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Magnapen 250mg Hard Capsules

1.3 Product Information

Package leaflet: Information for the user
Magnapen® Hard Capsules
Co-fluampicil: 250mg Ampicilin/250mg Flucloxacillin
Read all of this leaflet carefully before you start using this medicine
Keep this leaflet. You may need to read it again.
If you have any further questions, please ask your doctor or nurse.
This medicine has been prescribed for you personally and you should not pass it
on to others. It may harm them, even if their symptoms are the same as yours.
The name of your medicine is Magnapen® Hard Capsules. In the rest of this leaflet it is
called Magnapen® Capsules.
In this leaflet:
What Magnapen® is and what it is used for
Before you take Magnapen® Capsules
How to take Magnapen® Capsules
Possible side effects
How to store Magnapen® Capsules
Further information

What Magnapen® is and what it is used for

Magnapen® Capsules contain two active ingredients, ampicillin and flucloxacillin
which together are known as co-fluampicil. Magnapen® Capsules are an antibiotic
medicine. They belong to the penicillin group of antibiotics and work by killing
bacteria that cause infections.
Magnapen® Capsules are used to treat a wide range of infections caused by bacteria.
These infections may affect the chest, ear, nose, throat, skin and soft tissues.
In hospital this medicine may also be used to prevent and treat infections:
• which occur after surgery
• in patients receiving treatment which affects the immune system of the blood
• associated with difficulties in childbirth (septic abortion (abortion complicated
by fever, often leading to sepsis) and puerperal fever (an infection of the
membrane of the uterus following childbirth or abortion)).

Before you take Magnapen® Capsules

Do not take Magnapen® Capsules if you:

know that you are allergic to penicillin, cephalosporins, any other antibiotic or any
of the ingredietns contained in Magnapen® Capsules (see ‘What Magnapen®
Capsules contain’ in section 6)

Magnapen 250mg Hard Capsules


1.3 Product Information

have ever had a skin rash or swelling of the face or neck when taking an antibiotic
have ever had a serious complaint, such as liver problems, when taking an

If any of the above statements apply to you, you should not be give Magnapen®
Speak to your doctor before taking Magnapen® Capsules if you:
- are being treated for kidney or liver problems
- have glandular fever
- are having blood tests because your medicine sometimes causes short-term
changes in blood cell counts.
Additional monitoring of kidney and liver function is recommended for patients on
prolonged treatment e.g. osteomyelitis (bone infection) or endocarditis (infection of
the muscle around the heart).
If any of the above apply your doctor may decide to change the dose of Magnapen®
Capsules or prescribe a different medicine.
Taking other medicines
Taking another medicine while you are taking Magnapen® Capsules can affect how it
or the other medicine works. Please inform your doctor or pharmacist if you are
taking or have recently taken any other medicines, even those you may have bought
yourself without a prescription.
Tell your doctor if you are using the following medicines (or any other
• a contraceptive pill as you will need to take extra precautions such as use of
a condom
• probenecid and allopurinol, used in the treatment of gout
• or if you are being treated with any other antibiotic
If you are required to have a urine test, please inform your doctor you are taking
Magnapen®. False positive results can occur with certain tests for sugar in the urine
(e.g. the Fehling’s test) whilst taking Magnapen®.
If you have any doubts about whether you should take this medicine then discuss
matters with your doctor before taking it.
Pregnancy and breast-feeding
You should let your doctor know if you are pregnant, think you might be pregnant or
are breast-feeding before taking this medicine. Your doctor will decide if this
medicine is suitable for you.
Important information about the sodium content of Magnapen® Capsules

Magnapen 250mg Hard Capsules

1.3 Product Information

This medicinal product contains 13.0mg of sodium per capsule. This medicinal
product contains less than 1 mmol sodium (23mg) per dose, i.e. essentially ‘sodium

