CORACTEN SR CAPSULES 10MG

Active substance: NIFEDIPINE

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CORACTEN SR CAPSULES 10 mg and CORACTEN SR CAPSULES 20 mg
Nifedipine PATIENT INFORMATION LEAFLET

Medicines like Coracten SR Capsules have been
shown in laboratory experiments to impair
sperm function. If you are male and have been
unsuccessful in fathering a child please consult
your doctor.
Taking Coracten SR with food or drink
Coracten SR may be taken with or without food.
As a safety precaution, do not take with alcohol.

Coracten SR is an antihypertensive or anti-anginal
medicine and belongs to a group of medicines
called calcium-channel blockers.

FRONT

1. What Coracten SR is and
what it is used for

Driving and using machines
Coracten SR may cause dizziness and tiredness.
A large drop in blood pressure may result in
temporary loss of vision. If affected by any of
these you should not drive or use machines.

Used to treat:
To prevent:
chronic stable angina pectoris (heart/chest
pain).
PLEASE NOTE: These capsules are sustainedrelease capsules which release the active
ingredient slowly over 12 hours. Do not use to
treat attacks of angina or heart attacks when
they happen. See your doctor if you are unsure
why you have been prescribed these capsules.

2. Before you take Coracten SR
Do not take this medicine if you have/are:
Allergic to any of the ingredients in
Coracten SR or other dihydropyridines such
as amlodipine, felodipine, isradipine or
nisolidipine.
Taken nifedipine before and found your heart
pain got worse
Pregnant, or likely to become pregnant and
breast- feeding
Porphyria
Narrowing (stenosis) of the aortic valve (one of
the valves of the heart)
Unstable angina (heart pain)
Suffered a heart attack less than one month
ago
Collapse of the circulation (cardiogenic shock)
Very high blood pressure (malignant
hypertension)
Taking rifampicin – a treatment for
tuburculosis
If you have a “Kock pouch” (a surgically
constructed intestinal reservoir with an
opening through the abdominal wall) in your
gut.
This medicine is not recommended for use in
children
Do not drink grapefruit juice while you are on
Coracten SR, as the absorption of the drug is
increased and this will make your blood pressure
drop too low and your heart beat faster.

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>> READ DIRECTION
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Tell your doctor if the answer is yes to any of the
following statements, as special care should then
be taken.
Do you have:
Heart problems other than chronic stable
angina (heart failure)
Low or high blood pressure
Diabetes
Kidney failure and require dialysis
Liver disease
Are you taking any other medicines?
Tell your doctor if you are taking any other
medicine, especially:
Beta-blockers for high blood pressure (If you
are changing from beta-blockers to Coracten
SR, you should gradually reduce your betablockers over 10 days, after discussion with
your doctor).
Other calcium channel blockers such as
diltiazem
Medicines to treat infections such as the
antibiotics: erythromycin, dalfopristin and
quinupristin, ritanovir (for HIV) and antifungal
medicines
Anti-epilepsy drugs such as valproic
acid, carbamazapine, phenytoin and
phenobarbitone
Medicines used during an operation such
as anaesthetics and the muscle relaxants
tubocurarine or vecuronium
Anti-depressants such as fluoxetine and
nefazodone
Antipsychotic medicines (used to treat mental
illness) such as chlorpromazine, fluphenazine
Intravenous ionic X-ray contrast mediums (used
to help show internal organs more clearly)
Medicines to treat various heart conditions
such as digoxin, quinidine, prazosin, diuretics
(water tablets)

This medicine contains lactose
If you have been told by your doctor that you
have an intolerance to some sugars, contact your
doctor before taking this medicinal product.

3. How to take Coracten SR
Coracten SR should be swallowed whole with
a drink of water. Do not break or chew the
capsules. The usual dose is one 10 mg or one 20
mg capsule (every 12 hours). Doses of up to 80
mg per day may be prescribed by your doctor if
considered necessary.
Please read the pharmacist’s label for further
instructions on how many to take and when to
take the capsules. If the dosage is not clear to
you, check with your doctor or pharmacist.
How long should I take them for?
Treatment for high blood pressure or angina is
usually for life. Your doctor will monitor your
treatment and check your blood pressure. Do not
stop taking the capsules unless your doctor tells
you to. DO NOT EXCEED THE STATED DOSE
What if I take too many?
If you take too many go straight to your casualty
department. Take the capsules, box and this
leaflet with you.
What if I forget a dose?
Do not worry. Take the missed dose as soon as
you remember and take the next dose 24 hours
later. Do not take more than your prescribed dose
in 24 hours. If you do not remember your missed
dose until it is time for your next one then do
not take the missed dose. Tell your doctor at your
next visit if you have missed a few doses.

