ISOSORBIDE MONONITRATE TABLETS 10MG

Active substance: ISOSORBIDE MONONITRATE DILUTED IN LACTOSE

View full screen / Print PDF » Download PDF ⇩

Transcript
Isosorbide Mononitrate
10mg, 20mg and 40mg tablets
Read all of this leaflet carefully before you
start taking this medicine.
K
•  eep this leaflet. You may need to read it
again.
•  f you have any further questions, ask your
I
doctor or pharmacist.
T
•  his medicine has been prescribed for you.
Do not pass it on to others. It may harm
them, even if their symptoms are the same
as yours.
I
•  f you have any of the side effects, or if you
notice any not listed, please tell your doctor
or pharmacist.

In this leaflet:
1 What Isosorbide Mononitrate tablets
are and what they are used for
2 Before you take Isosorbide
Mononitrate tablets
3 How to take Isosorbide Mononitrate
tablets
4 Possible side effects
5 How to store Isosorbide Mononitrate
tablets
6 Further information

1 What Isosorbide Mononitrate tablets
are and what they are used for

Isosorbide Mononitrate belongs to a group of
medicines called nitrate vasodilators. These
work by relaxing the blood vessels of the heart,
reducing the strain on the heart making it easier to
pump blood.
Isosorbide Mononitrate tablets may be used to:
•  elieve the pain and frequency of angina attacks.
r
h
•  elp control certain types of heart failure.

2 Before you take Isosorbide
Mononitrate tablets

Do not take Isosorbide Mononitrate tablets
if you:

•  re allergic (hypersensitive) to isosorbide
a
mononitrate, isosorbide dinitrate or any of the
ingredients in the tablet (see section 6). An
allergic reaction may include a rash, itching or
difficulty breathing
Continued top of next column
AAAD5186 50653501

•  ave any condition where your blood pressure
h
is very low or your blood is not circulating
properly (such as shock)
•  ave angina that is caused by an enlarged heart
h
muscle
•  ave suffered from a head injury or bleeding in
h
the brain
•  ave severe anaemia.
h

Check with your doctor or pharmacist
before taking Isosorbide Mononitrate
tablets if you:

•  ave glaucoma (increased pressure in the eye)
h
h
•  ave severe kidney or liver problems
h
•  ave an underactive thyroid gland
a
•  re undernourished as a result of a poor diet
•  re suffering from hypothermia
a
h
•  ave an undiagnosed pituitary tumour (brain
tumour).

Taking other medicines

Please tell your doctor or pharmacist if you
are taking or have recently taken any other
medicines, including medicines obtained without
a prescription. Especially:
n
•  oradrenaline (norepinephrine) – to treat high
blood pressure or heart attack
•  cetylcholine – used in some operations
a
•  edicines to treat high blood pressure such as
m
ACE inhibitors, beta blockers, alphablockers,
angiotensin-II receptor agonists, clonidine,
diazoxide, diuretics (water tablets), methyldopa,
moxonidine,
•  istamine – to treat allergic reactions
h
•  ildenafil , tadalafil and vardenafil, used to
s
treat male erection dysfunction, should not
be taken if taking nitrate preparations such
as Isosorbide Mononitrate tablets because a
severe and possibly dangerous fall in blood
pressure can occur. This would result in collapse,
unconsciousness and could be fatal.

Pregnancy and breastfeeding

If you are pregnant, planning to become pregnant
or breastfeeding speak to a doctor before taking
Isosorbide Mononitrate tablets.

Driving and using machines

Isosorbide mononitrate may make you feel dizzy,
make sure you are not affected before you drive or
operate machinary.
Continued over page

Sugar intolerance

If you have been told that you have an intolerance
to some sugars, contact your doctor before taking
this medicine, as it contains lactose.

Taking Isosorbide Mononitrate tablets
with alcohol

You are advised not to drink alcohol with this
medicine as it may increase the blood pressure
lowering affect of the tablets.
If you see another doctor or go into hospital, let
them know what medicines you are taking.

3 How to take Isosorbide Mononitrate
tablets

Always take Isosorbide Mononitrate tablets exactly
as your doctor has told you. If you are not sure,
check with your doctor or pharmacist.
Swallow the tablets with water after meals.
The usual doses are:
•  dults
A
A
-  ngina: initially 20mg two or three times a
day, then a maintenance dose of between 20120mg a day.
-  ongestive heart failure: 20mg two or three
C
times a day depending on your condition. Your
doctor may also be treating you with other
drugs.
•  atients with kidney or liver disease – a lower
P
dose may be given.
•  lderly: Dose should be reduced especially in
E
patients with kidney or liver disease.
•  hildren: Not recommended
C

If you take more Isosorbide Mononitrate
tablets than you should

If you (or someone else) swallow’s a lot of
tablets at the same time, or you think a child
may have swallowed any contact your nearest
hospital casualty department or tell your doctor
immediately. Signs of an overdose over excited,
flushing, feeling or being sick, cold sweats, feeling
dizzy or spinning sensation, fainting or passing
out, fast heart beat or fall in blood pressure.

If you forget to take Isosorbide
Mononitrate tablets

Do not take a double dose to make up for a
forgotten dose. If you forget to take a dose take it
as soon as you remember it and then take the next
dose at the right time.

If you stop taking the tablets

Do not stop taking the tablets without talking to
your doctor and follow their advice.

4 Possible side effects

Like all medicines, Isosorbide Mononitrate tablets
can cause side effects, although not everybody
gets them. Please tell your doctor or pharmacist if
you notice any of the following effects or any not
listed.
Contact your doctor at once if you experience
symptoms of an allergic reaction skin rash,
swelling of the skin of the extremities or
face, swelling of lips, tongue, or the mucous
membranes in mouth, throat, or airways, resulting
in shortness of breath or difficulty to swallow.
Tell your doctor if you notice any of the
following side effects or notice any other effects
not listed:
•  eadaches, which can be relieved with
h
painkillers and usually get better after 1-3 weeks
of treatment.
•  ry or flaky skin rash
d
•  eing sick, heartburn
b
•  laucoma (pressure within the eye)
g
f
•  lushing, dizziness, weakness, fainting on
standing, fast or slow heart rate, temporary low
levels of oxygen in the blood.

5 How to store Isosorbide Mononitrate
tablets

Keep out of the reach and sight of children.
Store below 25°C in a dry place.
Do not use Isosorbide Mononitrate tablets after
the expiry date stated on the label/carton/bottle.
The expiry date refers to the last day of that
month.
Medicines should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of medicines no longer
required. These measures will help to protect the
environment.

6 Further information

What Isosorbide Mononitrate tablets
contain

•  he active substance (the ingredient that makes
T
the tablets work) is isosorbide mononitrate. Each
tablet contains either 10mg, 20mg or 40mg of
the active ingredient.
T
•  he other ingredients are crospovidone, lactose,
magnesium stearate, maize starch, povidone and
E460 (10mg and 40mg only).

What Isosorbide Mononitrate tablets look
like and contents of the pack
Isosorbide Mononitrate tablets are circular,
biconvex, white to off white uncoated tablets.
Pack sizes are 56 tablets
Marketing Authorisation holder and
manufacturer
Actavis, Barnstaple, EX32 8NS, UK
Date of last revision: June 2012

Continued top of next column
AAAD5186 50653501



Actavis, Barnstaple, EX32 8NS, UK



Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Hide
(web3)