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Active substance: PEPPERMINT OIL

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J. Collis Browne’s
(morphine, peppermint oil)


Important information about J. Collis Browne’s
• This medicine relieves the symptoms of
coughs and diarrhoea in adults, the elderly
and children over 6 years.
Do not take….
• If you have breathing problems.
• Or give to children under 6 years.
• Avoid drinking alcohol while taking this
medicine. See section 2.
• Different doses are needed depending on
whether you take this medicine for a cough or
for diarrhoea. See section 3.
Now read the rest of the leaflet before you
use this medicine. It includes other
information which might be especially
important for you.
• Keep this leaflet. You may need to read it
• Ask your pharmacist if you need any more
information or advice.
• If you notice any side effects not listed in this
leaflet please tell your doctor or pharmacist.

1. What the medicine is for
J. Collis Browne’s Mixture relieves coughs and
the symptoms of diarrhoea. The medicine
contains morphine which helps calm and reduce
the effects of diarrhoea and griping pains. It also
contains peppermint oil which calms the
stomach and relieves flatulence and griping.

3. How to use this medicine
Take this medicine by mouth.

For Diarrhoea
Adults, the elderly and children over 12
• Take two or three 5ml spoonfuls (10-15ml)
every 4 hours up to a maximum of three


Children aged 6-12 years
• Give one 5ml spoonful every 4 hours up to a
maximum of three doses.

For coughs
Adults, the elderly and children over 12
• Take one or two 5ml spoonfuls (5-10ml) every
4 hours.

Children aged 6-12 years
• Give one 5ml spoonful every 4 hours.

Children under 6 years
Do not give to children under 6 unless your
doctor tells you to.
If your symptoms persist you should ask your
doctor for advice.

If you take too much
If you accidentally take too much, see a doctor
straight away. Take the pack with you to show
which medicine you have swallowed.

2. Before you use this
Do not use the medicine if you or
your child have….
• An allergy to any of the ingredients listed in
section 6.
• Shallow breath or breathing difficulties.
• A head injury or persistent headache.
• An asthma attack.
• Taken MAOIs (monoamine oxidase
inhibitors) for depression within the last two
• A blocked intestine or inflammation of your
colon or rectum.
• An addiction to alcohol.
• Or your child is under 6 years old.

Talk to your doctor if you or your
child have….
• Kidney or liver problems.
• Low blood pressure.
• Prostate problems.
• An under active thyroid gland.
• Epilepsy or fits.
• An addiction to drugs such as painkillers or
• Or are elderly, or weak as you may react
differently to this medicine.

Talk to your doctor or pharmacist if
you or your child are taking….
• Any tranquillisers/sedatives (e.g. diazepam,
• Any antidepressants (e.g. MAOIs, SSRIs
• Any sleeping tablets (e.g. temazepam,

• Any medicine for mental illness (e.g.
chlorpromazine, haloperidol).
• Any medicine to treat epilepsy (e.g.
carbamazepine, phenytoin).
• Any medicine for a heart problem (e.g.
• Medicines to thin the blood (e.g. warfarin).
• Alcohol.
• Cimetidine for a stomach ulcer.
• Metoclopramide or domperidone for nausea
and vomiting.
• Cisapride for gastric reflux.

Pregnant or breastfeeding….
Ask your doctor or pharmacist for advice before
using this medicine if you are pregnant, might
be pregnant or are breastfeeding.

Important information about some
of the ingredients
This medicine contains 2.3 vol% ethanol
(alcohol), i.e. up to 351mg per 15ml dose,
equivalent to 7ml beer or 3ml wine per dose.
Harmful for those suffering from alcoholism.
To be taken into account in pregnant and
breastfeeding women, children and high risk
groups such as patients with liver disease and
It also contains sorbitol, sucrose and fructose.
If you have been told by your doctor that you
have an intolerance to some sugars, contact
your doctor before taking this medicine.

Turn over

If you forget a dose
Take the next dose as soon as you remember.
Do not take a double dose. You can then carry
on with the normal dose at the correct time.

4. Possible side effects
Like all medicines J. Collis Browne’s Mixture
can have side effects, although these don’t
affect everyone.
Possible side effects are:
• Allergic reactions (rash, itching, wheezing).
• Feeling sick.
• Being sick.
• Constipation.
• Drowsiness.
• Difficulty in passing urine or reduced amounts
of urine when you do urinate.
• Spasms.
• Dry mouth.
• Sweating.
• Headache.
• A flushed face.
• Vertigo.
• Changes in heart rate.
• Palpitations (awareness of your heartbeat).
• Low blood pressure or body temperature.
• Hallucinations (seeing or hearing things).
• Restlessness or mood changes.
• Addiction.
• Pinpoint pupils.
• Loss of sex drive.
If you notice these or any other side effect not
included above, stop use and tell your doctor or
pharmacist. They will tell you what to do.

5. Storing this medicine
• Keep it out of the reach and sight of children.
• There are no special storage conditions for
storing this medicine.
• Do not use after the expiry date shown on the
carton. The expiry date refers to the last day
of that month.
• Medicine should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of any unused
medicine. These measures will help to protect
the environment.

6. Further information
What is in this medicine
The active ingredients per 5ml are:
morphine hydrochloride equivalent to 1.0mg
anhydrous morphine, peppermint oil 1.5
The other ingredients are:
ethanol (alcohol), benzoic acid (E210),
capsicum tincture, caramel (E150), chloroform,
citric acid (E330), hypromellose, sorbitol
solution, treacle (containing sucrose and
fructose), purified water.

What the medicine looks like
J. Collis Browne’s Mixture is a dark brown
liquid which smells of peppermint and caramel.
It is supplied in bottles of 45ml and 100ml.

Marketing authorisation holder and
Thornton and Ross Ltd., Huddersfield,
HD7 5QH, UK.
This leaflet was revised in November 2008
J. Collis Browne’s is a trade mark of Thornton
& Ross Ltd.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.