CO-CARELDOPA 25/100MG TABLETS

Active substance: LEVODOPA

View full screen / Print PDF » Download PDF ⇩

Transcript
Sinemet ® Plus Tablets

Ref: 0062/2009121/F

(carbidopa / levodopa)
Patient Information Leaflet
Read all of this leaflet carefully before you start taking this
medicine.

* Keep this leaflet. You may need to read it again.
* If you have any further questions, ask your doctor or pharmacist.
* This medicine has been prescribed for you. Do not pass it on to others.
It may harm them, even if their symptoms are the same as yours.

* If any of the side effects gets serious, or if you notice any side effects not
listed in this leaflet, please tell your doctor or pharmacist.

Your medicine is called Sinemet Plus Tablets and will be referred to as
Sinemet throughout the rest of this leaflet. Please note that the leaflet also
contains information about other strengths of the medicine, Sinemet
10mg/100mg Tablets and Sinemet 25mg/250mg Tablets.
In this leaflet:
1 What Sinemet is and what it is used for
2 Before you take Sinemet
3 How to take Sinemet
4 Possible side effects
5 How to store Sinemet
6 Further information

1

What Sinemet is and what it is used for

Sinemet improves the signs of Parkinson’s disease. Parkinson's disease is a
long-term illness where:
* you become slow and unsteady
* your muscles feel stiff
* you may develop shaking or trembling (called ‘tremor’).
If not treated, Parkinson's disease can make it hard for you to continue your
normal daily activities.
Sinemet contains two different medicines called: levodopa and carbidopa.
* levodopa turns into a material called ‘dopamine’ in your brain.
The dopamine helps to improve the signs of your Parkinson’s disease.
* carbidopa belongs to a group of medicines called ‘aromatic amino acid
decarboxylase inhibitors’. It helps levodopa work more effectively by
slowing the speed at which levodopa is broken down in your body.

2

Before you take Sinemet

Do not take Sinemet if:
* you are allergic (hypersensitive) to carbidopa or levodopa or any of the
other ingredients of Sinemet (listed in Section 6)
* you have ever had skin cancer or you have any unusual moles which have
not been examined by your doctor
* you are taking certain medicines called ‘MAOIs’ (Monoamine Oxidase
Inhibitors) used for depression. You need to stop using these medicines at
least two weeks before you start Sinemet (see also under ‘Taking other
medicines’ below).
* you have a condition called ‘narrow-angle glaucoma’ that may cause a
sudden build up of pressure in the eye
* you have a severe mental disorder
* you are pregnant, might become pregnant, or are breast-feeding.
Do not take Sinemet if any of the above apply to you. If you are not sure,
talk to your doctor or pharmacist before taking Sinemet.
Take special care with Sinemet
Check with your doctor or pharmacist before taking your medicine if:
* you have a history of fits (convulsions)
* you have had an ulcer in your gut (called ‘duodenal’ or ‘peptic ulcer’) or
have vomited blood
* you have had a heart attack, heart beat problems, circulation or breathing
problems
* you have had kidney, liver or hormonal problems
* you have had depression or other mental problems
* you have a condition called ‘chronic wide-angle glaucoma’ that may cause
a build up of pressure in the eye. You will need to have regular checks on
the pressure in your eye.
* you sometimes have sudden sleep attacks or sometimes feel very sleepy
* you are due to have surgery.
* Tell your doctor if you or your family/carer notices you are developing
urges or cravings to behave in ways that are unusual for you or you
cannot resist the impulse, drive or temptation to carry out certain activities
that could harm yourself or others. These behaviours are called impulse
control disorders and can include addictive gambling, excessive eating or
spending, an abnormally high sex drive or an increase in sexual thoughts
or feelings. Your doctor may need to review your treatments.
If you are not sure if any of the above apply to you, talk to your doctor or
pharmacist before taking Sinemet.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken
any other medicines, including medicines obtained without a prescription.
This includes herbal medicines. This is because Sinemet can affect the way
some other medicines work. Also some other medicines can affect the way
Sinemet works.
In particular tell your doctor or pharmacist if you are taking any of the
following medicines:
* Medicines for Parkinson’s disease containing levodopa:
- If they are ‘slow release’, you will need to wait 24 hours after your
last dose before starting Sinemet.
- If they are ‘normal release’, you will need to wait 12 hours after
your last dose before starting Sinemet.
- Tell the doctor or pharmacist even if you have only taken them in
the past.
Medicines for Parkinson’s disease which do not contain levodopa will
usually be continued. However, your dose may be changed.
* Medicines for mental problems (including depression), tuberculosis (TB),
high blood pressure, muscle spasms, epilepsy or to treat low iron. Your
dose may need to be changed.
* Medicines called ‘MAOIs’ (see also ‘Do not take Sinemet if’).
* Anticholinergic medicines (such as orphenadrine, trihexyphenidyl,
benzatropine and procyclidine). Your dose may need to be changed.
* Phenytoin which is used to treat fits (convulsions).
* Papaverine which is used to treat impotence in men.
If you are not sure if any of the above apply to you, talk to your doctor or
pharmacist before taking this medicine. Your doctor or pharmacist has a
more complete list of medicines to avoid while taking Sinemet.
Tests while you are taking Sinemet
This medication can affect some laboratory tests that your doctor may
perform on blood or urine samples. Please remind your doctor if you are
taking Sinemet and are having any tests.
Taking Sinemet with food and drink
Try to avoid taking your tablets with a heavy meal. If your diet contains too
much protein (meat, eggs, milk, cheese) Sinemet may not work as well as it
should.
Pregnancy and breast-feeding
Do not take Sinemet if you are pregnant, might become pregnant or are
breast-feeding. Levodopa, one of the substances in Sinemet, is passed into
human milk. Ask your doctor or pharmacist for advice before taking any
medicine, if you are pregnant or breast-feeding.
Driving and using machines
* Sinemet affects different people in different ways. Some people have side
effects which affect their ability to drive or use tools or machines. (see
Section 4 Possible side effects). Do not drive or use tools or machines if
you get these effects.
* Sinemet can also make you sleepy or cause 'sudden sleep attacks'. If this
happens to you, you must not drive or use tools or machines. Your doctor
will tell you if you can start driving again if these attacks stop.

