YASMIN 0.03 MG/ 3 MG FILM-COATED TABLETS

Active substance: ETHINYLESTRADIOL

View full screen / Print PDF » Download PDF ⇩
Transcript
Page:

1 of

13

Yasmin PIL
Package booklet: Information for the user
Yasmin 0.03 mg / 3 mg film-coated tablets
Ethinylestradiol / Drospirenone

Read all of this booklet carefully before you start taking this medicine because it contains
important information for you.
- Keep this booklet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others. It may harm
them.
- If you get any side effects, talk to your doctor or pharmacist. This includes any possible side
effects not listed in this booklet. See section 4.
What is in this booklet

1.  What is Yasmin and what it is used for ..................................................................................... 2 
2.  What you need to know before you take Yasmin...................................................................... 2 
When you should not use Yasmin ............................................................................................. 2 
Warnings and precautions ......................................................................................................... 3 
Yasmin and venous and arterial blood clots .............................................................................. 3 
Yasmin and cancer .................................................................................................................... 5 
Bleeding between periods.......................................................................................................... 5 
What to do if no bleeding occurs during the seven pill-free days ............................................. 5 
Other medicines and Yasmin..................................................................................................... 5 
Yasmin with food and drink ...................................................................................................... 6 
Laboratory tests ......................................................................................................................... 6 
Pregnancy .................................................................................................................................. 6 
Breast-feeding............................................................................................................................ 6 
Driving and using machines ...................................................................................................... 6 
Yasmin contains lactose ............................................................................................................ 6 
3.  How to Take Yasmin ................................................................................................................. 6 
When can you start with the first strip? ..................................................................................... 7 
If you take more Yasmin than you should................................................................................. 8 
If you forget to take Yasmin ...................................................................................................... 8 
What to do in the case of vomiting or severe diarrhoea .......................................................... 10 
Delaying your period: what you need to know ....................................................................... 10 
Changing the first day of your period: what you need to know .............................................. 10 
If you stop taking Yasmin ....................................................................................................... 10 

V024_0

Page 1 of 13

Page:

2 of

13

Yasmin PIL
4.  Possible side effects ................................................................................................................. 10 
5.  How to Store Yasmin .............................................................................................................. 12 
6.  Contents of the pack and other information ............................................................................ 13 
1.

What is Yasmin and what it is used for



Yasmin is a contraceptive pill and is used to prevent pregnancy.



Each light yellow tablet contains a small amount of two different female hormones, namely
drospirenone and ethinylestradiol.



Contraceptive pills that contain two hormones are called “combination” pills.

2.

What you need to know before you take Yasmin

General notes
Before you can begin taking Yasmin, your doctor will ask you some questions about your personal health
history and that of your close relatives. The doctor will also measure your blood pressure and, depending
upon your personal situation, may also carry out some other tests.
In this booklet, several situations are described where you should stop using Yasmin, or where the
reliability of Yasmin may be decreased. In such situations you should either not have sex or you should
take extra non-hormonal contraceptive precautions, e.g. use a condom or another barrier method. Do not
use rhythm or temperature methods. These methods can be unreliable because Yasmin alters the monthly
changes of body temperature and cervical mucus.
Yasmin, like other hormonal contraceptives, does not protect against HIV infection (AIDS) or any
other sexually transmitted disease.
When you should not use Yasmin

Do not take Yasmin





if you have (or have ever had) a blood clot in a blood vessel of the leg (thrombosis), of the lung
(pulmonary embolism) or other organs
if you have (or have ever had) a heart attack or stroke
if you have (or have ever had) a disease that can be an indicator of a heart attack in the future (for
example, angina pectoris, which causes severe pain in the chest) or of a stroke (for example, a passing
slight stroke with no residual effects)
if you have a disease that may increase the risk of a blood clot in the arteries. This applies to the
following diseases:
o diabetes with damaged blood vessels
o very high blood pressure
o a very high level of fat in the blood (cholesterol or triglycerides)

V024_0

Page 2 of 13

Page:

3 of

13

Yasmin PIL









if you have a disturbance of blood clotting (for example, protein C deficiency)
if you have (or have ever had) a certain form of migraine (with so-called focal neurological
symptoms)
if you have (or have ever had) liver disease and your liver function is still not normal
if your kidneys are not working well (renal failure)
if you have (or have ever had) had a tumour in the liver
if you have (or have ever had) or if you are suspected of having breast cancer or cancer of the genital
organs
if you have any unexplained bleeding from the vagina
if you are allergic to ethinylestradiol or drospirenone, or any of the other ingredients of this medicine
(listed in section 6). This may cause itching, rash or swelling.

