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Diltiazem Hydrochloride









Read all of this leaflet carefully before you start taking this medicine.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their
symptoms are the same as yours.
- If any of the side-effects get serious, or if you notice any side-effects not listed in this leaflet,
please tell your doctor or pharmacist.
In this leaflet:
1. What Viazem® XL is and what it is used for
2. Before you take Viazem® XL
3. How to take Viazem® XL
4. Possible side-effects
5. How to store Viazem® XL
6. Further information


The active ingredient in this medicine is called diltiazem. It belongs to a group of medicines called calcium
antagonists which are used to treat high blood pressure, or to help control angina.


Do not take Viazem® XL:
• if you are allergic to diltiazem or any of the other ingredients in Viazem® XL (see list under ‘What Viazem® XL contains).
Azorubine can cause allergic reactions including asthma. Allergy is more common in those people allergic to aspirin
• if you have serious heart problems, particularly if a doctor has told you that you have any of the following conditions;
- Severe bradycardia (a very slow pulse)
- Heart block or pre-excitation syndrome or sick sinus syndrome (conditions in which there are problems with the
control of your heart rate)
- Left ventricular failure
• if you are already taking a medicine containing invabradine for the treatment of certain heart diseases
• if you have unstable angina
• if the patient is a child
• if you are pregnant or are breast-feeding.
If you are not sure, talk to your doctor or pharmacist before taking this medicine.
Take special care with Viazem® XL:
• if you have suffered from any other heart problems
• if you have suffered a stroke
• if you have had liver or kidney problems
• if you suffer from Crohn’s disease or ulcerative colitis.
If you are not sure, talk to your doctor or pharmacist.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any medicines, including medicines obtained
without a prescription, in particular any other drug that has been prescribed to treat your blood pressure or any heart
condition that you have, such as digitoxin.
Do not take this medicine if any of the above applies to you. If you are not sure, talk to your doctor or pharmacist.
Diltiazem may inhibit the breakdown of certain medicines such as statins. This may lead to an increased and/or prolonged
effect of these medicines including an increased number and severity of side-effects, such as muscle weakness and
inflammation or liver infection.
Pregnancy and breast-feeding
You should not take this medicine if you are pregnant or are breast-feeding. Women of child-bearing potential should exclude
the possibility of pregnancy before commencing treatment. If it is at all possible that you could become pregnant while taking
this medicine you should use suitable contraception. You may wish to discuss this with your doctor.
Because diltiazem passes into breast milk, breast-feeding must be stopped while taking this medication.
Important information about some of the ingredients of Viazem® XL
The 120mg, 240mg and 300mg capsules contain azorubine (E122). Azorubine can cause allergic reactions including asthma.
Allergy is more common in those people allergic to aspirin.
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this
medicinal product.


Always take Viazem® XL exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not
sure. Viazem® XL capsules have been specially designed so that you only have to take your capsules once a day. However,
you must carry out the following steps to allow your medicine to work properly:
• You must take this medicine as prescribed by your doctor. Usually this will be one capsule to be taken at the same time
each day, preferably just before or during a meal.
• You should swallow the whole capsule, preferably with a glass of water. Do not bite, chew or suck the capsule otherwise
the medicine will not work properly.
• Do not stop taking this medicine before telling your doctor.
If you take more Viazem® XL than you should
Do not exceed the dose prescribed to you by your doctor. If you accidentally take more than the prescribed dose, seek
Please read the back of this leaflet.




medical advice immediately and take your medicine and this leaflet with you. Exceeding the correct dose may cause your
blood pressure to become too low and you may feel drowsy, dizzy, tired and/or confused. You could also find that your
heartbeats become irregular.
If you forget to take Viazem® XL
If you forget to take a dose, take it as soon as you remember then take the next one the following day, making sure that you
leave at least a twelve hour period between the two. Do not take a double dose to make up for a forgotten capsule.
Do not give Viazem® XL to children.