3

How to take Sinemet

Always take Sinemet exactly as your doctor has told you. You should check
with your doctor or pharmacist if you are not sure.
Taking this medicine
* Take this medicine by mouth.
* Although your medicine can have an effect after one day, it may take up to
seven days to work.
* Take them at regular time intervals according to your doctor's instructions.
* Do not change the times at which you take your tablets or take any other
medicines for Parkinson's disease without first consulting your doctor.
* Try to avoid taking your tablets with a heavy meal.
If you have not had levodopa before
The usual starting dose is:
* for Sinemet-Plus Tablets: one tablet three times a day.
* for Sinemet 10 mg/100 mg Tablets: one tablet three or four times a day.
If you have had levodopa before
* your doctor will ask you to stop taking your medicine for Parkinson’s
disease before you start taking Sinemet.
The usual starting dose is:

* for Sinemet Plus Tablets and Sinemet 25 mg/250 mg Tablets: one tablet
three or four times a day.

* for Sinemet 10 mg/100 mg Tablets it will depend on what you were taking
before.

More than one Sinemet product may be prescribed by your doctor.
If you have been given different Sinemet tablets to take make sure that you
are taking the correct one at the right time.

Sinemet ® Plus Tablets

Ref: 0062/200912/1/B

(carbidopa / levodopa)
Patient Information Leaflet (continued)
Children under 18 years of age
Sinemet is not suitable for children under the age of 18 years.
If you take more Sinemet than you should
If you take too many tablets see your doctor immediately.
If you forget to take Sinemet
Do not take a double dose to make up for a forgotten dose.
If you stop taking Sinemet
Do not stop taking Sinemet or change your dose without talking to your
doctor first. When you stop taking Sinemet the following can occur: stiff
muscles, high temperature (fever) and mental changes.
If you have any further questions on the use of this product, ask your doctor
or pharmacist.

