REQUIP 1MG

Active substance: ROPINIROLE HYDROCHLORIDE

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2
10000000111418
GSK-ESP-Aranda-ESARA
United Kingdom-GBR

Package Leaflet: Information for the User

Requip
1

1 mg, 2 mg, 5 mg film-coated tablets
ropinirole (as the hydrochloride)
Read right through this leaflet before you start
taking these tablets.
This medicine has been prescribed for you
personally. Don’t pass it on to other people - it
may harm them even if their symptoms seem to
be the same as yours.

K

Keep this leaflet. You may need to read it again.
02-01-XX-273-11

If you have any more questions, ask your doctor
or pharmacist (chemist).
If you have serious side effects, or if you notice
any side effects not listed in this leaflet, tell
your doctor or pharmacist.
In this leaflet
1 What ReQuip is and what it is used for

1 What ReQuip is and what it is used for

2 Before you take ReQuip

ReQuip is used to treat Parkinson’s disease.

Don’t take ReQuip:

The active ingredient in ReQuip is ropinirole,
which belongs to a group of medicines called
dopamine agonists. Dopamine agonists affect
the brain in a similar way to a natural substance
called dopamine.

• if you’re allergic (hypersensitive) to ropinirole
or any of the other ingredients of ReQuip
(see Section 5 and 7)

People with Parkinson’s disease have low levels
of dopamine in some parts of their brains.
Ropinirole has effects similar to those of natural
dopamine, so it helps to reduce the symptoms
of Parkinson’s disease.

• if you have serious kidney disease
• if you have liver disease
➔ Tell your doctor if you think any of these may
apply to you.

Take special care with ReQuip
Your doctor needs to know before you take
ReQuip:

2 Before you take ReQuip

• if you are pregnant or think you may be
pregnant

3 While you’re taking ReQuip

• if you are breast-feeding

4 How to take ReQuip

• if you are under 18 years old

5 Possible side effects

• if you have a serious heart complaint

6 How to store ReQuip

• if you have a serious mental health problem

7 Further information

• if you have experienced any unusual urges
and/or behaviours (such as excessive
gambling or excessive sexual behaviour)

Tell your doctor if you or your family/carer notices
that you are developing urges or cravings to
behave in ways that are unusual for you and you
cannot resist the impulse, drive or temptation to
carry out certain activities that could harm
yourself or others. These are called impulse
control disorders and can include behaviours such
as addictive gambling, excessive eating or
spending, an abnormally high sex drive or an
increase in sexual thoughts or feelings. Your
doctor may need to adjust or stop your dose.
➔ Tell your doctor if you think any of these may
apply to you. Your doctor may decide that
ReQuip isn’t suitable for you or that you need
extra check-ups while you’re taking it.
You also need to be careful with ReQuip if you
drive or operate machinery. Please read the
warning in Section 3 of this leaflet.

ReQuip contains lactose
ReQuip tablets contain a small amount of a
sugar called lactose. If you have an intolerance
to lactose or any other sugars, ask your doctor
for advice before you take ReQuip.

• if you have an intolerance to some sugars
(such as lactose).
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HORIZONTAL SCALE: 100%

Page 1 of 4

PHARMA CODE N° 4358

SIDE 1

2
10000000111418
GSK-ESP-Aranda-ESARA
United Kingdom-GBR
Requip
1

Other medicines and ReQuip
Tell your doctor or pharmacist if you’re taking,
or have recently taken, any other medicines
including any herbal remedies or other
medicines you bought without a prescription.
Some medicines can affect the way ReQuip
works or make it more likely that you’ll have
side effects. ReQuip can also affect the way
some other medicines work.
These include:
• the anti-depressant fluvoxamine
• HRT (hormone replacement therapy)

K

• the antibiotics ciprofloxacin or enoxacin
• medication for other mental health
problems, for example sulpiride

02-01-XX-273-11

• metoclopramide, which is used to treat
nausea and heartburn
• cimetidine, used in the treatment of stomach
ulcers
• any other medicine for Parkinson’s disease.
➔ Tell your doctor if you’re taking, or have
recently taken, any of these.
Remember to tell your doctor if you start taking
any other medicine while you’re taking ReQuip.

