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CO-TRIAMTERZIDE TABLETS

Active substance: TRIAMTERENE

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KEEP ALL MEDICINES OUT OF THE REACH OF CHILDREN
CO-TRIAMTERZIDE TABLETS 50/25MG
BEFORE YOU TAKE YOUR MEDICINE PLEASE READ THIS LEAFLET CAREFULLY

This leaflet contains a summary of the information about your medicine, Co-Triamterzide
Tablets 50/25mg.
YOUR MEDICINE
Your medicine is in the form of a tablet. Each tablet contains two active ingredients; 50mg of
Triamterene and 25mg of Hydrochlorothiazide. Each tablet also contains lactose, sodium
starch glycollate, maize starch, microcrystalline cellulose, povidone, disodium edetate,
magnesium stearate and sunset yellow (E110).
Co-Triamterzide Tablets 50/25mg are available in containers of 100 and 500* tablets.
Your pharmacist will dispense the number of tablets prescribed by your doctor.
(*Only marketed pack sizes will feature on the printed leaflet)

HOW DOES YOUR MEDICINE WORK?
Your medicine contains TRIAMTERENE and HYDROCHLOROTHIAZIDE which both
belong to a group of drugs called DIURETICS (or ‘water’ tablets). Diuretics work by
reducing the amount of water in the body by acting on the kidneys to increase the flow of
urine. Otherwise, too much fluid in the body can raise blood pressure and overwork the
different organs of the body leading to their damage.
Product Licence Holder:
Manufacturer:

Generics [UK] Limited, Station Close, Potters Bar, Herts
EN6 1TL
Alphapharm [Pty] Ltd, Brisbane, Queensland 4300,
Australia

WHY DO YOU NEED TO TAKE YOUR MEDICINE?
There are a number of conditions that can be treated by Co-Triamterzide Tablets 50/25mg.
These conditions include:
 Mild or moderate hypertension (high blood pressure)
 Build up of fluid in the body caused by heart failure, liver or kidney disease

WHAT SHOULD YOU DO BEFORE TAKING YOUR MEDICINE?
You must tell your doctor before taking your medicine if
 You are pregnant or intend to become pregnant
 You are breastfeeding
 You have taken hydrochlorothiazide, triamterene or a similar medicine before and you
suffered an unpleasant or allergic reaction
 You have liver or kidney disease







2
You know you have a high level of potassium (hyperkalaemia) or calcium
(hypercalcaemia) in your body
You suffer from a condition called Addison’s disease
You have diabetes
You suffer from gout
You are already taking any of the following medicines:
 Medicine containing potassium
 Other diuretics eg amiloride, spironolactone
 Medicine to treat a heart condition eg digoxin, amiodarone, captopril or to lower
blood pressure eg betablockers
 Tubocurarine, a muscle relaxant
 Cholestyramine, used to lower cholesterol levels
 Corticosteroids
 Carbenoxolone

Do not take these tablets if you think you are allergic to any of the ingredients especially the
colorant sunset yellow which can cause allergic reactions eg asthma. Allergy is more
common in those people who are allergic to asprin.
WHILST TAKING YOUR TABLETS
Your doctor will give you regular blood tests if you are elderly, suffer from kidney disease or
are already taking a painkiller such as naproxen, ibuprofen.
HOW SHOULD YOU TAKE YOUR TABLETS?
Co-Triamterzide Tablets 50/25mg should not be given to children
Your doctor will prescribe a dose depending on the condition being treated.
Hypertension
The usual dose is one tablet of Co-Triamterzide taken after breakfast. This medicine may be
taken along with other medicine to treat hypertension.
To reduce a build up of fluid (oedema)
The usual starting dose is one tablet twice a day after meals. This dose may be increased to
three tablets a day until your condition improves: Your doctor will then slowly reduce your
dose to one tablet a day or two tablets every other day.
The maximum daily dose is 4 tablets of Co-Triamterzide.
If you are elderly you may be more sensitive to the effects of Co-Triamterzide: If this is the
case, your doctor will prescribe lower doses to the above to treat your condition.
If you forget to take your dose of Co-Triamterzide Tablets 50/25mg, unless it is almost
time for your next dose, take it as soon as you remember. Otherwise, if you miss a dose do
not double the next dose, just carry on as before.
If you take too much of your medicine contact your doctor immediately

3
CAN YOUR MEDICINE HAVE ANY SIDE EFFECTS?
Side effects from taking Co-Triamterzide Tablets 50/25mg may include feeling or being sick,
diarrhoea, muscle cramps, weakness, dizziness, headache, dry mouth and skin rashes.
Sometimes dehydration, rapid breathing, drowsiness, changes in urinary function and raised
levels of blood fats, may occur. Rarely sensitivity of the skin to sunlight, unusual bruising or
bleeding of the skin, sore throat with fever, feeling unusually tired and pale, yellowing of the
skin or whites of the eyes, and very rarely breathing difficulties, acute abdominal pain or
tightness of the chest may occur.
If you should suffer from any of these unwanted side effects or any undesired effect
please tell your pharmacist or doctor.
DO NOT TAKE THIS MEDICINE AFTER THE EXPIRY DATE SHOWN ON THE LABEL.

REMEMBER this medicine was prescribed by your doctor for you.
DO NOT give it to others: It may harm them.
Store in a cool dry place below 25ºC.
Date of preparation of leaflet: August 1998

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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