Active substance: DIPYRIDAMOLE

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Persantin Retard 200mg
Modified Release Hard

Read all of this leaflet carefully
before you start taking this medicine.

Keep this leaflet. You may need to
read it again.
If you have any further questions, ask
your doctor or pharmacist.
This medicine has been prescribed for
you. Do not pass it on to others. It may
harm them, even if their symptoms are
the same as yours.
If any of the side effects gets
troublesome or serious, or if you
notice any side effects not listed in this
leaflet, please tell your doctor or

The name of your medicine is Persantin
Retard 200mg Capsules, but it will be
referred as Persantin Retard throughout
this leaflet.

In this leaflet:
1. What PERSANTIN Retard is and what
it is used for
2. Before you take PERSANTIN Retard
3. How to take PERSANTIN Retard
4. Possible side effects
5. How to store PERSANTIN Retard
6. Further information

The name of your medicine is
PERSANTIN Retard. It contains a
medicine called Dipyridamole. This
belongs to a group of medicines called
‘anti-thrombotic agents’, which are used
to help stop blood clots forming.
PERSANTIN Retard is used:
 To help stop blood clots which may
occur if you have had your heart
valves replaced.
 In people who have had a stroke
caused by a blood clot in the brain.
This medicine reduces the risk of
having another stroke.

Do not take PERSANTIN Retard if you
are allergic (hypersensitive) to:

Any of the other ingredients of
PERSANTIN Retard (see section 6:
Further Information)

Take special care with PERSANTIN
Check with your doctor or pharmacist
before taking your medicine if:
 You have angina or other heart
problems (including heart valve or
circulation problems) or have had a
recent heart attack
 You have myasthenia gravis (a rare
muscle problem)
 You have any bleeding problems
 You are pregnant or planning to
become pregnant or are breastfeeding
If you are not sure if any of the above
apply to you, talk to your doctor or
pharmacist before taking PERSANTIN

Taking other medicines
Please tell your doctor or pharmacist if
you are taking or have recently taken
any other medicines, including
medicines obtained without a
prescription. This includes herbal
medicines. This is because PERSANTIN
Retard can affect the way some other
medicines work. Also some other
medicines can affect the way
PERSANTIN Retard works.
In particular, tell your doctor or
pharmacist if you are taking any of the
following medicines:
 Medicines for high blood pressure
 Medicines for muscle weakness such
as something called a ‘cholinesterase
 Aspirin (or planning to take aspirin for
any condition)
 Adenosine injection - used for heart
problems or tests on the heart
 Warfarin or other medicines to stop
blood clots forming. If so, tell them at
your next visit to the anticoagulant
clinic that you are now taking

If you are having heart tests
PERSANTIN Retard contains
dipyridamole. Dipyridamole is also
sometimes given as an injection during
tests to see if the heart is working
properly (also called ‘myocardial
imaging’). This means that the test and
your medicine may contain the same
substance. If you are going to have an
injection of dipyridamole, tell the doctor
that you are taking PERSANTIN Retard.

Pregnancy and breast-feeding

Tell your doctor if you are pregnant or
planning to get pregnant.
Tell your doctor if you are breastfeeding as PERSANTIN Retard should
only be used during breast-feeding if
your doctor considers it essential.

Always take this medicine exactly as
your doctor has told you. You should
check with your doctor or pharmacist if
you are not sure.
The usual dose is:
 One capsule twice a day
 Usually one in the morning and one in
the evening
 It is best to take it with food
 Swallow the capsule whole
 Do not crush or chew it
Do not give to children.

If you take more PERSANTIN Retard
than you should
If you take more of this medicine than
you should, talk to a doctor or go to a
hospital straight away. Take the
medicine pack with you, even if there
are no capsules left.

If you forget to take PERSANTIN

If you forget a dose, take it as soon as
you remember it
However, if it is time for the next dose,
skip the missed dose
Do not take a double dose to make up
for the forgotten dose

If you have any further questions on the
use of this product, ask your doctor or

Like all medicines PERSANTIN Retard
can cause side effects, although not
everybody gets them.

Allergic reactions
If you have an allergic reaction, stop
taking your medicine and see a doctor
straight away. The signs may include
feeling breathless, runny nose, severe
rash with itching, swelling and swelling
around the eyes.

Other side effects are:

Hot flushes
Lowering of blood pressure or
increased heart rate
Worsening of the symptoms of heart
disease such as chest pain and heart
beat problems
A blood problem called ‘thrombocytopenia’ which can cause bruising
and prolonged bleeding from wounds,
including during or after surgery

In people who have gallstones, the
dipyridamole in this medicine can be
absorbed into the gallstones.

The side effects listed below usually
go away as treatment continues:

Headache or feeling dizzy
Being sick (vomiting), feeling sick
(nausea), indigestion or diarrhoea
Muscle pain

If any of the side effects gets
troublesome or serious, or if you notice
any side effects not listed in this leaflet,
please tell your doctor or pharmacist.

Keep out of the sight and reach of
Store between 15°C - 25°C. Protect from
Do not take PERSANTIN Retard after the
expiry date which is stated on the carton
and bottle label after ‘Exp’. The date refers
to the last day of that month.
Discard any capsules remaining 6 weeks
after first opening.
Medicines should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of medicines
that are no longer required. These
measures will help to protect the

What PERSANTIN Retard contains
The active substance is dipyridamole.
Each modified release capsule contains
200mg of dipyridamole.
The other ingredients are: tartaric acid,
povidone, eudragit , talc, gum arabic,
hypromellose, hypromellose phthalate,
triacetin, dimethicone, stearic palmitic
acid, gelatin, titanium dioxide, red iron
oxide and yellow iron oxide.

What PERSANTIN Retard looks like
and contents of the pack
Orange/ red hard gelatin modified release
capsules containing microgranules.
It is available in a white plastic bottle with
a child resistant screw cap and a
desiccator containing 60 capsules.
Manufactured by: Boehringer Ingelheim
Pharma GmbH & Co. KG, Birkendorfer
Strasse 65, D-88397 Biberach/Riss,
Procured from within the EU and
repackaged by the Product Licence
holder: B&S Healthcare, Unit 4,
Bradfield Road, Ruislip, Middlesex,
HA4 0NU, UK.
Persantin Retard 200mg Modified
Release Capsules – PL No: 18799/2213
Leaflet Date: 15.07.2013
Persentin Retard is a registered trademark
of Boehringer Ingelheim group of

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.