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J COLLIS BROWNES TABLETS

Active substance: MORPHINE HYDROCHLORIDE

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TEXT FOR NON-MARKETED PACKS
J. COLLIS BROWNE’S TABLETS LEAFLET
PL 00240/0092
 
 

J.Collis Browne’s Tablets
(morphine hydrochloride, light kaolin, calcium carbonate)
Important information about J.Collis Browne’s Tablets
• This medicine relieves the symptoms of diarrhoea in adults and children over 12 years.
Do not take….
• If you have breathing problems.
• Or give to children under 12 years.
• Avoid drinking alcohol while taking this medicine. See section 2.
Now read the rest of the leaflet before you use this medicine. It includes other information
which might be especially important for you.
• Keep this leaflet. You may need to read it again.
• Ask your pharmacist if you need any more information or advice.
• If you notice any side effects not listed in this leaflet please tell your doctor or pharmacist.
1. What the medicine is for
J.Collis Browne’s Tablets relieve the symptoms of occasional diarrhoea. The medicine contains
morphine which helps calm and reduce the effects of diarrhoea. They also contain kaolin which
helps remove toxic and other substances from the digestive system, and calcium carbonate which
helps increase the bulk of solid waste and neutralizes excess stomach acid.
2. Before you use this medicine
Do not use the medicine if you or your child have….
• An allergy to any of the ingredients listed in section 6.
• Shallow breath or breathing difficulties.
• A head injury or persistent headache.
• An asthma attack.
• Taken MAOIs (monoamine oxidase inhibitors) for depression within the last two weeks.
• A blocked intestine or inflammation of your colon or rectum.
• An addiction to alcohol.
• Liver or kidney disease.
• Heart failure.
• Fits or seizures.
• A coma.
• High levels of alkali in the blood.
• High levels of calcium in the blood.
• Reduced stomach acid.
• Phaeochromocytoma (a rare tumor of the adrenal glands).
• Severe abdominal pain.
• Or your child is under 12 years old.

TEXT FOR NON-MARKETED PACKS
J. COLLIS BROWNE’S TABLETS LEAFLET
PL 00240/0092
 
 

Talk to your doctor if you or your child have…
• Kidney or liver problems.
• High or low blood pressure.
• Prostate problems.
• An underactive thyroid gland.
• An addiction to drugs such as painkillers or morphine.
• A history of asthma.
• Heart problems.
• A low sodium diet.
• Problem associated with high calcium levels in the blood.
• Or are elderly, or weakened, as these people can react differently to the medicine and may eed a
lower dose.
Talk to your doctor or pharmacist if you or your child are taking….
• Any tranquillisers/sedatives (e.g. diazepam, lorazepam).
• Any antidepressants (e.g. MAOIs, SSRIs amitriptyline, tricyclics, moclobemide).
• Any sleeping tablets (e.g. temazepam, promethazine).
• Any medicine for mental illness (e.g. chlorpromazine, haloperidol, phenothiazines, sulpiride).
• Any medicine to treat epilepsy (e.g. carbamazepine, phenytoin, gabapentin).
• Any medicine for a heart problem (e.g. mexiletine, cardiac glycosides such as digoxin,
dipyridamole).
• Medicies for high blood pressure (e.g. esmolol, ACE inhibitors such as captopril,
enalapril,fosinopril).
• Medicines to thin the blood (e.g. warfarin).
• Alcohol.
• Aspirin.
• Cimetidine or lansoprazole for a stomach ulcer.
• Metoclopramide or domperidone for nausea and vomiting.
• Cisapride for gastric reflux.
•Antibiotics (e.g. rifampicin, ciprofloxacin, isoniazid, and other quinolones, cefaclor,
cefpodoxime, tetracyclines, azithromycin).
• Antifungals (e.g. itraconazole, ketoconazole).
• Antivirals (e.g. ritonavir, atazanavir, tipranavir, fosamprenavir).
• Antihistamines (e.g. sedating: promethazine, and non sedating: fexofenadine).
• Medicines to treat malaria (e.g. chloroquine, hydroxychloroquine).
• Sodium oxybate for daytime sleepiness.
• Baclofen a muscle relaxant.
• Bisphosponates for osteoporosis.
• Mycophenolate used to suppress the immune system.
• Levothyroxine for thyroid problems.
• Penacillamine for arthritis.
• Rosuvastatin to lower cholesterol.