Warnings and precautions
In some situations you need to take special care while using Yasmin or any other combination pill, and
your doctor may need to examine you regularly. If any of the following conditions applies to you, tell
your doctor before starting to use Yasmin. Also, if any of the following applies or if any of the conditions
develops or worsens while you are taking Yasmin consult your doctor:
If you have:














a close relative who has ever had breast cancer
a disease of the liver or the gallbladder
diabetes
depression
Crohn’s disease or inflammatory bowel disease (ulcerative colitis)
a blood disease called HUS (haemolytic uraemic syndrome) that causes kidney damage
a blood disease called sickle cell anaemia
epilepsy (see page 6 “ Other medicines and Yasmin”)
a disease of the immune system called called SLE (systemic lupus erythematosus)
a disease that first appeared during pregnancy or earlier use of sex hormones (for example, hearing
loss, a blood disease called porphyria, yellowing of the skin or eyes (jaundice), itching of the whole
body (pruritis), skin rash with blisters during pregnancy (gestational herpes), a nerve disease causing
sudden movements of the body (Sydenham’s chorea)
ever had a discolouration of the skin especially on the face or neck known as “pregnancy patches”
(chloasma). If so, avoid direct sunlight or ultraviolet light.
hereditary angioedema, products containing oestrogens may cause or worsen the symptoms. You
should see your doctor immediately if you experience symptoms of angioedema such as swollen face,
tongue and/or throat and/or difficulty swallowing or hives together with difficulty breathing.

Yasmin and venous and arterial blood clots
The use of any combination pill, including Yasmin, increases a woman’s risk of developing a venous
blood clot (venous thrombosis) compared with women who do not take any contraceptive pill.
The risk of a venous blood clot in users of combination pills increases:


with increasing age

V024_0

Page 3 of 13

Page:

4 of

13

Yasmin PIL




if you are overweight
if one of your close relatives has ever had a blood clot in the leg, lung (pulmonary embolism), or
other organ at a young age
if you need to have surgery, if you have had a serious accident or if you are immobilised for a long
time. It is important to tell your doctor that you are taking Yasmin as you may have to stop taking it.
Your doctor will tell you when to start again. This is usually about two weeks after you are back on
your feet.

Your chances of having a blood clot are increased by taking the Pill.
- Of 100,000 women who are not on the Pill and not pregnant, about 5-10 may have a blood clot in a year.
- Of 100,000 women taking a Pill like Yasmin, 30-40 may have a blood clot in a year, the exact number is
unknown.
- Of 100,000 women who are pregnant, around 60 may have a blood clot in a year.
A blood clot in the veins may travel to the lungs and may block blood vessels (called a lung embolus).
Formation of blood clots in the veins may be fatal in 1-2% of cases.
The level of risk may vary according to the type of pill you take. Discuss with your doctor the available
options
The use of combination pills has been connected with an increase of the risk of an arterial blood clot
(arterial thrombosis), for example, in the blood vessels of the heart (heart attack) or the brain (stroke).
The risk of an arterial blood clot in users of combination pills increases if you:








smoke. You are strongly advised to stop smoking when you use Yasmin, especially if you are
older than 35 years.
have an increased fat content of your blood (cholesterol or triglycerides)
are overweight
have a close relative who ever had a heart attack or stroke at a young age
have high blood pressure
suffer from migraine
have a problem with your heart (valve disorder, a disturbance of the cardiac rhythm)

