Exodus Paste

This page contains information on Exodus Paste for veterinary use.
The information provided typically includes the following:
  • Exodus Paste Indications
  • Warnings and cautions for Exodus Paste
  • Direction and dosage information for Exodus Paste

Exodus Paste

This treatment applies to the following species:
Manufacturer: Bimeda

(pyrantel pamoate)

Equine Anthelmintic

Apple Flavored!

ANADA 200-350, Approved By FDA

For Oral Use in Horses Only

Exodus® Paste (pyrantel pamoate) is a pale yellow to buff paste containing 43.9% w/w pyrantel pamoate in an inert vehicle. Each 23.6 g single-dose syringe contains 3.6 grams pyrantel base in 23.6 grams paste. Each 47.2 g multi-dose syringe contains 7.2 grams pyrantel base in 47.2 grams paste. Each milliliter contains 171 milligrams pyrantel base as pyrantel pamoate.

READ ENTIRE CARTON CAREFULLY BEFORE USING THIS PRODUCT

Composition

Pyrantel pamoate is a compound belonging to a family classified chemically as tetrahydropyrimidines. It is a yellow, water-insoluble crystalline salt of the tetrahydropyrimidine base and pamoic acid containing 34.7% base activity. The chemical structure and name are given below:

Chemical Name:

(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)-vinyl]-pyrimidine 4,4’ methylenebis [3-hydroxy-2-naphtholate] (1:1)

Exodus Paste Indications

For the removal and control of mature infections of large strongyles (Strongylus vulgaris, S. edentatus, S. equinus); small strongyles; pinworms (Oxyuris equi); and large roundworms (Parascaris equorum) in horses and ponies.

Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

Dosage And Treatment

Exodus® Paste (pyrantel pamoate) is to be administered as a single oral dose of 3 milligrams pyrantel base per pound of body weight. The 23.6 g syringe has four weight mark increments. The 47.2 g syringe has eight weight mark increments. Each weight mark indicates the recommended dose for 300 pounds of body weight. One-half 47.2 g syringe treats a 1200 lb horse.

DOSAGE for Single-Dose 23.6 g Syringe:

Body Weight Range

Quantity

mg Pyrantel Base

up to 300 lb

1/4 syringe

900 mg

301 to 600 lb

1/2 syringe

1800 mg

601 to 900 lb

3/4 syringe

2700 mg

901 to 1200 lb

1 full syringe

3600 mg

DOSAGE for Multi-Dose 47.2 g Syringe:

Body Weight Range

Quantity

mg Pyrantel Base

up to 300 lb

1/8 syringe

900 mg

301 to 600 lb

1/4 syringe

1800 mg

601 to 900 lb

3/8 syringe

2700 mg

901 to 1200 lb

1/2 syringe

3600 mg

NOTE: Position ring-gauge over appropriate mark on plunger.

For maximum control of parasitism, it is recommended that foals (2-8 months of age) be dosed every 4 weeks. To minimize the potential source of infection that the mare may pose to the foal, the mare should be treated 1 month prior to anticipated foaling date followed by re-treatment 10 days to 2 weeks after birth of foal. Horses and ponies over 8 months of age should be routinely dosed every 6 weeks.

It is recommended that severely debilitated animals not be treated with this preparation.

Administration

After removing the cap, the paste should be deposited on the dorsum of the tongue. Introduce the nozzle end of the syringe at the corner of the mouth. Direct the syringe backwards and depress the plunger to deposit the paste onto the tongue. Given in this manner, it is unlikely that rejection of the paste will occur. Raising the horse’s head sometimes assists in the swallowing process. When only part of the paste has been used, replace the cap on the syringe nozzle.

Efficacy

Critical (worm count) studies in horses demonstrated that pyrantel pamoate administered at the recommended dosage was efficacious against mature infections of Strongylus vulgaris (>90%), S. edentatus (69%), S. equinus (>90%), Oxyuris equi (81%), Parascaris equorum (>90%), and small strongyles (>90%).

WARNING: Do not use in horses intended for human consumption.

KEEP THIS AND ALL MEDICATIONS OUT OF REACH OF CHILDREN

FOR ORAL USE ONLY

FOR ANIMAL USE ONLY

RECOMMENDED STORAGE: Store at controlled room temperature 15°-30°C (59°-86°F).

Exodus is a Registered Trademark of Bimeda, Inc.

Manufactured by: Bimeda-MTC Animal Health Inc., Cambridge, Ontario, Canada N3C 2W4

Bimeda, Inc. and Bimeda-MTC Animal Health Inc. are Divisions of Cross Vetpharm Group Ltd.

Manufactured for: Bimeda, Inc., Le Sueur, MN 56058

www.bimeda.com

Net Contents:

Product No.

 

23.6 g Single-Dose

1EXO001

8PYR003E Rev. 05/11

47.2 g Multi-Dose

1EXO002

8PYR006B Rev. 04/11

8PYR005D Rev. 04/11

NAC No.: 13990638

BIMEDA, INC.
Div. Cross Vetpharm Group, Ltd.

ONE TOWER LANE-SUITE 2250, OAKBROOK TERRACE, IL, 60181
Telephone:   630-928-0361
Fax:   630-928-0362
Website:   www.bimedaus.com
Email:   sales@bimedaus.com
Every effort has been made to ensure the accuracy of the Exodus Paste information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2014 North American Compendiums. Updated: 2014-04-11

(web5)