of Lidocaine HCl. Signs of toxicity include: loss of consciousness, drop in blood pressure and respiratory collapse. The degree of toxicity depends upon the vascularization of the area. Spasm of certain muscle groups or convulsions may also occur. Treatment for toxicity is as follows: lowered head, artificial respiration, oxygen and I.V. pressor agents. Convulsions and spasm are controlled by means of small amounts of I.V. ultra short-acting barbiturates.

Warning

Treated animals must not be slaughtered for use in food for at least 5 days after the latest treatment with this drug.

This drug is not to be administered to horses that are to be slaughtered for use in food.

Milk taken from treated animals during treatment and within 96 hours after the latest treatment must not be used as food.

Keep out of reach of children.

Note

Lidocaine HCl is acidic and can react chemically with the metallic parts of syringes. Injections should therefore be made immediately after withdrawal from the bottle. Excessive heat will cause oxidation of the epinephrine, concurrently making the solution pink in colour. Should this occur, the bottle should be discarded.

Storage

Store at room temperature between 15°C-30°C. Protect from light. Keep from freezing.

Wyeth Animal Health, Division of Wyeth Canada, 400 Michener Road, Guelph, Ontario N1K 1E4

Net
250 mL	8LID011A	A7694C

Nac No.

11983800