COLESTID ORANGE 5G

Active substance: COLESTIPOL HYDROCHLORIDE

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Package leaflet: Information for the patient

OLESTID

®

Colestid ® Orange 5.0g
Colestipol hydrochloride

Spine
Colestid®
Orange

FPO – 128

NO COPY

Read all of this leaflet carefully before you start taking this
medicine because it contains important information for
you.
– Keep this leaflet. You may need to read it again.
– If you have any further questions, ask your doctor or
pharmacist.
– This medicine has been prescribed for you only. Do not pass
it on to others. It may harm them, even if their signs of illness
are the same as yours.
– If you get any side effects, talk to your doctor or pharmacist.
This includes any possible side effects not listed in this
leaflet. See section 4.
What is in this leaflet:
1. What Colestid Orange is and what it is used for
2. What you need to know before you take Colestid Orange
3. How to take Colestid Orange
4. Possible side effects
5. How to store Colestid Orange
6. Contents of the pack and other information

you are using. The “grittiness” of Colestid Orange is much more
obvious in “dilute” drinks such as water or fruit juice. Some
people mix up Colestid Orange the night before to improve
results.
If you take more Colestid Orange than you should
Never take more Colestid Orange than your doctor has told you.
If you do, tell your doctor because you may get constipation.
If you forget to take Colestid Orange
Don’t worry. Take your next sachet (or sachets) at the usual
time.
Do not take a double dose to make up for a forgotten dose.
If you stop taking Colestid Orange
Do not stop taking your medicine or alter the dose you are
currently taking without seeing your doctor first.
If you have any further questions on the use of this medicine,
ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, this medicine can cause side-effects,
although not everyone gets them.
Tell your doctor immediately if you experience any of the
following symptoms after taking this medicine:
- constipation, which is usually mild and does not last for
long. Eating more fibre and drinking plenty of fluid usually
helps. Sometimes it can be more severe which may cause a
blockage in your colon. If this happens you might need some
treatment like an enema, to relieve the blockage. Constipation
can make piles (haemorrhoids) worse and you may notice
blood in your stools.
- stomach ulcers and bleeding stomach ulcers. These will
cause severe stomach pains and if these start to bleed you
may pass very dark stools or bring up blood if you are sick.
- inflammation of the gall bladder, gallstones or yellowish skin.
- chest pain, angina-like feelings or you may feel your heart
beat speeding up.
- allergy effects like a rash, itchy skin or hives.
- aches and pains in your joints and muscles, especially your
fingers and toes. You may also feel backache.
- headaches, some of which may feel quite severe (migraine,
sinus headache) or feel dizzy and light-headed. You may also
have difficulty sleeping.
- not feel like eating, feeling tired and weak, have a shortness
of breath, or swelling of your hands and feet.
Tell your doctor if you experience any of the following side
effects and they do not go away:
– stomach discomfort
– belching
– wind
– nausea (feeling sick)
– sickness or diarrhoea.
Colestid Orange affects the way that your body absorbs fats and
some ‘fat-soluble’ vitamins (A,D,E and K). Your doctor may give
you a vitamin supplement if they think this could be happening.
The levels of some fats and enzymes in your blood may rise.
This is usually temporary.
If you get any side effects, talk to your doctor or pharmacist.
This includes any possible side effects not listed in this leaflet.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or
nurse. This includes any possible side effects not listed in this
leaflet. You can also report side effects directly via the Yellow
Card Scheme at: www.mhra.gov.uk/yellowcard. By reporting
side effects you can help provide more information on the safety
of this medicine.

1. WHAT COLESTID ORANGE IS AND WHAT IT IS USED
FOR
Colestid Orange is a ‘lipid lowering agent’. This medicine
contains colestipol hydrochloride which is one of a group of
medicines called bile acid sequestrants.
Colestid Orange is used to help lower the level of cholesterol
in your blood. It works in the intestines, where it binds to bile
acids. Bile is a fluid that is produced by the liver. It is released
into the intestine through the bile duct as part of digestion. Bile
contains substances called bile acids, which the liver makes
from cholesterol in the blood. Bile acids aid the digestion of
fats consumed in the diet. Following digestion, the bile acids
are reabsorbed into the bloodstream and are then returned
to the liver. Colestipol binds to the bile acids in the intestine
and prevents them being reabsorbed into the bloodstream.
Instead, they pass through the intestine with the colestipol and
are excreted in the faeces. This triggers the liver to produce
more bile acids from the cholesterol in the blood, which lowers
the level of cholesterol in the blood. Your doctor will have
recommended a special diet to you in order to help you lose
weight since this is very important in lowering your cholesterol
levels. Your doctor has given you Colestid Orange since the diet
on its own is not lowering your cholesterol enough. It is still very
important that you follow your special diet even when taking
Colestid Orange. You can find out more about cholesterol from
The British Heart Foundation whose address is given at the end
of this leaflet.
You must talk to a doctor if you do not feel better or if you feel
worse.
2. WHAT YOU NEED TO KNOW BEFORE YOU TAKE
COLESTID ORANGE
Do not take Colestid Orange:
– if you are allergic (hypersensitive) to colestipol hydrochloride
or any of the other ingredients of Colestid Orange (listed in
section 6).
Warnings and precautions
Talk to your doctor or pharmacist before using Colestid Orange
if you have:
• an under-active thyroid gland
• nephrotic syndrome (a kidney problem where you get protein
in your urine and too much fluid collecting in your body)
• too much or too little protein in your blood
• liver problems e.g. jaundice
• diabetes
• phenylketonuria e.g. you are on a special diet that is low in
phenylalanine
Use in children and adolescents
Colestid Orange will not normally be given to children. Ask your
doctor for more information if they have prescribed Colestid
Orange for a child in your care. If children or young adults are
given this medicine, your doctor will need to check their growth
and development regularly.
Other medicines and Colestid Orange
Tell your doctor or pharmacist if you are taking, have recently
taken or might take any other medicines, including medicines
taken without a prescription.
There are some medicines that may interact with Colestid
Orange and it can affect the way they work.
It is especially important to tell your doctor if you are taking the
following medicines:
• heart drugs e.g. digoxin, digitoxin
• beta-blockers e.g. propranolol - for high blood pressure,
angina, migraine or anxiety symptoms
• water tablets (‘diuretics’) e.g. chlorothiazide or furosemide usually for heart or kidney problems
• antibiotics e.g. tetracycline hydrochloride and penicillin G
• another cholesterol-lowering medicine called gemfibrozil
Your doctor may need to change your dose of these medicines.
If you are taking propranolol, your doctor will need to check your
dose when you start taking Colestid Orange and also when you
stop.
Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be
pregnant or are planning to have a baby, ask your doctor or
pharmacist for advice before taking this medicine. Your doctor
may stop your treatment.