TEXT FOR NON-MARKETED PACKS
J. COLLIS BROWNE’S TABLETS LEAFLET
PL 00240/0092
 
 

• Medicines to get rid of excess water (e.g. thiazides).
• Deflazacort, a corticosteroid.
• Ulipristal, used for emergency contraception.
• Mineral supplements (e.g. fluoride, iron, zinc).
Pregnant or breastfeeding
J. Collis Browne’s Tablets should not be used in pregnancy or breastfeeding unless the doctor
has told you to do so.
Driving and using Machinery
This medicine may cause drowsiness or other side effects which could affect your ability to drive
or use machinery (see section 4 for a full list of side effects). If you are affected do not drive or
operate machinery.
The medicine can affect your ability to drive as it may make you sleepy or dizzy.
• Do not drive while taking this medicine until you know how it affects you.
• It is an offence to drive if this medicine affects your ability to drive.
• However , you would not be committing an offence if:
o The medicine has been prescribed to treat a medical or dental problem and
o You have taken it according to the instructions given by the prescriber or in the
information provided with the medicine and
o It was not affectiong your ability to drive safely
Talk to your doctor or pharmacist if you are not sure whether it is safe for you to drive while
taking this medicine.
Important information about some of the ingredients
This medicine contains sucrose. If you have been told by your doctor that you have an
intolerance to some sugars, contact your doctor before taking this medicine.
3. How to use this medicine
Take this medicine by mouth.
Adults and children over 12 years
• Take two or three tablets every 4 hours, but not more than 6 doses in 24 hours.
Children under 12 years
• Do not give to children 12 years unless your doctor tells you to.

TEXT FOR NON-MARKETED PACKS
J. COLLIS BROWNE’S TABLETS LEAFLET
PL 00240/0092
 
 

DO NOT EXCEED THE STATED DOSE.
As well as taking these tablets you must also make sure that you replace fluids lost during
diarrhoea.
If your symptoms persist for longer than 2 days you should ask your doctor for advice.
If you take too many
If you accidentally take too many tablets, see a doctor straight away. Take the pack with you to
show which medicine you have swallowed.
If you forget a dose
Take the next dose as soon as you remember. Do not take a double dose. You can then carry on
with the normal dose at the correct time.
4. Possible side effects
Like all medicines J.Collis Browne’s Tablets can have side effects, although these don’t affect
everyone.
Possible side effects are:
• Allergic reactions (rash, itching, wheezing).
• Feeling sick.
• Being sick.
• Constipation, stomach cramps or wind.
• Drowsiness.
• Sleep disturbances.
• Confusion, dizziness or fainting.
• Difficulty in passing urine or reduced amounts of urine when you do urinate.
• Spasms.
• Dry mouth.
• Sweating.
• Headache.
• A flushed face.
• Vertigo.
• Changes in heart rate.
• High blood pressure.
• Fluid retention.
• Palpitations (awareness of your heartbeat).
• Low blood pressure or body temperature.
• Hallucinations (seeing or hearing things).
• Restlessness or mood changes.
• Addiction.

TEXT FOR NON-MARKETED PACKS
J. COLLIS BROWNE’S TABLETS LEAFLET
PL 00240/0092
 
 

• Pinpoint pupils.
• Visual disturbances.
• Absence of periods.
• Loss of sex drive.
If you notice these or any other side effect not included above, stop use and tell your doctor or
pharmacist. They will tell you what to do.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible
side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card
Scheme at: www.mhra.gov.uk/yellowcard
By reporting side effects you can help provide more information on the safety of this medicine.
5. Storing this medicine
• Keep it out of the sight and reach of children.
• There are no special storage conditions for storing this medicine.
• Do not use after the expiry date shown on the carton. The expiry date refers to the last day of
that month.
• Medicine should not be disposed of via wastewater or household waste. Ask your pharmacist
how to dispose of any unused medicine. These measures will help to protect the environment.
6. Further information
What is in this medicine
The active ingredients per tablet are:
morphine hydrochloride 0.35mg, light kaolin 750mg, calcium carbonate 200mg.
The other ingredients are:
magnesium stearate, sodium polymetaphosphate, sucrose, talc, pink dye (E127), liquorice
powder, peppermint flavour.
What the medicine looks like
J.Collis Browne’s Tablets are flat mottled pink tablets with ‘J.Collis Browne’ embossed on one
face. They are available in blister packs of 18 or 36 tablets.
Marketing authorisation holder and manufacturer
Thornton & Ross Ltd., Huddersfield, HD7 5QH, UK.
This leaflet was last revised in November 2014
J.Collis Browne’s is a trade mark of Thornton & Ross Ltd.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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