• if you’re breast-feeding or planning to
breast-feed.
Your doctor may advise you to stop taking
ReQuip.

Children
Do not give ReQuip to children. ReQuip is not
normally prescribed for people under 18.

3 While you’re taking ReQuip
If you drive or operate machinery
ReQuip can make you feel drowsy. It can make
people feel extremely sleepy and it sometimes
makes people fall asleep very suddenly without
warning.
If you could be affected: don’t drive, don’t
operate machines and don’t put yourself in any
situation where feeling sleepy or falling asleep
could put you (or other people) at risk of serious
injury or death. Don’t take part in these
activities until you are no longer affected.
➔ Talk to your doctor if this causes problems for
you.

4 How to take ReQuip
Always take ReQuip exactly as your doctor has
told you to. Check with your doctor or
pharmacist if you’re not sure.
You may be given ReQuip on its own to treat
the symptoms of your Parkinson’s disease.
Or you may be given ReQuip as well as another
medicine called L-dopa (also called levodopa).
If you are taking L-dopa you may experience
some uncontrollable movements (dyskinesias)
when you first start taking ReQuip. Tell your
doctor if this happens, as your doctor may need
to adjust the dose of the medicines you are
taking.

Tell your doctor or nurse if you start smoking, or
give up smoking, while you’re taking ReQuip.
Your doctor or nurse may need to adjust your
dose.

Tell your doctor if you or your family notices
that you are developing any unusual behaviours
(such as an unusual urge to gamble or increased
sexual urges and/or behaviours) while you are
taking ReQuip. Your doctor may need to adjust
or stop your dose.

Food and drink with ReQuip

How much ReQuip will you need to take?

If you take ReQuip with food, you may be less
likely to feel sick or be sick (vomit). So it’s best
to take it with food if you can.

It may take a while to find out the best dose of
ReQuip for you.

Smoking and ReQuip

Pregnancy and breast-feeding
ReQuip is not recommended if you are
pregnant, unless your doctor advises that the
benefit to you taking ReQuip is greater than the
risk to your unborn baby. ReQuip is not
recommended if you are breast-feeding, as it
can affect your milk production.
Tell your doctor immediately:
• if you’re pregnant, if you think you might be
pregnant or if you’re planning to become
pregnant

The usual starting dose is 0.25 mg of ropinirole
three times each day for the first week. Then
your doctor will increase your dose each week,
for the next three weeks. After that, your
doctor will gradually increase the dose until you
are taking the dose that is best for you. The
usual is 1 mg to 3 mg three times each day
(making a total daily dose of 3 mg to 9 mg).
If your Parkinson’s disease symptoms have not
improved enough, your doctor may decide to
gradually increase your dose some more.
Some people take up to 8 mg of ReQuip three
times a day (24 mg daily altogether).
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2
10000000111418
GSK-ESP-Aranda-ESARA
United Kingdom-GBR

If you are also taking other medicines for
Parkinson’s disease, your doctor may advise you
to gradually reduce the dose of the other
medicine.
Don’t take any more ReQuip than your doctor
has recommended.

Requip
1

It may take a few weeks for ReQuip to work for
you.

Taking your dose of ReQuip
Take ReQuip three times a day.
Swallow your ReQuip tablets whole, with a
glass of water. It’s best to take ReQuip with
food, because that makes it less likely that you’ll
feel sick (nauseous).

K

If someone takes too much ReQuip
02-01-XX-273-11

Contact a doctor or pharmacist immediately.
If possible, show them the ReQuip pack.
Someone who has taken an overdose of
ReQuip may have any of these symptoms:
feeling sick (nausea), being sick (vomiting),
dizziness (a spinning sensation), feeling
drowsy, mental or physical tiredness, fainting,
hallucinations.

If you forget to take ReQuip
Don’t take extra tablets or a double dose to
make up for a missed dose. Just take your next
dose at the usual time.
If you have missed taking ReQuip for more than
a few days, ask your doctor for advice on how
to start taking it again.

If you suddenly stop taking ReQuip your
Parkinson’s disease symptoms may quickly get
much worse.
If you need to stop taking ReQuip your doctor
will reduce your dose gradually.
If you have any further questions on the use of
this product, ask your doctor or pharmacist.