How to take Magnapen® Capsules

Always take Magnapen® Capsules exactly as your doctor has told you. You should
check with your doctor or pharmacist if you are not sure.
• The dose of Magnapen® your doctor prescribes and the length of time for
which you will have to take it, will depend on your infection.
• The usual does of Magnapen® Capsules for the elderly, adults and children
over 10 years of age is one capsule four times a day. If your infection is
severe, your doctor may double this does in two capsules four times a day
• For children under 10 years of age Magnapen® Syrup should be used.
• Try to take your capsules as part of your daily routine and space the doses as
evenly as possible through the day – for example before meal times and at
bedtime. You do not need to take a dose in the middle of the night unless your
doctor has told you to do so.
• Magnapen® Capsules should be swallowed whole with a glass of water half an
hour to one hour before food. If this medicine is taken with food it may not
work as well as it should.
If you take more Magnapen® Capsules than you should
If you take too many Magnapen® Capsules contact your doctor or hospital casualty
department immediately. Take this leaflet and any remaining capsules with you.
Symptoms of an overdose include feeling sick, being sick and diarrhoea.
If you miss a dose of Magnapen® Capsules
If you forget to take a dose at the right time, take it as soon as you remember. Then
go on as before. But don’t take the next does too soon. Always try to keep the doses
evenly spaced and do not take two doses within one hour or so of each other.
If you stop taking Magnapen® Capsules
Keep taking your capsules until the prescribed course is finished. Do not stop just
because you feel better. If you stop too soon, the infection may start up again. If you
feel unwell at the end of your course of treatment tell your doctor.
Possible side effects
Like many medicines Magnapen® Capsules may cause side effects in some patients,
particularly when treatment is first stated, although not everybody gets them.
Stop taking Magnapen® Capsules and see your doctor immediately if you:
• get severe diarrhoea with bleeding or stomach pain
• notice your urine becoming darker or your faeces becoming paler
• notice your skin or the whites of your eyes turning yellow
• notice red or purple discolourations on the skin
• notice that your face is swollen and you have breathing problems

Magnapen 250mg Hard Capsules

1.3 Product Information

start to itch or get a rash
notice blistering of the skin, mouth, eyes or genitals
notice increased bleeding/bruising, pale skin or weakness (due to changes in
the levels of certain blood cells)
develp nephritis (inflammation of the kidneys that can cause swollen ankles or
high blood pressure)
develop a fever

Frequent side effects which are usually mild include
• nausea (feeling sick)
• vomiting (being sick)
• diarrhoea
Some of these reactions can be delayed for several weeks after finishing the treatment.
If you experience any side effects or feel that the medicine is affecting you badly,
contact your doctor or pharmacist.

How to store Magnapen® Capsules

Keep out of the reach and sight of children
Do not take the medicine after the expiry date printed on the pack.
The expiry date refers to the last date of the month.
Do not store above 25°C.
Store in the original container in order to protect from moisture.
Medicines should not be disposed of via wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer required. These
measures will help to protect the environment.


Further information

What Magnapen®Capsules contain
Magnapen® Capsules contain two active ingredients, ampicillin and flucloxacillin
which together are known as co-fluampicil. Each capsules contains 250mg ampicillin
as ampicillin trihydrate and 250mg of flucloxacillin as flucloxacillin sodium.
Your medicine also contains inactive ingredients. These are quinoline yellos (E104),
patent blue V (E131), iron oxides (E172), titanium dioxide (E171), magnesium
stearate (E572) and gelatin.
Contents of the pack
Magnapen® Capsules are available in two pack sizes, 28 and 100.

Magnapen 250mg Hard Capsules

1.3 Product Information

The most common pack of capsules you are likely to receive is 28 capsules, but this
may vary depending on the length of treatment your doctor has prescribed.
Marketing Authorisation Holder and Maanufacturer
Marketing Authorisation Holder: Wockhardt Ltd, Ash Road North, Wrexham LL13
Manufacturer: Laboratorio Reig Jofre, S.A. c/Jarama, s/n. (Poligono Industrial)
45007 Toledo, Spain.
Other formats:
To listen to or request a copy of this leaflet in Braille, large print or audio please call,
free of charge: 0800 198 5000 (UK Only)
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Product Name

Reference Number

Magnapen® Hard Capsules


This is a service provided by the Royal National Institute of Blind People.
Date of leaflet preparation: Oct 2009

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.