Talk to your doctor before taking Yasmin
Stop taking Yasmin and contact your doctor immediately if you notice possible signs of a blood clot,
such as:











severe pain and/or swelling in one of your legs
sudden severe pain in the chest which may reach the left arm
sudden breathlessness
sudden cough without an obvious cause
any unusual, severe or long-lasting headache or worsening of migraine
partial or complete blindness or double vision
difficulty in speaking or inability to speak
giddiness or fainting
weakness, strange feeling, or numbness in any part of the body
severe pain in the abdomen (known as acute abdomen)

V024_0

Page 4 of 13

Page:

5 of

13

Yasmin PIL

Yasmin and cancer
Breast cancer has been observed slightly more often in women using combination pills, but it is not
known whether this is caused by the treatment. For example it may be that more tumours are detected in
women on combination pills because they are examined by their doctor more often. The risk of breast
tumours becomes gradually less after stopping the combination hormonal contraceptives. It is important
to regularly check your breasts and you should contact your doctor if you feel any lump.
In rare cases, benign liver tumours, and in even fewer cases malignant liver tumours have been reported
in pill users. Contact your doctor if you have unusually severe abdominal pain.
Bleeding between periods
During the first few months that you are taking Yasmin, you may have unexpected bleeding (bleeding
outside the seven pill-free days). If this bleeding occurs for more than a few months, or if it begins after
some months, contact your doctor as they must find out if anything is wrong.
What to do if no bleeding occurs during the seven pill-free days
If you have taken all the tablets correctly, have not had vomiting or severe diarrhoea and you have not
taken any other medicines, it is highly unlikely that you are pregnant.
If the expected bleeding does not happen twice in succession, you may be pregnant. Contact your doctor
immediately. Only start the next strip if you are sure that you are not pregnant.
Other medicines and Yasmin
Always tell your doctor which medicines or herbal products you are already using. Also tell any other
doctor or dentist who prescribes another medicine (or the pharmacist) that you are taking Yasmin. They
can tell you if you need to take additional contraceptive precautions (for example condoms) and if so, for
how long.
Some medicines can have an influence on the blood levels of Yasmin and can make it less effective in
preventing pregnancy, or can cause unexpected bleeding. These include:


medicines used for the treatment of



tuberculosis (e.g. rifampicin)



HIV and Hepatitis C Virus infections (so called protease inhibitors and non-nucleoside
reverse transcriptase inhibitors such as ritonavir, nevirapine) or other infections (griseofulvin)





epilepsy (e.g. primidone, phenytoin, barbiturates, carbamazepine, oxcarbazepine)

high blood pressure in the blood vessels in the lungs (bosentan)

the herbal remedy St. John’s wort

Yasmin may influence the effect of other medicines, e.g.


medicines containing ciclosporin



the anti-epileptic lamotrigine (this could lead to an increased frequency of seizures)

Ask your doctor or pharmacist for advice before taking any medicine.

V024_0

Page 5 of 13

Page:

6 of

13

Yasmin PIL
Yasmin with food and drink
Yasmin may be taken with or without food, if necessary with a small amount of water.

Laboratory tests
If you need a blood test, tell your doctor or the laboratory staff that you are taking the pill, because
hormonal contraceptives can affect the results of some tests.
Pregnancy
If you are pregnant, you must not take Yasmin. If you become pregnant while taking Yasmin you must
stop taking it immediately and contact your doctor. If you want to become pregnant, you can stop taking
Yasmin at any time (see also page 11 “If you stop taking Yasmin”).
Ask your doctor or pharmacist for advice before taking any medicine.
Breast-feeding
Use of Yasmin is generally not advisable when a woman is breast-feeding. If you want to take the pill
while you are breast-feeding you should contact your doctor.
Ask your doctor or pharmacist for advice before taking any medicine.
Driving and using machines
There is no information suggesting that use of Yasmin affects driving or the use of machines.
Yasmin contains lactose
If you cannot tolerate certain sugars, contact your doctor before you take Yasmin.
3.

How to Take Yasmin

Take Yasmin every day for 21 days
Yasmin comes in strips of 21 pills, each marked with a day of the week.
• Take your pill at the same time every day.
• Start by taking a pill marked with the correct day of the week.
• Follow the direction of the arrows on the strip. Take one pill each day, until you have finished all 21
pills.
• Swallow each pill whole, with water if necessary. Do not chew the pill.
Then have seven pill-free days
After you have taken all 21 pills in the strip, you have seven days when you take no pills. So, if you take
the last pill of one pack on a Friday, you will take the first pill of your next pack on the Saturday of the
following week.