5 Possible side effects
Like all medicines, ReQuip can have side effects,
but not everyone gets them.
The side effects of ReQuip are more likely to
happen when you first start taking it, or when
your dose has just been increased. They are
usually mild, and may become less troublesome
after you have taken the dose for a while.
If you’re worried about side effects, talk to your
doctor.

Very common side effects
These may affect more than 10 in 100 people
taking ReQuip:
• fainting
• feeling drowsy
• feeling sick (nausea)

Common side effects
These may affect more than 1 in 100 people
taking ReQuip:
• hallucinations (sensing things that are not
real)

• feeling very sleepy during the day (extreme
somnolence)
• falling asleep very suddenly without feeling
sleepy first (sudden sleep onset episodes)
• mental problems such as delirium (severe
confusion), delusions (unreasonable ideas) or
paranoia (unreasonable suspicions)

You may experience the following side
effects:
• inability to resist the impulse, drive or
temptation to perform an action that could be
harmful to you or others, which may include:
• trong impulse to gamble excessively despite
s
serious personal or family consequences
• ltered or increased sexual interest and
a
behaviour of significant concern to you or to
others, for example, an increased sexual drive
• ncontrollable excessive shopping or spending
u
• inge eating (eating large amounts of food
b
in a short time period) or compulsive eating
(eating more food than normal and more
than is needed to satisfy your hunger)

• feeling dizzy (a spinning sensation)

➔ Tell your doctor if you experience any of
these behaviours; they will discuss ways of
managing or reducing the symptoms

• heartburn

Very rare side effects

• stomach pain

A very small number of people taking ReQuip
(less than 1 in 10,000) have had:

• being sick (vomiting)

• swelling of the legs

Uncommon side effects

Don’t stop taking ReQuip without advice

These may affect more than 1 in 1,000 people
taking ReQuip:

Take ReQuip for as long as your doctor
recommends. Don’t stop unless your doctor
advises you to.

• feeling dizzy or faint, especially when you
stand up suddenly (this is caused by a drop in
blood pressure)

• changes in liver function, which have shown
up in blood tests
• allergic reactions such as red, itchy swellings
on the skin (hives), swelling of the face, lips,
mouth, tongue or throat which may cause
difficulty in swallowing or breathing, rash or
intense itching
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PHARMA CODE N° 4358

10000000111418
GSK-ESP-Aranda-ESARA
United Kingdom-GBR
Requip
1

If you’re taking ReQuip with L-dopa
People who are taking ReQuip with L-dopa may
develop other side effects over time:
• uncontrollable movements (dyskinesias) are a
very common side effect. Tell your doctor if
this happens, as your doctor may need to
adjust the doses of the medicines you are
taking
• feeling confused is a common side effect

If you get side effects
If you notice any unwanted effects (even ones
not mentioned in this leaflet) or if any of the
side effects becomes troublesome while you’re
taking ReQuip

K

6 How to store ReQuip

7 Further information
What ReQuip contains
The active substance in ReQuip is ropinirole
(as the hydrochloride) as 1 mg, 2 mg or 5 mg
tablets.

Don’t use ReQuip after the expiry date shown
on the carton.
Don’t store ReQuip above 25°C. Keep in a dry
place, away from light.
If you have any unwanted ReQuip tablets, don’t
dispose of them in waste water or household
rubbish. Take them back to your pharmacist,
who will dispose of them in a way that won’t
harm the environment.

The Manufacturer is Glaxo Wellcome S.A.,
Avendia de Extremadura 3, 09400 Aranda de
Duero, Burgos, Spain

The other ingredients are:

Keep ReQuip out of the sight and reach of
children.

The Marketing Authorisation Holder is
GlaxoSmithKline UK, Stockley Park West,
Uxbridge, Middlesex UB11 1BT

A number of groups exist to provide further
information and support to Parkinson’s disease
patients and their carers. The main one is
Parkinson’s UK, who you can contact at the
address given below:

• tablet cores: lactose monohydrate,
microcrystalline cellulose, croscarmellose
sodium, magnesium stearate
• film coats:
1 mg tablet: hypromellose, macrogol
400, titanium dioxide (E171), iron oxide
yellow (E172), indigo carmine aluminium
(E132).

