Duplocillin LA (Canada)

FOR VETERINARY USE ONLY

D.I.N. 01983377

ACTIVE INGREDIENTS: DESCRIPTION

Duplocillin^® LA is a sterile aqueous suspension for injection, containing per mL 150,000 I.U. procaine penicillin G (B.P.) and 150,000 I.U. benzathine penicillin G (B.P.) and as preservatives, 1.2 mg methylparahydroxybenzoate and 0.13 mg propylparahydroxybenzoate.

INDICATIONS

Duplocillin^® LA is indicated as an aid in the treatment of local and systemic infections caused by bacteria including metritis, strangles and tetanus in horses, blackleg, foot rot, metritis and shipping fever complex in cattle, erysipelas, mastitis and metritis in swine, clostridial diseases and foot rot in sheep and metritis respiratory infections and wound infections in dogs and cats, where a prolongation of the therapeutic period from a single injection is required. Penicillin has been shown in vitro to be effective against gram positive aerobic bacteria, including certain strains of Staphylococcus aureus, Streptococcus Spp., Actinomyces Spp., (Corynebacteria) and Erysipelothrix rhusiopathiae. Sensitive gram positive anaerobic bacteria include certain strains of Clostridia Spp. Penicillin has also been shown in vitro to be effective against certain gram negative bacteria, including certain strains of Pasteurella multocida and Actinobacillus (Haemophilus) pleuropneumoniae.

DOSAGE AND ADMINISTRATION:

Duplocillin^® LA should be given by deep intramuscular injection. Shake well before use.

The following dosage rates are recommended.

Horses and Cattle: 6,000 I.U. each of procaine penicillin G and benzathine penicillin G/kg of body weight. 1 mL/25 kg, 10 mL/250 kg, 16 mL/400 kg, or 20 mL/500 kg of body weight.

Sheep and swine: 7,500 I.U. each of procaine penicillin G and benzathine penicillin G/kg of body weight. 1 mL/20 kg, 2 mL/40 kg, or 3 mL/60 kg of body weight.

Dogs and cats: 15,000 I.U. each of procaine penicillin G and benzathine penicillin G/kg of body weight. 0.5 mL/5 kg, 1 mL/10 kg, or 2 mL/20 kg of body weight.

Accurate determination of body weight is important to ensure proper dosage. Repeat the dose in 3 to 5 days if required. The usual aseptic precautions should be followed.

PRECAUTION(S): STORAGE

Store below 15°C. Do not freeze.

CAUTION(S)

Duplocillin^® LA should not be administered to animals known to be allergic to penicillin. In case of anaphylactic reactions, administer epinephrine immediately. If no improvement of the condition is noted within 36-48 hours, the treatment/diagnosis should be reevaluated and a veterinarian consulted. In suckling and fattening pigs, administration of procaine penicillin G will occasionally cause a transient pyrexia, vomiting, shivering and incoordination. Abortions have also been reported in pregnant sows and gilts.

For intramuscular use only.

WARNINGS

Not for use in lactating dairy cows. Treated animals must not be slaughtered for food purposes for at least 14 days after the last treatment with this product. This drug is not to be administered to horses that are to be slaughtered for use in food.

INTERVET INTERNATIONAL B.V BOXMER - HOLLAND

Distributed by: INTERVET CANADA CORP., 16750, route Transcanadienne, Kirkland QC, H9H 4M7

For technical enquiries, call toll free 1 888 306-0069.

092063C 0042.570.4330

092063C 1.02

Nac No.