Like all medicines, Viazem® XL can cause side-effects, although not everybody gets them.
Allergic skin rashes may range in severity from mild to itchy skin eruptions to a rarer serious condition
called Stevens-Johnson syndrome, which may cause fever, chills, ulceration of the mouth, lips or skin.
If you experience symptoms suggestive of Stevens-Johnson syndrome, please consult your doctor or go
to your nearest hospital casualty department immediately.
Although most people do not have any problems using this medicine, a number of side-effects may
occasionally occur, including:
• leg or ankle swelling
• dizziness
• vomiting
• headache
• stomach upset
• constipation
• flushing
• diarrhoea
• skin rash
• tiredness
• nausea (a feeling of sickness)
Important information about your medicine
You may find what appears to be a capsule shell in the toilet. Do not be concerned, as this outer shell
does not have to be digested by the body. It does not mean that your medicine is not working.
If any of the side-effects get serious, or if you notice any side-effects not listed in this leaflet, please tell your doctor
or pharmacist.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this
leaflet. You can also report side effects directly via the Yellow Card Scheme at:
By reporting side effects you can help provide more information on the safety of this medicine.


Keep this medicine out of the sight and reach of children.
Do not take Viazem® XL after the expiry date on the carton. The expiry date is printed on one of the cardboard carton flaps
and on the foil blister pack. The expiry date refers to the last day of the month.
Do not store above 25ºC.
Store in original package and in a dry place away from any heat source, e.g. direct sunlight, heaters, steam, etc.
Return all unused capsules to your pharmacist. Only keep them if your doctor tells you to. Medicines should not be disposed
of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures
will help to protect the environment.

What Viazem® XL contains
The active substance in Viazem® XL prolonged release capsules is diltiazem hydrochloride.The other ingredients are sucrose
stearate, microcrystalline cellulose (E460), polyvidone, magnesium stearate, talc, methyl hydroxypropylcellulose, polysorbate
80, polyacrylate dispersion and simethicone emulsion.The gelatin capsules contain the following colouring agents: Lavender
opaque contains the colourants azorubine (E122), indigotine (E132) and titanium dioxide (E171), white opaque consists of
titanium dioxide (E171) and blue green opaque contains quinoline yellow (E104), indigotine (E132) and titanium dioxide
(E171).The white printing ink used in your medicine contains shellac, ethyl alcohol, isopropyl alcohol, n-butyl, propylene
glycol, sodium hydroxide, polyvinylpyrrolidone and titanium dioxide.The black printing ink contains shellac, ethyl alcohol,
isopropyl alcohol, n-butyl, propylene glycol, ammonium hydroxide, potassium hydroxide and black iron oxide.
What Viazem® XL looks like and contents of the pack
Viazem® XL prolonged release capsules are available in five different strengths to help your doctor to prescribe the right
amount of diltiazem to lower your blood pressure or control your angina; 120mg, 180mg, 240mg, 300mg and 360mg.
Capsule body
Capsule cap
120mg capsule
Lavender opaque
Lavender opaque
180mg capsule
White opaque
Blue green opaque
240mg capsule
Blue green opaque
Lavender opaque
300mg capsule
White opaque
Lavender opaque
360mg capsule
Blue green opaque
Blue green opaque
Each pack contains 28 capsules.
PL 00240/0375
Viazem® XL 120mg Capsules
PL 00240/0376
Viazem® XL 180mg Capsules
PL 00240/0377
Viazem® XL 240mg Capsules
PL 00240/0378
Viazem® XL 300mg Capsules
PL 00240/0379
Viazem® XL 360mg Capsules
Marketing Authorisation Holder:
Thornton & Ross Ltd., Linthwaite, Huddersfield, HD7 5QH, UK.
SMB Galephar SA, Rue de la Pirire 39, 6900 Marche-en-Famenne, Belgium.
Thornton & Ross Ltd., Linthwaite, Huddersfield, HD7 5QH, UK.
This leaflet was last revised in October 2015



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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.