➔ Tell your doctor or pharmacist.

2 mg tablet: hypromellose, macrogol
400, titanium dioxide (E171), iron oxide
yellow (E172), iron oxide red (E172).

02-01-XX-273-11

5 mg tablet: hypromellose, macrogol
400, titanium dioxide (E171), indigo carmine
aluminium (E132), polysorbate 80 (E433).

What ReQuip looks like and contents of the
pack

Parkinson’s UK
215 Vauxhall Bridge Road
London SW1V 1EJ
Other formats:
To listen to or request a copy of this leaflet in
Braille, large print or audio please call, free of
charge:

0800 198 5000 (UK Only)
Please be ready to give the following information:
Product name

ReQuip 1 mg
ReQuip 2 mg
ReQuip 5 mg

ReQuip (all strengths) is provided as pentagonal,
film-coated tablets, marked ‘SB’ on one side.

Reference number 10592/0087

ReQuip 1 mg: green tablets marked ‘4892’ on
reverse side.

This is a service provided by the Royal National
Institute of Blind People.

ReQuip 2 mg: pink tablets marked ‘4893’ on
reverse side.

Leaflet date: November 2012

ReQuip 5 mg: blue tablets marked ‘4894’ on
reverse side.

ReQuip and the ReQuip tablet shape are
registered trademarks of the GlaxoSmithKline
group of companies

All strengths are supplied in blister packs of
84 tablets.

© 2012 GlaxoSmithKline group of companies.
All rights reserved

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Page 4 of 4

3
CLB-P-708-750-13844
Pharma Code Ref. No. 2845

1

ropinirole (as the hydrochloride)

0.25 mg, 0.5 mg, 1 mg film-coated tablets

Package Leaflet: Information for the User
Starter Pack

Read right through this leaflet before
you start taking these tablets.
This medicine has been prescribed for you
personally. Don’t pass it on to other
people - it may harm them even if their
symptoms seem to be the same as yours.
Keep this leaflet. You may need to read it
again.
If you have any more questions, ask your
doctor or pharmacist (chemist).
If you have serious side effects, or if
you notice any side effects not listed in
this leaflet, tell your doctor or
pharmacist.

In this leaflet
1 What ReQuip is and what it is used
for
2 Before you take ReQuip
3 While you’re taking ReQuip
4 How to take ReQuip
5 Possible side effects
6 How to store ReQuip
7 Further information

What ReQuip is and what it is
used for

ReQuip is used to treat Parkinson’s
disease.
The active ingredient in ReQuip is ropinirole,
which belongs to a group of medicines
called dopamine agonists. Dopamine
agonists affect the brain in a similar way to
a natural substance called dopamine.
People with Parkinson’s disease have low
levels of dopamine in some parts of their
brains. Ropinirole has effects similar to
those of natural dopamine, so it helps to
reduce the symptoms of Parkinson’s
disease.

2

Before you take ReQuip

Don’t take ReQuip:
• if you’re allergic (hypersensitive) to
ropinirole or any of the other
ingredients of ReQuip (see Section 5
and 7)
• if you have serious kidney disease
• if you have liver disease
➔ Tell your doctor if you think any of
these may apply to you.
Take special care with ReQuip
Your doctor needs to know before you take
ReQuip:
• if you are pregnant or think you may
be pregnant
• if you are breast-feeding
• if you are under 18 years old
• if you have a serious heart
complaint
• if you have a serious mental health
problem
• if you have experienced any unusual
urges and/or behaviours (such as
excessive gambling or excessive sexual
behaviour)
• if you have an intolerance to some
sugars (such as lactose).
Tell your doctor if you or your family/carer
notices that you are developing urges or

