Distox (Canada)

Mink Distemper-enteritis Vaccine

Modified Live and Killed Virus

Clostridium Botulinum Type C Bacterin-toxoid

DIRECTIONS FOR USE , READ CAREFULLY

This vaccine is made up of two components: a lyophilized (freeze-dried) vaccine containing a modified live distemper virus grown in tissue culture and combined with stabilizing agents; and a liquid fraction containing an inactivated mink enteritis virus grown in a feline cell line combined with Clostridium botulinum Type C bacterin-toxoid with an aluminum adjuvant. The liquid bacterin-toxoid component serves as diluent for rehydrating the dried distemper vaccine and has been processed and tested especially to allow mixing of this triple combination vaccine in the field.

This vaccine is for use in mink 10 weeks of age or older, as an aid in preventing distemper, virus enteritis and type C botulism through vaccination by subcutaneous injection.

WHEN TO VACCINATE

Mink should be vaccinated at 6 weeks of age for mink virus enteritis and then at 10 weeks or older with DISTOX. Revaccinate breeders one month before mating season for distemper and type C botulism.

PREPARATION OF THE VACCINE

1. Do not open and mix the vaccine until ready for use.

2. Mix only one vial at a time and use entire contents within two hours.

3. Disinfect exposed rubber stoppers with alcohol or other disinfectants.

4. Shake the liquid bacterin-toxoid component well before use.

5. Using a sterile transfer needle, or a sterile needle and syringe, transfer the entire contents of the liquid bacterin-toxoid bottle into the bottle of dried distemper vaccine. (Insert transfer needle into bacterin-toxoid diluent first, turn bacterin-toxoid diluent bottle upside down, then insert other end of transfer needle into dried distemper vaccine bottle. Bacterin-toxoid diluent will be drawn into distemper vaccine bottle by vacuum.)

6. As soon as all bacterin-toxoid diluent has been transferred, shake the completed vaccine well to suspend evenly.

7. The vaccine is now ready for use.

CONTRAINDICATIONS

Mink kits younger than 10 weeks of age and born from distemper-vaccinated female breeders may possess strong maternal immunity which can interfere with the distemper fraction of this vaccine. Thus, vaccination of such mink is not recommended before 10 weeks of age.

HOW TO VACCINATE

For all mink, inject 1.0 mL (cc) subcutaneously under the skin, preferably in the region of the armpit (axillary space).

CAUTION

1. For veterinary use only.

2. Vaccinate only healthy animals. Although disease may not be evident, Aleutian disease, urinary tract infections, boils or other disease conditions may cause complications or reduce protection.

3. Use only sterile needles and syringes to inject the vaccine. Syringes and needles may be sterilized by boiling for 15 to 20 minutes. DO NOT disinfect with chemicals since they may destroy the distemper vaccine virus.

4. Do not transfer vaccine to other containers.

5. Protect the vaccine from excessive light and heat.

6. Use entire contents when first opened. Do not save any unused portion of the vaccine mixture for later use.

7. Do not spill or spatter the vaccine. Burn empty bottles, caps and all unused vaccine and accessories.

8. Do not dilute the vaccine or otherwise stretch the dosage.

9. Store at 2° to 7° C (35° to 45° F). Do not freeze.

10. This vaccine has been demonstrated to be safe and efficacious when used according to directions. As with any vaccine, it may not be effective when used in animals with significant levels of maternal immunity.

11. If anaphylactic reaction occurs, administer epinephrine.

RECORDS

Keep a record of vaccine type, quantity, serial number, expiration date, and place of purchase; the date and time of vaccination; the number, age, and location of the mink; names of operators performing the vaccination and any observed reactions.

This vaccine contains gentamicin and amphotericin B as preservatives.

U.S. Veterinary License No. 165A

Schering-Plough Animal Health Corp., Omaha, Nebraska, 68103, USA

1 800 219-9286 (USA)

1 888 306-0069 (Canada)

Copyright ©1989, 1990, 1992, 1998, 2001 Schering-Plough Animal Health Corp., All rights reserved.

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