K-Caps

Vitamin K₁ Capsules, 25 Mg

Contents

Each capsule contains 25 mg of Phytonadione.

Description

K-CAPS (Vitamin K₁ Capsules) contain phytonadione with excipients in an artificially colored soft gelatin shell.

Actions

K-CAPS (Vitamin K₁ Capsules) for oral administration possesses the same type and degree of activity as does naturally occurring vitamin K. The primary function of Vitamin K is to stimulate the production via the liver of active prothrombin from a precursor protein. The mechanism by which vitamin K promotes formation of prothrombin at the molecular level has not been established.

K-Caps Indications

K-CAPS (Vitamin K₁ Capsules) are indicated in dogs and cats to counter hypoprothrombinemia induced by ingestion of coumarin-based compounds, common ingredients of commercial rodenticides, and other drug induced hypoprothrombinemia where it is definitely shown that the result is due to interference with vitamin K metabolism, e.g. salicylates.

Note

Regular determinations of prothrombin time response should be performed to guide in the initial and subsequent administration of Vitamin K₁ oral capsules. The dosage should be adjusted accordingly.

Contraindication

Hypersensitivity to any component of this medication.

Warnings

It is recommended that Vitamin K₁ oral capsules be used in follow-up therapy only after administration of Vitamin K₁ injection and hospitalization is no longer required. An immediate coagulant effect should not be expected after administration of phytonadione when administered orally.

Phytonadione will not counteract the anticoagulant action of heparin.

Repeated large doses of Vitamin K₁ are warranted in hepatic disease if the response to the initial therapy is unsatisfactory. Failure to respond to Vitamin K1 may indicate that the condition being treated is inherently unresponsive to Vitamin K₁.

Precautions

Protect from light at all times. Temporary resistance to prothrombin-depressing anticoagulants may result, especially when larger doses of phytonadione are used.

K-Caps Dosage And Administration

Dogs and Cats

Hypoprothrombinemia (with hemorrhage) - Administer orally at the rate of 2.5-5 mg/kg body weight (1 capsule per each 22 pounds of body weight for lower dosage or 1 capsule per each 11 pounds body weight for higher dosage) daily as conditions require up to 3 weeks.

Frequency and amount of oral administration should be guided by regular determination of prothrombin time.

The smallest effective dose should be sought to minimize the risk of adverse reaction.

K-Caps Caution

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

How Supplied

K-CAPS (Vitamin K₁ Capsules) are available in bottles of 50 capsules each.

Keep Out Of Reach Of Children

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