cravings to behave in ways that are unusual
for you and you cannot resist the impulse,
drive or temptation to carry out certain
activities that could harm yourself or others.
These are called impulse control disorders
and can include behaviours such as
addictive gambling, excessive eating or
spending, an abnormally high sex drive or
an increase in sexual thoughts or feelings.
Your doctor may need to adjust or stop your
dose.
➔ Tell your doctor if you think any of
these may apply to you. Your doctor
may decide that ReQuip isn’t suitable
for you or that you need extra
check-ups while you’re taking it.
You also need to be careful with ReQuip if
you drive or operate machinery. Please
read the warning in Section 3 of this
leaflet.
ReQuip contains lactose
ReQuip tablets contain a small amount of a
sugar called lactose. If you have an
intolerance to lactose or any other sugars,
ask your doctor for advice before you take
ReQuip.
Other medicines and ReQuip
Tell your doctor or pharmacist if you’re
taking, or have recently taken, any
other medicines - including any herbal
remedies or other medicines you bought
without a prescription.
Some medicines can affect the way ReQuip
works or make it more likely that you’ll
have side effects. ReQuip can also affect the
way some other medicines work.
These include:
• the anti-depressant fluvoxamine
• HRT (hormone replacement therapy)
• the antibiotics ciprofloxacin or
enoxacin
• medication for other mental health
problems, for example sulpiride
• metoclopramide, which is used to
treat nausea and heartburn
• cimetidine, used in the treatment of
stomach ulcers

any other medicine for Parkinson’s
disease.
➔ Tell your doctor if you’re taking, or
have recently taken, any of these.
Remember to tell your doctor if you start
taking any other medicine while you’re
taking ReQuip.
Pregnancy and breast-feeding
ReQuip is not recommended if you are
pregnant, unless your doctor advises that
the benefit to you taking ReQuip is greater
than the risk to your unborn baby. ReQuip
is not recommended if you are
breast-feeding, as it can affect your milk
production.
Tell your doctor immediately:
• if you’re pregnant, if you think you
might be pregnant or if you’re planning
to become pregnant
• if you’re breast-feeding or planning to
breast-feed.
Your doctor may advise you to stop taking
ReQuip.
Children
Do not give ReQuip to children. ReQuip is
not normally prescribed for people under
18.


3 While you’re taking ReQuip
If you drive or operate machinery
ReQuip can make you feel drowsy. It can
make people feel extremely sleepy and
it sometimes makes people fall asleep
very suddenly without warning.
If you could be affected: don’t drive, don’t
operate machines and don’t put yourself
in any situation where feeling sleepy or
falling asleep could put you (or other
people) at risk of serious injury or death.
Don’t take part in these activities until you
are no longer affected.
➔ Talk to your doctor if this causes
problems for you.
Smoking and ReQuip
Tell your doctor or nurse if you start
smoking, or give up smoking, while you’re

taking ReQuip. Your doctor or nurse may
need to adjust your dose.
Food and drink with ReQuip
If you take ReQuip with food, you may
be less likely to feel sick or be sick
(vomit). So it’s best to take it with food if
you can.

CLB-P-708-750-13844

GSK-ContractMfg-Eur-UK-United Kingdom-Catalent-Bolton

United Kingdom-GBR
Requip
1

4 How to take ReQuip
Always take ReQuip exactly as your
doctor has told you to. Check with your
doctor or pharmacist if you’re not sure.
You may be given ReQuip on its own to
treat the symptoms of your Parkinson’s
disease. Or you may be given ReQuip as
well as another medicine called L-dopa
(also called levodopa).
If you are taking L-dopa you may
experience some uncontrollable movements
(dyskinesias) when you first start taking
ReQuip. Tell your doctor if this happens, as
your doctor may need to adjust the dose of
the medicines you are taking.
Tell your doctor if you or your family notices
that you are developing any unusual
behaviours (such as an unusual urge to
gamble or increased sexual urges and/or
behaviours) while you are taking ReQuip.
Your doctor may need to adjust or stop your
dose.
How much ReQuip will you need to
take?
It may take a while to find out the best
dose of ReQuip for you. The usual starting
dose is 0.25 mg three times a day for the
first week. This dose is then gradually
increased each week.
The ReQuip Starter Pack contains four
blister strips of tablets - one strip for each
of the first four weeks of your treatment.
The four strips are marked with Week 1,
Week 2, Week 3 and Week 4, and also
with the treatment day
(Day 1 to Day 28).
You must take the tablets
in the order of the day