V024_0

Page 6 of 13

Page:

7 of

13

Yasmin PIL
Within a few days of taking the last pill from the strip, you should have a withdrawal bleed like a period.
This bleed may not have finished when it is time to start your next strip of pills.
You don’t need to use extra contraception during these seven pill-free days – as long as you have taken
your pills correctly and start the next strip of pills on time.
Then start your next strip
Start taking your next strip of Yasmin after the seven pill-free days – even if you are still bleeding.
Always start the new strip on time.
During the seven pill-free days, when you take no tablets, bleeding should begin (so-called withdrawal
bleeding). This usually starts on the 2nd or 3rd day after the last tablet of Yasmin. Start the following strip
after the last day of the seven pill-free days, whether your bleeding has stopped or not.
When can you start with the first strip?


If you have not used a contraceptive with hormones in the previous month
Begin with Yasmin on the first day of your cycle (that is, the first day of your period). If you start
Yasmin on the first day of your period you are immediately protected against pregnancy. You may
also begin on day 2-5 of the cycle, but then you must use extra protective measures (for example, a
condom) for the first 7 days.



Changing from a combination hormonal contraceptive, or combination contraceptive vaginal ring or
patch
You can start Yasmin preferably on the day after the last active tablet (the last tablet containing the
active substances) of your previous pill, but at the latest on the day after the tablet-free days of your
previous pill finish (or after the last inactive tablet of your previous pill). When changing from a
combination contraceptive vaginal ring or patch, follow the advice of your doctor.



Changing from a progestogen-only-method (progestogen-only pill, injection, implant or a
progestogen-releasing intrauterine system IUS)
You may switch any day from the progestogen-only pill (from an implant or an IUS on the day of its
removal, from an injectable when the next injection would be due) but in all of these cases use extra
protective measures (for example, a condom) for the first 7 days of taking Yasmin.



After a miscarriage or abortion
If you have had a miscarriage or abortion during the first three months of pregnancy, your doctor
may tell you to start taking Yasmin straight away. This means that you will have contraceptive
protection with your first pill.



After having a baby
You can start taking Yasmin between 21 and 28 days after having a baby. If you start later than day
28, use a so-called barrier method (for example, a condom) during the first seven days of taking
Yasmin.
If, after having a baby, you have had sex before starting Yasmin (again), you must first be sure that
you are not pregnant or wait until your next period.

V024_0

Page 7 of 13

Page:

8 of

13

Yasmin PIL



If you are breast-feeding and want to start Yasmin after having a baby
Read the section on “Breast-feeding”, page 6.

Ask your doctor what to do if you are not sure when to start.
If you take more Yasmin than you should
There are no reports of serious harmful results of taking too many Yasmin tablets.
If you take several tablets at once then you may have symptoms of nausea or vomiting. Young girls may
have bleeding from the vagina.
If you have taken too many Yasmin tablets, or you discover that a child has taken some, ask your doctor
or pharmacist for advice.

If you forget to take Yasmin


If you are less than 12 hours late taking a tablet, the protection against pregnancy is not reduced.
Take the tablet as soon as you remember and then take the following tablets again at the usual time.



If you are more than 12 hours late taking a tablet, the protection against pregnancy may be reduced.
The greater the number of tablets you have forgotten, the greater is the risk of becoming pregnant.

The risk of incomplete protection against pregnancy is greatest if you forget a tablet at the beginning or at
the end of the strip. Therefore, you should keep to the following rules (see also the diagram on page 9):


More than one tablet forgotten in this strip
Contact your doctor.



One tablet forgotten between days 1 - 7

Take the forgotten tablet as soon as you remember, even if that means that you have to take two tablets at
the same time. Continue taking the tablets at the usual time and use extra precautions for the next 7
days, for example, a condom. If you have had sex in the week before forgetting the tablet you may be
pregnant. In that case, contact your doctor.


