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What you need to know before you
take Colestid Granules

Package leaflet:
Information for the patient

Colestid® Granules
for Oral Suspension 5.0g
Colestipol hydrochloride

Read all of this leaflet carefully before
you start taking this medicine because it
contains important information for you.

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your
doctor or pharmacist.
• This medicine has been prescribed for you only. Do
not pass it on to others. It may harm them, even if
their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor
or pharmacist. This includes any possible side
effects not listed in this leaflet. See section 4.

What is in this leaflet:

1. What Colestid Granules is and what it is used
2. What you need to know before you take
Colestid Granules
3. How to take Colestid Granules
4. Possible side effects
5. How to store Colestid Granules
6. Contents of the pack and other information

What Colestid Granules is and what
it is used for
Colestid Granules is a ‘lipid lowering agent’. This
medicine contains colestipol hydrochloride which
is one of a group of medicines called bile acid
Colestid Granules is used to help lower the level
of cholesterol in your blood. Your doctor will have
recommended a special diet to you in order to help
you lose weight since this is very important in
lowering your cholesterol levels. Your doctor has
given you Colestid Granules since the diet on its
own is not lowering your cholesterol enough. It is
still very important that you follow your special diet
even when taking Colestid Granules. You can find
out more about cholesterol from The British Heart
Foundation whose address is given at the end of
this leaflet.
You must talk to a doctor if you do not feel better or
if you feel worse.

Do not take Colestid Granules:
• if you are allergic (hypersensitive) to colestipol
hydrochloride or any of the other ingredients of
Colestid Granules (listed in section 6).
Warnings and precautions
Talk to your doctor or pharmacist before taking Colestid
Granules if you:
• an under-active thyroid gland
• nephrotic syndrome (a kidney problem where
you get protein in your urine and too much fluid
collecting in your body)
• too much or too little protein in your blood
• liver problems e.g. jaundice
• diabetes
Other medicines and Colestid Granules
Tell your doctor or pharmacist if you are taking, have
recently taken or might take any other medicines,
including medicines obtained without a prescription.
There are some medicines that may interact with
Colestid Granules and it can affect the way they
It is especially important to tell your doctor if you
are taking the following medicines:
• heart drugs e.g. digoxin, digitoxin
• beta-blockers e.g. propranolol - for high blood
pressure, angina, migraine or anxiety symptoms
• water tablets ('diuretics') e.g. chlorothiazide
or furosemide - usually for heart or kidney
• antibiotics e.g. tetracycline hydrochloride and
penicillin G
• another cholesterol-lowering medicine called

Your doctor may need to change your dose of these
medicines. If you are taking propranolol, your
doctor will need to check your dose when you start
taking Colestid Granules and also when you stop.
Pregnancy and breast-feeding and fertility
If you are pregnant,breast-feeding, think you
may be pregnant or are planning to have a baby,
ask your doctor or pharmacist for advice before
taking this medicine. Your doctor may stop your
Driving and using machines
Your ability to drive or operate machines is not
affected by taking Colestid Granules.

3. How to take Colestid Granules
Always take this medicine exactly as your doctor or
pharmacist has told you. Check with your doctor or
pharmacist if you are not sure.
Colestid Granules must not be taken as a dry
powder and must be mixed with a drink or taken
with liquid food. The Colestid Granules should
be mixed thoroughly with at least 100 ml of water
or another still drink such as orange or skimmed
milk. Alternatively, Colestid Granules can be taken
with soup or cereal or with pulpy fruit such as
grapefruit, provided that there is at least 100 ml or
more of liquid.

Do not change the number of sachets you take
unless your doctor tells you to. Do not take
more than 6 sachets (30 grams) a day. If you are
prescribed more than two sachets per day, it may
be preferable to take Colestid Granules as two
separate doses, leaving several hours between e.g.
with breakfast and an evening meal.
Taking Colestid with other medicines
If you have other medicines to take, make sure
you take them at least one hour before or four
hours after your Colestid Granules, except if you
are taking gemfibrozil, take this at least two hours
before or after your Colestid Granules.
You may have to take Colestid Granules every day
for a long time. It is important that you stick to your
recommended diet as well as taking your Colestid
Colestid Granules does not actually dissolve and
it therefore has a "gritty" texture, especially if it is
not well mixed with the liquid you are using. The
"grittiness" of Colestid Granules is much more
obvious in "dilute" drinks such as water or fruit
juice. In thicker mixtures such as muesli with milk,
you may not notice Colestid Granules at all. Some
people mix up Colestid Granules the night before
to improve results.