K

CLG434

FRONT
PAGE 1 OF 2

3
number printed on the strips, starting at
Day 1 and finishing at Day 28. The daily
dose you take of ReQuip increases each
week. There is one tablet in each blister
pocket for you to take during Weeks 1, 2
and 4, and two tablets for you to take
during Week 3.
Week 1 Week 2 Week 3 Week 4
Morning 0.25 mg 0.5 mg 0.75 mg 1 mg
(about 1 white 1 pale 1 white 1 green
8 am) tablet yellow tablet tablet
tablet 1 pale
yellow
tablet
After 0.25 mg 0.5 mg 0.75 mg 1 mg
lunch 1 white 1 pale 1 white 1 green
(about tablet yellow tablet tablet
tablet 1 pale
1 pm)
yellow
tablet
Evening 0.25 mg 0.5 mg 0.75 mg 1 mg
(about 1 white 1 pale 1 white 1 green
6 pm) tablet yellow tablet tablet
tablet 1 pale
yellow
tablet
Keep taking ReQuip until you have finished
this four-week Starter Pack. After that, your
doctor may gradually increase or decrease
the dose until you’re taking what’s best for
you. Some people take up to 8 mg of
ReQuip three times a day (24 mg daily
altogether).
If you are also taking other medicines for
Parkinson’s disease, your doctor may
advise you to gradually reduce the dose of
the other medicine.
Don’t take any more ReQuip than your
doctor has recommended.
It may take a few weeks for ReQuip to
work for you.
Taking your dose of ReQuip
Take ReQuip three times a day.

Swallow your ReQuip tablet(s) whole,
with a glass of water. It’s best to take
ReQuip with food, because that makes it
less likely that you’ll feel sick (nauseous).
If someone takes too much ReQuip
Contact a doctor or pharmacist
immediately. If possible, show them the
ReQuip pack.
Someone who has taken an overdose of
ReQuip may have any of these symptoms:
feeling sick (nausea), being sick (vomiting),
dizziness (a spinning sensation), feeling
drowsy, mental or physical tiredness,
fainting, hallucinations.
If you forget to take ReQuip
Don’t take extra tablets or a double
dose to make up for a missed dose.
Just take your next dose at the usual time.
If you have missed taking ReQuip for
more than a few days, ask your doctor
for advice on how to start taking it again.
Don’t stop taking ReQuip without
advice
Take ReQuip for as long as your doctor
recommends. Don’t stop unless your
doctor advises you to.
If you suddenly stop taking ReQuip your
Parkinson’s disease symptoms may quickly
get much worse.
If you need to stop taking ReQuip your
doctor will reduce your dose gradually.
If you have any further questions on the
use of this product, ask your doctor or
pharmacist.

5 Possible side effects
Like all medicines, ReQuip can have side
effects, but not everyone gets them.
The side effects of ReQuip are more likely
to happen when you first start taking it, or
when your dose has just been increased.
They are usually mild, and may become
less troublesome after you have taken the
dose for a while.
If you’re worried about side effects, talk to
your doctor.

Very common side effects
These may affect more than 10 in 100
people taking ReQuip:
• fainting
• feeling drowsy
• feeling sick (nausea)
Common side effects
These may affect more than 1 in 100
people taking ReQuip:
• hallucinations (sensing things that are
not real)
• being sick (vomiting)
• feeling dizzy (a spinning sensation)
• heartburn
• stomach pain
• swelling of the legs
Uncommon side effects
These may affect more than 1 in 1,000
people taking ReQuip:
• feeling dizzy or faint, especially when
you stand up suddenly (this is caused
by a drop in blood pressure)
• feeling very sleepy during the day
(extreme somnolence)
• falling asleep very suddenly without
feeling sleepy first (sudden sleep
onset episodes)
• mental problems such as delirium
(severe confusion), delusions
(unreasonable ideas) or paranoia
(unreasonable suspicions)
You may experience the following side
effects:
• inability to resist the impulse, drive or
temptation to perform an action that
could be harmful to you or others,
which may include:
• strong impulse to gamble
excessively despite serious
personal or family consequences.
• altered or increased sexual
interest and behaviour of
significant concern to you or to
others, for example, an increased
sexual drive.
• uncontrollable excessive
shopping or spending