4. Possible side-effects
Like all medicines Coracten can cause side effects
although not everyone gets them.
It is important that you are aware of what these
side effects may be. They are usually mild and
disappear after a short time.
Stop taking Coracten and seek urgent medical
help immediately if you suffer from:
An increase in chest pain at the start of
treatment
An allergic reaction and experience difficulty
breathing, with or without swelling of the
face, lips, tongue, and/or throat which may
cause difficulty in swallowing.
Also stop taking Coracten and talk to your doctor
immediately if you:
Start shaking or experience a loss of eyesight
caused by a sudden drop in blood pressure
Notice a yellowing of the skin and eyes caused
by liver problems such as allergic hepatitis,
intra-hepatic cholestasis
Notice flaking or purple blotching of the skin
caused by exfoliative dermatitis, erythema
multiform or pemphigoid reactions.
Other side-effects
If any of the following side-effects become
troublesome, continue taking Coracten but talk
to your doctor immediately:
Common side effects - These may affect up to 1
in 10 people:
headache, general feeling of being unwell,
constipation, swelling, particularly of the ankles
and legs.
Uncommon side effects - These may affect up to
1 in 100 people:
stomach pain, unspecific pain, low blood
pressure when standing up (symptoms include
fainting, dizziness, light headedness, occasional
palpitations, blurred vision and sometimes
confusion), fainting, faster or irregular heartbeat
(palpitations), dry mouth, indigestion or upset
stomach, wind (flatulence), feeling sick (nausea),
muscle cramps, joint swelling, sleep disorders,

>> READ DIRECTION

If you are unsure about your other medication,
please talk to you doctor or pharmacist before
taking Coracten SR. They may need to alter your
treatment or give you some special advice.

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In this leaflet:
1. What Coracten SR is and what it is used for
2. Before you take Coracten SR
3. How to take Coracten SR
4. Possible side effects
5. How to store Coracten SR
6. Further information

Magnesium sulphate as injection
Aldesleukin to treat cancer of the kidneys
Alprostadil for erectile dysfunction
Medicines used following organ or tissue
transplants such as ciclosporin and tacrolimus
Cisapride to treat disorders of the stomach and
digestion
Cimetidine to treat stomach/gastric ulcers
Mizolastin to treat hayfever, theophylline to
treat asthma
Herbal medicines such as St John’s Wort,
gingko biloba, ginseng.
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Read all this leaflet carefully before you start
taking this medicine.
- Keep this leaflet. You may need to read it
again.
- If you have any further questions, ask your
doctor or pharmacist.
- This medicine has been prescribed for you.
Do not pass it on to others.
- If any of the side effects get serious, or
if you notice any side effects not listed
in this leaflet, please tell your doctor or
pharmacist.

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anxiety or nervousness, reddening of the skin,
nosebleeds, nasal congestion, a feeling of
dizziness or “spinning” (vertigo), migraine,
trembling, increase in the need to pass water
(urinate), painful or difficult urination, inability
to achieve an erection (impotence), blurred
vision, temporary increase in certain liver
enzymes.
Rare side effects - These may affect up to 1 in
1,000 people:
pins and needles, itchy skin, rash, hives, changes
in mood, inflammation or the gums, tender or
swollen gums, bleeding gums.
Other side effects - Frequency unknown:
a reduction in the number of white blood cells
(leucopenia), a more severe decrease in the
number of white blood cells (agranulocytosis),
depression, increased blood sugar
(hyperglycaemia), decreased skin sensitivity
(hypoaesthesia), sleepiness, lethargy, insufficient
blood flow to the brain, eye pain, chest pain
(angina pectoris), decreased blood flow to
your heart, flushing, vomiting, heartburn
or indigestion (gastroesophageal sphincter
insufficiency), diarrhoea, sensitivity to light
(photosensitivity allergic reaction), small raised
areas of bleeding in the skin (palpable purpura),
spider veins, joint pain, muscle pain, muscle
weakness, fever, worsening of myasthenia gravis.
The development of breast tissue in older men on
long term therapy has been reported.
Because of the nature of coronary heart disease,
heart attacks have occurred in patients treated
with the active ingredient, nifedipine. It has not
been shown that these heart attacks were due to
treatment with nifedipine.
Reporting of side effects
If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible
side effects not listed in this leaflet. You can also
report side effects directly via the Yellow Card
Scheme at: www.mhra.gov.uk/yellowcard
By reporting side effects you can help provide
more information on the safety of this medicine.

5. How to store Coracten SR
Do not use after the expiry date shown on the
pack and the blister foil. Keep the capsules in
their original package.
Do not store above 25°C.
KEEP THIS AND ALL MEDICINES OUT OF THE
SIGHT AND REACH OF CHILDREN.
Return all unused medicines to a pharmacy for
disposal.

6. Further Information
Coracten SR is available in 10 mg and 20 mg
capsules and comes in packs of 60 capsules
containing 10 mg or 20 mg of the active
ingredient nifedipine.
The 10 mg capsules have a grey body with a
brownish- pink cap overprinted in white with
Coracten 10 mg. The 20 mg capsules have a
brownish-pink body with a reddish brown cap
overprinted in white with Coracten 20 mg.
Other ingredients include: sucrose, maize
starch, lactose, povidone K30, methacrylic acid
copolymer type A (Eudragit L100), talc, purified
water.
Capsule shells: gelatin, red iron oxide (E172),
yellow iron oxide (E172), titanium dioxide (E171),
black iron oxide (E172, 10 mg only).
Printing ink: titanium dioxide, shellac, propylene
glycol, sodium hydroxide, povidone.
This leaflet does not contain all the information
about your medicine. If you have any questions
or are not sure about anything, ask your doctor
or pharmacist, who will have access to further
information.
High blood pressure and heart disease are very
common. It is important to help yourself by
losing weight if you need to and taking regular
exercise. Your doctor can put you in touch
with organisations that offer information and
advice to people in your situation. One such
organisation is The British Heart Foundation.
Marketing Authorisation Holder and
Manufacturer MA Holder: UCB Pharma Ltd, 208
Bath Road, Slough, Berkshire, SL1 3WE.

2014-190314

Date of preparation of the leaflet: May 2014.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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