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Active substance: DIPYRIDAMOLE

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Persantin® Retard 200mg

Read all of this leaflet carefully
before you start taking this medicine.
Keep this leaflet. You may need to
read it again.
If you have any further questions, ask
your doctor or pharmacist.
This medicine has been prescribed for
you. Do not pass it on to others. It may
harm them, even if their symptoms are
the same as yours.
If any of the side effects gets
troublesome or serious, or if you
notice any side effects not listed in this
leaflet, please tell your doctor or
The name of your medicine is Persantin
Retard 200mg Capsules, but it will be
referred as Persantin Retard throughout
this leaflet.

In this leaflet:
1. What Persantin Retard is and what it is
used for
2. Before you take Persantin Retard
3. How to take Persantin Retard
4. Possible side effects
5. How to store Persantin Retard
6. Further information

The name of your medicine is Persantin
Retard. It contains a medicine called
Dipyridamole. This
belongs to a group of medicines called
‘anti-thrombotic agents’, which are used
to help stop blood clots forming.
Persantin Retard is used:
To help stop blood clots which may
occur if you have had your heart
valves replaced.
In people who have had a stroke
caused by a blood clot in the brain.
This medicine reduces the risk of
having another stroke.

Do not take Persantin Retard if you
are allergic (hypersensitive) to:
Any of the other ingredients of
Persantin Retard (see section 6:
Further Information)

Take special care with Persantin
Check with your doctor or pharmacist
before taking your medicine if:
You have angina or other heart
problems (including heart valve or
circulation problems) or have had a
recent heart attack
You have myasthenia gravis (a rare
muscle problem)
You have any bleeding problems

You are pregnant or planning to
become pregnant or are breastfeeding
If you are not sure if any of the above
apply to you, talk to your doctor or
pharmacist before taking Persantin

Taking other medicines
Please tell your doctor or pharmacist if
you are taking or have recently taken
any other medicines, including medicines
obtained without a prescription. This
includes herbal medicines. This is
because Persantin Retard can affect the
way some other medicines work. Also
some other medicines can affect the way
Persantin Retard works.
In particular, tell your doctor or
pharmacist if you are taking any of the
following medicines:
Medicines for high blood pressure
Medicines for muscle weakness such
as something called a ‘cholinesterase
Aspirin (or planning to take aspirin for
any condition)
Adenosine injection - used for heart
problems or tests on the heart
Warfarin or other medicines to stop
blood clots forming. If so, tell them at
your next visit to the anticoagulant
clinic that you are now taking
Persantin Retard

If you are having heart tests
Persantin Retard contains
dipyridamole. Dipyridamole is also
sometimes given as an injection during
tests to see if the heart is working
properly (also called ‘myocardial
imaging’). This means that the test and
your medicine may contain the same
substance. If you are going to have an
injection of dipyridamole, tell the doctor
that you are taking Persantin Retard.

Pregnancy and breast-feeding
Tell your doctor if you are pregnant or
planning to get pregnant.
Tell your doctor if you are breastfeeding as Persantin Retard should
only be used during breast-feeding if
your doctor considers it essential.
Driving and using machines
You may feel dizzy while taking Persantin
Retard. If this happens do not drive or use
any tools or machines.

Always take this medicine exactly as
your doctor has told you. You should
check with your doctor or pharmacist if
you are not sure.

The usual dose is:
One capsule twice a day
Usually one in the morning and one in
the evening
It is best to take it with food
Swallow the capsule whole
Do not crush or chew it

Do not give to children.

If you take more Persantin Retard
than you should
If you take more of this medicine than
you should, talk to a doctor or go to a
hospital straight away. Take the
medicine pack with you, even if there
are no capsules left.

If you forget to take Persantin Retard
If you forget a dose, take it as soon as
you remember it
However, if it is time for the next dose,
skip the missed dose
Do not take a double dose to make up
for the forgotten dose
If you have any further questions on the
use of this product, ask your doctor or

Like all medicines Persantin Retard
can cause side effects, although not
everybody gets them.

Allergic reactions
If you have an allergic reaction, stop
taking your medicine and see a doctor
straight away. The signs may include
feeling breathless, runny nose, severe
rash with itching, swelling and swelling
around the eyes.
Other side effects that have been reported
for Persantin Retard are described below.
They are listed as either very common,
common, or not known.

Very common (affects more than 1 in 10
Feeling dizzy
Feeling sick (nausea)

Common (affects less than 1 in 10
people but more than 1 in 100 people)
Muscle pain
Being sick (vomiting)
Worsening of the symptoms of heart
disease such as chest pain and
shortness of breath

Not Known
Hot flushes
Lowering of blood pressure or
increased heart rate
A blood problem called
‘thrombocytopenia’ which can cause
bruising and prolonged bleeding from
wounds, including during or after
In people who have gallstones, the
dipyridamole in this medicine can be
absorbed into the gallstones.

Reporting side effects
If you get any side effects, talk to your
doctor, pharmacist or nurse. This includes
any possible side effects not listed in this
leaflet. You can also report side effects
directly via the Yellow Card Scheme

By reporting side effects, you can help
provide more information on the safety of
this medicine

Keep out of the sight and reach of
Store between 15°C - 25°C. Protect from
Do not take Persantin Retard after the
expiry date which is stated on the carton
and bottle label after ‘Exp’. The date refers
to the last day of that month.
Discard any capsules remaining 6 weeks
after first opening.
Medicines should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of medicines
that are no longer required. These
measures will help to protect the

What Persantin Retard contains
The active substance is dipyridamole.
Each modified release capsule contains
200mg of dipyridamole.
The other ingredients are: tartaric acid,
povidone, eudragit , talc, gum arabic,
hypromellose, hypromellose phthalate,
triacetin, dimethicone, stearic palmitic
acid, gelatin, titanium dioxide, red iron
oxide and yellow iron oxide.

What Persantin Retard looks like and
contents of the pack
Orange/ red hard gelatin modified release
capsules containing microgranules.
It is available in a white plastic bottle with
a child resistant screw cap and a
desiccator containing 60 capsules.
Manufactured by: Boehringer Ingelheim
Pharma GmbH & Co. KG, Birkendorfer
Strasse 65, D-88397 Biberach/Riss,
Procured from within the EU and
repackaged by the Product Licence
holder: B&S Healthcare, Unit 4,
Bradfield Road, Ruislip, Middlesex,
HA4 0NU, UK.
Persantin Retard 200mg Modified
Release Capsules – PL No: 18799/2213
Leaflet Date: 10.10.2014


Persentin Retard is a registered trademark
of Boehringer Ingelheim group of

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.