binge eating (eating large amounts
of food in a short time period) or
compulsive eating (eating more
food than normal and more than is
needed to satisfy your hunger)
➔ Tell your doctor if you experience
any of these behaviours; they will
discuss ways of managing or
reducing the symptoms
Very rare side effects
A very small number of people taking
ReQuip (less than 1 in 10,000) have had:
• changes in liver function, which have
shown up in blood tests
• allergic reactions such as red, itchy
swellings on the skin (hives), swelling
of the face, lips, mouth, tongue or
throat which may cause difficulty in
swallowing or breathing, rash or
intense itching
If you’re taking ReQuip with L-dopa
People who are taking ReQuip with L-dopa
may develop other side effects over time:
• uncontrollable movements
(dyskinesias) are a very common side
effect. Tell your doctor if this happens,
as your doctor may need to adjust the
doses of the medicines you are taking
• feeling confused is a common side
effect
If you get side effects
If you notice any unwanted effects
(even ones not mentioned in this leaflet)
or if any of the side effects becomes
troublesome while you’re taking ReQuip
➔ Tell your doctor or pharmacist.

6 How to store ReQuip
Keep ReQuip out of the sight and reach of
children.
Don’t use ReQuip after the expiry date
shown on the carton.
Don’t store ReQuip above 25°C. Keep in a
dry place, away from light.
If you have any unwanted ReQuip tablets,
don’t dispose of them in waste water or

household rubbish. Take them back to your
pharmacist, who will dispose of them in a
way that won’t harm the environment.

7 Further information
What ReQuip contains
The active substance in the ReQuip
Starter Pack is ropinirole (as the
hydrochloride) as 0.25 mg, 0.5 mg and
1 mg tablets.
The other ingredients are:
• tablet cores: lactose monohydrate,
microcrystalline cellulose,
croscarmellose sodium, magnesium
stearate
• film coats:
0.25 mg tablet: hypromellose,
macrogol 400, titanium dioxide (E171),
polysorbate 80 (E433).
0.5 mg tablet: hypromellose, macrogol
400, titanium dioxide (E171), iron oxide
yellow (E172), iron oxide red (E172),
indigo carmine aluminium (E132).
1 mg tablet: hypromellose, macrogol 400,
titanium dioxide (E171), iron oxide yellow
(E172), indigo carmine aluminium (E132).
What ReQuip looks like and contents
of the pack
ReQuip (all strengths) is provided as
pentagonal, film-coated tablets, marked
‘SB’ on one side.
ReQuip 0.25 mg: white tablets marked
‘4890’ on reverse side.
ReQuip 0.5 mg: pale yellow tablets
marked ‘4891’ on reverse side.
ReQuip 1 mg: green tablets marked
‘4892’ on reverse side.
0.25 mg, 0.5 mg and 1 mg tablets are
supplied in a Starter blister pack of 105
tablets.
The Marketing Authorisation Holder is
GlaxoSmithKline UK, Stockley Park West,
Uxbridge, Middlesex UB11 1BT
The Manufacturer is Catalent UK
Packaging Limited, Lancaster Way,
Wingates Industrial Estate, Westhoughton,
Bolton, Lancashire BL5 3XX

A number of groups exist to provide
further information and support to
Parkinson’s disease patients and their
carers. The main one is Parkinson’s UK,
who you can contact at the address given
below:
Parkinson’s UK
215 Vauxhall Bridge Road
London SW1V 1EJ
Other formats:
To listen to or request a copy of this leaflet
in Braille, large print or audio please call,
free of charge:

0800 198 5000 (UK Only)

Please be ready to give the following
information:
Product name
ReQuip 0.25 mg
ReQuip 0.5 mg
ReQuip 1 mg
Reference number
10592/0085
This is a service provided by the Royal
National Institute of Blind People.
Leaflet date: November 2012
ReQuip and the ReQuip tablet shape are
registered trademarks of the
GlaxoSmithKline group of companies
© 2012 GlaxoSmithKline group of
companies. All rights reserved

CLB-P-708-750-13844
GSK-ContractMfg-Eur-UK-United Kingdom-Catalent-Bolton

United Kingdom-GBR
Requip
1

K

CLG434

CLB-P-708-750-13844

Pharma Code Ref. No. 2845

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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