Gentadip

This page contains information on Gentadip for veterinary use.
The information provided typically includes the following:
  • Gentadip Indications
  • Warnings and cautions for Gentadip
  • Direction and dosage information for Gentadip

Gentadip

This treatment applies to the following species:
Manufacturer: Med-Pharmex

(GENTAMICIN SULFATE SOLUTION)

For Turkey Egg Dipping

50 mg/mL

ANADA #200-191, approved by FDA.

Description

Each milliliter of Gentamicin Sulfate Solution for Turkey Egg Dipping contains gentamicin sulfate equivalent to 50 mg gentamicin base, 3.2 mg sodium bisulfite, 0.1 mg edetate disodium, 7.46 mg sodium acetate, 3.0 mg glacial acetic acid; 1.8 mg methylparaben and 0.2 mg propylparaben as preservatives, purified water q.s.

CHEMISTRY: Gentamicin Sulfate is a bactericidal aminoglycoside antibiotic derived from Micromonospora purpurea of the Actinomycetes group. It is a powder, readily soluble in water and basic in nature. Gentamicin aqueous solutions do not require refrigeration and are stable over a wide range of temperatures and pH.

Gentadip Indications

Gentamicin Sulfate for Turkey Egg Dipping is recommended as an aid in the reduction or elimination of the following microorganisms from turkey hatching eggs:

Arizona hinshawii (paracolon)

Salmonella st. paul

Mycoplasma meleagridis.

Directions For Use

Gentamicin Sulfate Solution should be added to clean water to provide a dip solution with a gentamicin concentration of 250 to 1000 ppm. A gentamicin concentration of 500 ppm is recommended.

To make a solution of approximately 500 ppm gentamicin activity, mix one bottle of Gentamicin Sulfate Solution for Turkey Egg Dipping to each 2 gallons of water.

Mixing Chart

Gentamicin ppm

Water Gallons

Grams Gentamicin Needed

Bottles Gentamicin Sol.
to be added

250

4

4

1

40

40

10

80

80

20

500

2

4

1

40

80

20

80

160

40

1000

1

4

1

40

160

40

80

320

80

Egg dipping procedures - These are general suggestions and will vary with equipment and operator.

Temperature differential method - clean eggs should be warmed 3 to 6 hours at approximately 100°F, then immediately dipped in gentamicin solution maintained at about 40°F and held completely submerged for 10 - 15 minutes.

Pressure differential method - clean eggs should be held completely submerged in a gentamicin solution under a vacuum of about 27.5 - 38 cm mercury for 5 minutes, followed by additional soaking in gentamicin solution for approximately 10 minutes at atmospheric pressure.

Egg dipping solutions should be maintained free of dirt and organic contamination. Gentamicin is stable in aqueous solution with the exception of action from microorganisms.

It is recommended that periodically, samples of egg dig solution be sent to a laboratory, such as a State Laboratory, using standard culture techniques to monitor for bacterial, mold or yeast contamination not sensitive to gentamicin.

Since gentamicin sulfate is stable at autoclaving temperatures and pressures, the egg dip solutions may undergo pasteurization procedures to eliminate possible microbial contamination.

Contraindications

There are no known contraindications for Gentamicin Sulfate Solution for Turkey Egg Dipping when used as directed.

Precautions

Filters composed of cellulose, diatomaceous earth or asbestos may remove significant amounts of gentamicin from the dipping solution during filtration.

It is recommended that egg dip solutions be analyzed for antibiotic concentration to establish whether the filtering system is removing a significant amount of antibiotic.

Warning

For use in the dipping treatment of turkey hatching eggs only. Eggs which have been dipped in Gentamicin Sulphate solution should not be used for food.

How Supplied

Gentamicin Sulfate Solution for Turkey Egg Dipping, 50 mg/mL, is available in 2-2/3 fl. oz. (80 mL) screw top bottles.

Store between 15° and 30°C (59°F and 86°F).

April 1997

Med-Pharmex, Inc., Pomona, CA 91767

NAC No.: 10270041

MED-PHARMEX, INC.
2727 THOMPSON CREEK ROAD, POMONA, CA, 91767-1861
Telephone:   909-593-7875
Fax:   909-593-7862
Website:   www.med-pharmex.com
Email:   egbert@medpharmex.com
Every effort has been made to ensure the accuracy of the Gentadip information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2014 North American Compendiums. Updated: 2014-09-05

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