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2. Before you take Colestid Granules

Patient Information Leaflet

Do not take Colestid Granules:
• if you are allergic (hypersensitive) to colestipol

hydrochloride or any of the other ingredients
of Colestid Granules (see section 6 for a list of

Take special care with Colestid Granules

Colestid® Granules
for Oral Suspension 5.0 g
Colestipol hydrochloride

Read all of this leaflet carefully before
you start taking this medicine

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your

doctor or pharmacist.
This medicine has been prescribed for you.
Do not pass it on to others. It may harm them,
even if their symptoms are the same as yours.
If any of the side effects gets serious, or if you
notice any side effects not listed in this leaflet,
please tell your doctor or pharmacist.

In this leaflet:

1. What Colestid Granules is and what
it is used for
2. Before you take Colestid Granules
3. How to take Colestid Granules
4. Possible side effects
5. How to store Colestid Granules
6. Further information

1. What Colestid Granules is
and what it is used for
Colestid Granules is a ‘lipid lowering agent’.
Colestid Granules is one of a group of medicines
called bile acid sequestrants. The active
ingredient is colestipol hydrochloride.
Colestid Granules is used to help lower the level
of cholesterol in your blood. Your doctor will have
recommended a special diet to you in order to
help you lose weight since this is very important
in lowering your cholesterol levels. Your doctor
has given you Colestid Granules since the diet
on its own is not lowering your cholesterol
enough. It is still very important that you follow
your special even when taking Colestid Granules.
You can find out more about cholesterol from
The British Heart Foundation whose address is
given at the end of this leaflet.

Tell your doctor if you have any of these problems:
• an under-active thyroid gland
• nephrotic syndrome (a kidney problem where
you get protein in your urine and too much fluid
collecting in your body)
• too much or too little protein in your blood
• liver problems e.g. jaundice
• diabetes

Taking other medicines
There are some medicines that may interact with
Colestid Granules and it can affect the way they
work. Tell your doctor about other medicines you
are taking before you start your Colestid Granules.
It is especially important to tell your doctor if you
are taking the following medicines:
• heart drugs e.g. digoxin, digitoxin
• beta-blockers e.g. propranolol - for high blood
pressure, angina, migraine or anxiety symptoms
• water tablets (‘diuretics’) e.g. chlorothiazide
or furosemide - usually for heart or kidney
• antibiotics e.g. tetracycline hydrochloride and
penicillin G
• another cholesterol-lowering medicine called

Your doctor may need to change your dose of
these medicines. If you are taking propranolol,
your doctor will need to check your dose when
you start taking Colestid Granules and also when
you stop.
Please tell your doctor or pharmacist if you
are taking or recently have taken any other
medicines, including medicines obtained without
a prescription.

Preganancy and breast-feeding

Tell your doctor if you are pregnant, or planning
to become pregnant, or if you are breastfeeding. Your doctor may stop your treatment.
Ask your doctor or pharmacist for advice before
taking any medicine.

Driving and using machines

Your ability to drive or operate machinery is not
affected by taking Colestid Granules.

3. How to take Colestid Granules

Always take your medicine exactly as your doctor
has told you. You should check with your doctor
or pharmacist if you are not sure.
Colestid Granules must not be taken as a dry
powder and must be mixed with a drink or taken
with liquid food. The Colestid Granules should be
mixed thoroughly with at least 100 ml of water
or another still drink such as orange or skimmed
milk. Alternatively, Colestid Granules can be taken
with soup or cereal or with pulpy fruit such as
grapefruit, provided that there is at least 100 ml or
more of liquid.

Your doctor will advise you on the amount of
Colestid Granules you should take, and when.
Most people start by taking one to two sachets
of Colestid Granules per day. Your doctor
may increase your dose each month until your
cholesterol reaches the best level for you. Do
not change the number of sachets you take
unless your doctor tells you to. Do not take
more than 6 sachets (30 grams) a day. If you are
prescribed more than two sachets per day, it may
be preferable to take Colestid Granules as two
separate doses, leaving several hours between
e.g. with breakfast and an evening meal.