5. HOW TO STORE COLESTID ORANGE
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on
the carton and sachet after EXP. The expiry date refers to the
last day of the month.
Do not store above 30°C.
Do not throw away any medicines via wastewater or household
waste. Ask your pharmacist how to throw away medicines
you no longer use. These measures will help to protect the
environment.
6. CONTENTS OF THE PACK AND OTHER INFORMATION
What Colestid Orange contains
– The active substance is colestipol hydrochloride. Each 7.5 g
sachet contains 5 g of colestipol hydrochloride.
– The other ingredients are
  Mannitol E421
   Methylcellulose (15CPS) E461
   Citric Acid E330
  Orange Durarome Wonf
   Aspartame Powder E951
  Maltol
  Ethyl Vanillin
   Beta Carotene 1% E160a
  Glycerol E422
  Purified Water
What Colestid Orange looks like and contents of the pack
– Colestid Orange is yellow granules for oral suspension with
orange particles.
– Colestid Orange comes in a carton of 30 sachets.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Pharmacia Limited
Ramsgate Road
Sandwich
Kent
CT13 9NJ
Manufacturer
Pfizer Service Company BVBA,
10 Hoge Wei,
1930 Zaventem,
Belgium.
Company Contact Address
For further information on this medicine, please contact Medical
Information at Pfizer Limited, Walton Oaks, Tadworth, Surrey,
Tel: +44 1304 616161
More information about cholesterol
If you would like any more information about changing your
lifestyle to lower your cholesterol you can contact:
The British Heart Foundation, 14 Fitzhardinge Street, London,
W1H 4DH
Tel. 020 7935 0185
This leaflet was last revised in 10/2013

Driving and using machines
Your ability to drive or operate machines is not affected by
taking Colestid Orange.
Colestid Orange contains aspartame
Colestid Orange contains 32.5 mg aspartame which contains
(18.2 mg phenylalanine) per sachet. This needs to be taken
into consideration in people suffering from a condition known
as phenylketonuria, since excessive amounts of aspartame
may interfere with the control of this condition. If you suffer from
phenylketonuria you should discuss this with your doctor before
taking Colestid Orange.
3. HOW TO TAKE COLESTID ORANGE
Always take this medicine exactly as your doctor or pharmacist
has told you. Check with your doctor or pharmacist if you are
not sure.
Colestid Orange must not be taken as a dry powder and must
be mixed with a drink or taken with liquid food. The Colestid
Orange powder should be mixed thoroughly with at least 100 ml
of water or another still drink such as orange or skimmed milk.
Alternatively, Colestid Orange can be taken with soup or cereal
or with pulpy fruit such as grapefruit, provided that there is at
least 100 ml or more of liquid.

Ref: CL 6_4
13769801

Colestid Orange has an orange/vanilla smell. It is flavoured with
orange and vanilla and contains artificial sweeteners.
Your doctor will advise you on the amount of Colestid Orange
you should take, and when.
Most people start by taking one to two sachets of Colestid
Orange per day. Your doctor may increase your dose each
month until your cholesterol reaches the best level for you. Do
not change the number of sachets you take unless your doctor
tells you to. Do not take more than 6 sachets (30 grams) a day.
If you are prescribed more than two sachets per day, it may
be preferable to take Colestid Orange as two separate doses,
leaving several hours between e.g. with breakfast and an
evening meal.
Taking Colestid with other medicines
If you have other medicines to take, make sure you take them at
least one hour before or four hours after your Colestid Orange
except if you are taking gemfibrozil, take this at least two hours
before or after your Colestid Orange.
You may have to take Colestid Orange every day for a long time.
It is important that you stick to your recommended diet as well
as taking your Colestid Orange.
Colestid Orange does not actually dissolve and it therefore has
a “gritty” texture, especially if it is not well mixed with the liquid

Time/Date:

13769801.indd 1

12/4/13 10:36 AM



Project No.

Artwork Number

Description



11204

13769801

Colestid Orange



Dimensions

GA

D Huff

SKU No.

Item

DWG-102579-00

1723

Insert

Colors:

Minimum Text’s Font Size: 9 pts
Not condensed
Mgr M Wolpert
GS C Connelly

UK

Drawing No.

29.50” x 4.0” (4.0” x 1.0” folded)
rev. 08JUN11
Additional Info:

Country

EDITOR’S COPY
Black

Rev

11

GA

Yellow

Magenta

Cyan

PMS 1375

PR

GS: DATE:

Dieline

GS / ART REV (LCA)

GS / ART REV (FA)

CHANGES

CHANGES

CHANGES

OK

OK

OK

18/171

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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