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Midazolam

Generic name: midazolam (oral) [ mye-DAZ-oh-lam ]
Brand name: Versed
Dosage form: oral syrup (2 mg/mL)
Drug class: Benzodiazepines

Medically reviewed by Drugs.com on Aug 11, 2023. Written by Cerner Multum.

What is midazolam?

Midazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to help you relax before having a minor surgery, dental work, or other medical procedure.

Midazolam may also be used for purposes not listed in this medication guide.

Midazolam side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. Your caregivers will watch you for symptoms such as weak or shallow breathing.

Tell your medical caregivers right away if you have:

Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury.

Common side effects of midazolam may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. Midazolam is given in a hospital, dentist office, or other clinic setting where your vital signs can be watched closely.

Before taking this medicine

You should not use midazolam if you are allergic to it, or if you have:

Tell your doctor if you have ever had:

Tell your doctor if you are pregnant or breastfeeding.

How should I take midazolam?

Midazolam is usually given as a single dose just before your surgery or procedure.

Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. Midazolam should be used only in a hospital, dentist office, or other clinic setting where any serious side effects can be quickly treated.

After you take midazolam, you will be watched closely to make sure the medicine is working and does not cause harmful side effects.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are in surgery.

What happens if I miss a dose?

In a medical setting you are not likely to miss a dose.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid after taking midazolam?

Do not drink alcohol shortly after taking midazolam. midazolam can increase the effects of alcohol, which could be dangerous.

Grapefruit may interact with midazolam and cause side effects. Avoid consuming grapefruit products for a short time after taking midazolam.

You may feel drowsy for 24 to 48 hours after the injection. Avoid driving or hazardous activity until the effects of midazolam have worn off completely. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

What other drugs will affect midazolam?

Shortly after you are treated with midazolam, using other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect midazolam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Popular FAQ

For the first dose, use one 5 mg spray in one nostril. If the seizure cluster continues for at least 10 minutes after the first dose, a second 5 mg dose may be given if your healthcare provider has instructed you to give a second dose. Give the second dose in the other nostril. If the seizures do not stop after Nayzilam is used, get emergency medical help right away (call 911). DO NOT give more than 2 doses to treat a seizure cluster. Continue reading

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.