Taking Colestid with other medicines

If you have other medicines to take, make sure
you take them at least one hour before or four
hours after your Colestid Granules, except if you
are taking gemfibrozil, take this at least two hours
before or after your Colestid Granules.
You may have to take Colestid Granules every
day for a long time. It is important that you stick
to your recommended diet as well as taking your
Colestid Granules.
Colestid Granules does not actually dissolve and
it therefore has a ‘gritty’ texture, especially if it is
not well mixed with the liquid you are using. The
‘grittiness’ of Colestid Granules is much more
obvious in ‘dilute’ drinks such as water or fruit
juice. In thicker mixtures such as muesli with milk,
you may not notice Colestid Granules at all. Some
people mix up Colestid Granules the night before
to improve results.


You will find more about COLESTID GRANULES
on the back of this leaflet

Use by Children

Colestid Granules will not normally be given to
children. Ask your doctor for more information if
they have prescribed Colestid Granules for a child
in your care. If children or young adults are given
this medicine, your doctor will need to check their
growth and development regularly.

If you take more Colestid Granules
than you should

Never take more Colestid Granules than your
doctor has told you. If you do, tell your doctor
because you may get constipation.

If you forget to take Colestid Granules

Don’t worry. Take your next sachet (or sachets) at
the usual time.
Do not take a double dose to make up for a
forgotten dose.

4. Possible side effects

Like all medicines, Colestid Granules can cause
side effects, although not everyone gets them.
Tell your doctor if you experience any of the
following side effects and they do not go away:
• constipation, which is usually mild and does
not last for long. Eating more fibre and drinking
plenty of fluid usually helps. Sometimes it
can be more severe and cause a blockage n
your colon. If this happens you might need
some treatment like an enema, to relieve the
blockage. Tell your doctor if you think you
have this problem. Constipation can make
piles (haemorrhoids) worse and you may
notice blood in your stools. Tell your doctor
immediately if this happens.
• stomach discomfort
• belching,
• wind,
• nausea, feeling sick
• sickness or diarrhoea.

Other side effects
Rarely, people have noticed the following side
effects, Tell your doctor immediately if any of
these happen.
• stomach ulcers and bleeding stomach ulcers.
These will cause severe stomach pains and if
these start to bleed you may pass very dark
stools or bring up blood if you are sick.
• inflammation of the gall bladder, gallstones or
yellowish skin.
• chest pain, angina-like feelings or you may feel
your heart beat speeding up.
• allergy effects like a rash, itchy skin or hives.
• aches and pains in your joints and muscles,
especially your fingers and toes. You may also
feel backache.
• headaches, some of which may feel quite
severe (migraine, sinus headache) or feel dizzy
and light-headed. You may also have difficulty
• not feel like eating, feeling tired and weak, have
a shortness of breath, or swelling of your hands
and feet.
Colestid Granules affects the way that your body
absorbs fats and some ‘fat-soluble’ vitamins
(A,D,E and K). Your doctor may give you a vitamin
supplement if they think this could be happening.
The levels of some fats and enzymes in your
blood may rise. This is usually temporary.
If any of the side effects gets serious, or if you
notice any side effects not listed in this leaflet,
please tell your doctor.

5. How to store Colestid Granules

Keep out of the reach and sight of children.
Do not use Colestid Granules after the expiry date
which is stated on the label. The expiry date refers
to the last day of the month.
Do not store above 25°C.
Medicines should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of medicines no
longer required. These measures will help to
protect the environment.

Marketing Authorisation Holder
Pharmacia Limited,
Ramsgate Road,
CT13 9NJ,


Pfizer PGM,
10 rue Bouché Thomas,
Zac Sud d’Orgemont,
49007 Angers Cedex,

More information about cholesterol

6. Further information
What Colestid Granules contains
• The active substance is colestipol

hydrochloride 5g.
The other ingredients are Colloidal
Anhydrous Silica.

If you would like any more information about
changing your lifestyle to lower your cholesterol
you can contact:
The British Heart Foundation,
14 Fitzhardinge Street,
W1H 4DH.
Tel. 020 7935 0185

What Colestid Granules looks like and
the contents of the pack
• Colestid Granules are light yellow granules
for oral suspension.

• Colestid Granules comes in boxes of

30 sachets. Each 7.5 g sachet contains
5 g of the active substance, colestipol

This leaflet was last approved in 10/2007
®Colestid is a registered trademark
- Pharmacia Limited.
Ref CL 3_3

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.