One tablet forgotten between days 8 – 14

Take the forgotten tablet as soon as you remember, even if that means that you have to take two tablets at
the same time. Continue taking the tablets at the usual time. The protection against pregnancy is not
reduced, and you do not need to take extra precautions. If you forget more than one tablet use an
additional barrier method such as a condom for 7 days.


One tablet forgotten between days 15 - 21



You can choose between two possibilities:

V024_0

Page 8 of 13

Page:

9 of

13

Yasmin PIL
1. Take the forgotten tablet as soon as you remember, even if that means that you have to take two
tablets at the same time. Continue taking the tablets at the usual time. Instead of having seven
pill-free days start the next strip as soon as you have taken the last tablet.
Most likely, you will have a period at the end of the second strip – but you may also have light or
menstruation-like bleeding during the second strip.
2. You can also stop the tablets and go directly to the tablet-free period (record the day on which
you forgot your tablet). If you want to start a new strip on the day you always start, make the
tablet-free period less than 7 days.
If you follow one of these two recommendations, you will remain protected against pregnancy.


If you have forgotten any of the tablets in a strip, and you do not have a bleeding during the first
tablet-free period, you may be pregnant. Contact your doctor before you start the next strip.
Ask your doctor for advice

More than 1 tablet
forgotten in 1 strip

yes
Days 1 - 7

Had sex in the previous week before forgetting?
no
• Take the forgotten tablet
• Use a barrier method (condom) for the
following 7 days and
• Finish strip

Only 1 tablet
forgotten (taken more

Days 8 - 14

• Take the forgotten tablet
• Finish the strip

than 12 hours late)
• Take the forgotten tablet and
• Finish the strip
• Instead of the 7 tablet -free days
• Start the next strip
Days 15 - 21

or
Stop the strip immediately
Begin the gap week (not longer than 7 days)
Then start the next strip

V024_0

Page 9 of 13

Page:

10 of

13

Yasmin PIL

What to do in the case of vomiting or severe diarrhoea
If you vomit within 3-4 hours of taking a tablet or you have severe diarrhoea, there is a risk that the active
substances in the pill will not be fully taken up by your body. The situation is almost the same as
forgetting a tablet. After vomiting or diarrhoea, take another tablet from a reserve strip as soon as
possible. If possible take it within 12 hours of when you normally take your pill. If that is not possible or
12 hours have passed, you should follow the advice given under “If you forget to take Yasmin” on page 8.
Delaying your period: what you need to know
Although it is not recommended, you can delay your period by skipping the seven pill-free days and
going straight to a new strip of Yasmin and finishing it. You may experience light or menstruation-like
bleeding while using this second strip. After the usual pill-free period of 7 days start your next strip.
It is advisable to consult your doctor for advice before deciding to delay your menstrual period.
Changing the first day of your period: what you need to know
If you take the tablets according to the instructions, then your period will begin during the seven pill-free
days. If you have to change this day, make the pill-free period shorter – (but never longer – 7 days is the
maximum!). For example, if you start the seven pill-free days on a Friday, and you want to change this to
a Tuesday (3 days earlier) start a new strip 3 days earlier than usual. If you make the pill-free period very
short (for example 3 days or less) you may not have any bleeding during this time. You may then
experience light or menstruation-like bleeding.
If you are not sure what to do, consult your doctor.
If you stop taking Yasmin
You can stop taking Yasmin whenever you want. If you do not want to become pregnant, ask your doctor
for advice about other reliable methods of birth control. If you want to become pregnant, stop taking
Yasmin and wait for a menstrual period before trying to become pregnant. You will be able to calculate
the expected delivery date more easily.
If you have any further questions on the use of this medicine, ask a doctor or pharmacist.
4.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following is a list of the side effects that have been linked with the use of Yasmin:
Serious side effects: – see you doctor straight away

V024_0

Page 10 of 13

Page:

11 of

Yasmin PIL
Signs of a blood clot:
- a migraine for the first time, a migraine that is worse than normal, or unusually frequent or severe
headaches
- any sudden changes to your eyesight (such as loss of vision or blurred vision)
- any sudden changes to your hearing, speech, sense of smell, taste or touch
- pain or swelling in your leg
- stabbing pain when you breathe
- coughing for no apparent reason
- pain and tightness in the chest
- sudden weakness or numbness in one side or part of your body
- dizziness or fainting

Signs of a severe allergic reaction to Yasmin:
-

swelling of the face, lips, mouth, tongue or throat

Signs of breast cancer include:
-

dimpling of the skin
changes in the nipple
any lumps you can see or feel.