Your doctor will advise you on the amount of
Colestid Granules you should take, and when.
Most people start by taking one to two sachets
of Colestid Granules per day. Your doctor may
increase your dose each month until your
cholesterol reaches the best level for you.

You will Find more about COLESTID GRANULES
on the back of this leaflet

Use in children and adolescents
Colestid Granules will not normally be given to
children. Ask your doctor for more information if
they have prescribed Colestid Granules for a child
in your care. If children or young adults are given
this medicine, your doctor will need to check their
growth and development regularly.
If you take more Colestid Granules than you
Never take more Colestid Granules than your
doctor has told you. If you do, tell your doctor
because you may get constipation.
If you forget to take Colestid Granules
Don't worry. Take your next sachet (or sachets) at the
usual time.
Do not take a double dose to make up for a
forgotten dose.
If you stop taking Colestid Granules
Do not stop taking your tablets or alter the dose
you are currently taking without seeing your doctor

If you have any further questions on the use of this
medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause
side-effects, although not everyone gets them.
Tell your doctor if you experience any
of the following side effects and they do
not go away:
• constipation, which is usually mild and does not last
for long. Eating more fibre and drinking plenty of
fluid usually helps. Sometimes it can be more severe
and cause a blockage n your colon. If this happens
you might need some treatment like an enema, to
relieve the blockage. Tell your doctor if you think
you have this problem. Constipation can make piles
(haemorrhoids) worse and you may notice blood in
your stools. Tell your doctor immediately
if this happens.
• stomach discomfort
• belching
• wind
• nausea, feeling sick
• sickness or diarrhoea.

Other side effects
Rarely, people have noticed the following sideeffects, tell your doctor immediately if any of these
• stomach ulcers and bleeding stomach ulcers.
These will cause severe stomach pains and if
these start to bleed you may pass very dark
stools or bring up blood if you are sick.
• inflammation of the gall bladder, gallstones or
yellowish skin.
• chest pain, angina-like feelings or you may feel
your heart beat speeding up.
• allergy effects like a rash, itchy skin or hives.
• aches and pains in your joints and muscles,
especially your fingers and toes. You may also
feel backache.
• headaches, some of which may feel quite severe
(migraine, sinus headache) or feel dizzy
and light-headed. You may also have difficulty
•  ot feel like eating, feeling tired and weak, have a
shortness of breath, or swelling of your hands and
Colestid Granules affects the way that your body
absorbs fats and some 'fat-soluble' vitamins (A,
D,E and K). Your doctor may give you a vitamin
supplement if they think this could be happening.
The levels of some fats and enzymes in your blood
may rise. This is usually temporary.
Reporting of side effects
If you get any side effects, talk to your doctor, or
pharmacist. This includes any possible side effects
not listed in this leaflet.

You can also report side effects directly via the
Yellow Card Scheme at:
yellowcard. By reporting side effects you can help
provide more information on the safety of this

5. How to store Colestid Granules
Keep out of the sight and reach of children.
Do not use this medicine after the expiry date which is
stated on the carton and sachet after EXP. The expiry
date refers to the last day of the month.
This medicine does not require any special storage
Do not throw away any medicines via wastewater
or household waste. Ask your pharmacist how to
throw away medicines you no longer use. These
measures will help to protect the environment.

Contents of the pack and other
What Colestid Granules contains
• The active substance is colestipol hydrochloride.
Each 7.5g sachet contains 5g of colestipol
• The other ingredients are Colloidal
Anhydrous Silica.
What Colestid Granules looks like and
contents of the pack
• Colestid Granules are light yellow granules for
oral suspension.
• Colestid Granules come in cartons of 30 sachets.

Marketing Authorisation Holder and
Marketing Authorisation Holder
PFIZER Limited
Ramsgate Road
CT13 9NJ
10 rue Bouché Thomas
Zac Sud d’Orgemont
49007 Angers Cedex
Company Contact Address
For further information on this medicine,
please contact Medical Information at
Pfizer Limited, Walton Oaks, Tadworth, Surrey,
Tel: +44 1304 616161
More information about cholesterol
If you would like any more information about
changing your lifestyle to lower your cholesterol
you can contact:
The British Heart Foundation,
14 Fitzhardinge Street, London,
Tel. 020 7935 0185
This leaflet was last revised in 05/2014
Ref CL10_1

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.