Signs of cancer of the cervix include:
-

vaginal discharge that smells and/or contains blood
unusual vaginal bleeding
pelvic pain
painful sex

Signs of severe liver problems include:
-

severe pain in your upper abdomen
yellow skin or eyes (jaundice)
inflammation of the liver (hepatitis)
your whole body starts itching


If you think you may have any of these, see a doctor straight away. You may need to stop
taking Yasmin

V024_0

Page 11 of 13

13

Page:

12 of

Yasmin PIL
Common side effects (between 1 and 10 in every 100 users may be affected):
- depressive mood
- headache, migraine
- nausea
- breast pain, breast tenderness, menstrual disorders, bleeding between periods, thick whitish vaginal
discharge, vaginal yeast infection
Uncommon side effects (between 1 and 10 in every 1,000 users may be affected):
- breast enlargement
- altered interest in sex
- high blood pressure, low blood pressure
- vomiting, diarrhoea
- acne, severe itching, skin rash, hair loss (alopecia)
- vaginal infection
- fluid retention
- body weight changes
Rare side effects (between 1 and 10 in every 10,000 users may be affected):
- hearing impairment
- asthma
- breast secretion
- blockage of a blood vessel by clot formed elsewhere in the body
- allergic reactions (hypersensitivity)
- the skin conditions erythema nodosum (characterized by painful reddish skin nodules) or erythema
multiforme (characterized by rash with target-shaped reddening or sores).
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not
listed in this booklet. You can also report side effects directly (see details below). By reporting side
effects, you can help provide more information on the safety of this medicine.
United Kingdom
Yellow Card Scheme
Website: www.mhra.gov.uk/yellowcard
Malta
ADR Reporting
The Medicines Authority
Post-Licensing Directorate
203 Level 3, Rue D'Argens
GŻR-1368 Gżira
Website: www.medicinesauthority.gov.mt
e-mail: postlicensing.medicinesauthority@gov.mt

5.

How to Store Yasmin

Keep Yasmin out of the sight and reach of children.

V024_0

Page 12 of 13

13

Page:

13 of

13

Yasmin PIL
Do not store above 25 °C. Store in the original package.
Do not use this medicine after the expiry date which is stated on the packaging after “Do not use after:” or
“EXP.:” The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw
away medicines you no longer use. These measures will help to protect the environment.
6.

Contents of the pack and other information

What Yasmin contains


The active substances are drospirenone and ethinylestradiol.
Each active tablet contains 0.030 milligrams ethinylestradiol and 3 milligrams drospirenone.



Other ingredients in the active tablets are lactose monohydrate, maize starch, pregelatinised maize
starch, povidone K25, magnesium stearate (E470b), hypromellose (E464), macrogol 6000, talc
(E553b), titanium dioxide (E171) and iron oxide yellow (E172).

What Yasmin looks like and content of the pack



Yasmin tablets are film-coated tablets; the core of the tablet is coated. The tablets are light yellow,
round with convex surfaces; one side is embossed with the letters "DO" in a regular hexagon.
Yasmin is available in packs of 1, 3, and 6 blisters each with 21 tablets.

Not all pack sizes may be marketed.
Marketing Authorisation Holder
Bayer plc, Bayer House, Strawberry Hill, Newbury, Berkshire, RG14 1JA
Manufacturer
Bayer Pharma AG
13342 Berlin, Germany

This medicinal product is authorised in the Member States of the EEA under the following
names:


Austria, Belgium, Denmark, Finland, Germany, Greece, Iceland, Ireland, Italy,
Luxembourg, Netherlands, Norway, Portugal, Spain, Sweden, United Kingdom: Yasmin



France: Jasmine

This booklet was last revised in November 2013

V024_0

Page 13 of 13

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Hide
(web3)