4

Possible side effects

Like all medicines, Sinemet can cause side effects, although not everybody
gets them.
Stop taking Sinemet and see your doctor straight away, if you notice
any of the following side effects:
* allergic reaction, the signs may include hives (nettle rash), itching, rash,
swelling of your face, lips, tongue or throat. This may cause difficulty in
breathing or swallowing
* chest pain
* uneven (irregular) heart beat or palpitations
* dizziness on standing-up quickly
* bleeding from your gut which may be seen as blood in your faeces or
darkened faeces (gastro-intestinal bleeding)
* blood problems, the signs may include pale skin (pallor), tiredness, fever,
sore throat or mild bruising and prolonged bleeding after injury
* stiff muscles, high fever
* mental changes including delusions, hallucinations and depression
* fits (convulsions).
The most common side effects are
* abnormal movements such as twitching or spasms (which may or may not
be like your Parkinson's symptoms)
* nausea.
Other side effects include
* fainting, anorexia, high blood pressure
* inflammation of the veins, being sick (vomiting) diarrhoea, discoloration of
urine, sweat or saliva
* on-off phenomenon, characteristic of some people with long-standing
Parkinson’s disease. This is when you can have unpredictable changes
from being mobile - “on” - to a sudden inability to move - “off”. “Off” to “on”
can occur just as suddenly.
* dizziness; sleepiness (including excessive drowsiness or sudden sleep
onset episodes), pins and needles
* dream abnormalities, confusion, feeling agitated, increased sexual drive,
shortness of breath, hair loss
* an excessive desire to gamble.
Side effects that have been reported with medicines containing
levodopa.
These may be experienced when taking Sinemet.
Nervous system:
* loss of control over the voluntary movements of everyday life
* numbness, increased hand tremor, muscle twitching, muscle cramp,
irregular movement of jaw muscles resulting in difficulty opening the
mouth
* difficulty sleeping, feeling anxious or high, falling over and abnormal
walking patterns
* headache
Eyes:
* drooping eyelid and dilated pupil
* changes in vision, irregular movement of the eye
Digestive system:
* indigestion, dry mouth, bitter taste
* swelling of the salivary glands, difficulty swallowing, grinding of the teeth
* hiccups, abdominal pain and distress, constipation, wind
* burning sensation of the tongue.
Sexual:
* persistent abnormal erection of the penis
Urinary:
* difficulty passing urine or incontinence (inability to control urine flow);

Skin:
* changed patches of pigmented skin, including, irritated or irregular moles,
or moles in which you have noticed changes (melanoma)
General:
* weight gain or loss, swelling in the limbs
* flushing, hot flushes, increased sweating
* feeling weak, faint or tired
* hoarseness, general feeling of being unwell
* increased energy or activity, unusual breathing pattern
You may experience the following side effects:
* inability to resist the impulse to perform an action that could be harmful,
which may include:
-Strong impulse to gamble excessively despite serious personal or family
consequences.
-Altered or increased sexual interest and behaviour of significant concern
to you or to others, for example, an increased sexual drive.
-uncontrollable excessive shopping or spending
-binge eating (eating large amounts of food in a short time period) or
compulsive eating (eating more food than normal and more than is
needed to satisfy your hunger)
Tell your doctor if you experience any of these behaviours; they will
discuss ways of managing or reducing the symptoms
If any symptoms persist or you experience any other side effects please tell
your doctor or pharmacist. It will help if you make a note of what you
experienced, when it started and how long it lasted.

5

How to store Sinemet

* KEEP THIS MEDICINE OUT OF THE SIGHT AND REACH OF
CHILDREN.

* Do not store above 25ºC.
* Store in a dry place. Protect from light.
Expiry Date
Do not use this medicine after the expiry date shown on the carton label or
blister strip. If your doctor tells you to stop taking this medicine, return any
unused tablets to your pharmacist (chemist) for safe disposal. Only keep this
medicine if your doctor tells you to. If your tablets become discoloured or
show any other signs of deterioration, consult your pharmacist (chemist) who
will tell you what to do.
Important
This medicine is for you. Only a doctor can prescribe it. This leaflet does not
contain everything about this medicine, if you have any questions or are not
sure about anything then contact your doctor or pharmacist. He/she will have
additional information about this medicine and will be able to advise you.

6

Further information

Your medicine
Your medicine is called Sinemet Plus Tablets. They are available in blister
packs of 100 tablets (10 x blisters of 10 tablets).
The tablets are yellow and oval shaped, marked with 650 and a break line
on one side and plain on the other.
What is in your medicine
Each tablet contains carbidopa monohydrate, equivalent to 25mg anhydrous
carbidopa & 100mg levodopa.
Sinemet Plus Tablets also contain the following: pre-gelatinised starch,
starch, microcrystalline cellulose, magnesium stearate & quinoline yellow.
Who manufactured your medicine
The tablets are manufactured by Frosst Ibérica, S.A., Via Complutense, 140,
28805 Alcalá de Henares, Madrid, Spain and are procured from within the
EU and repackaged by the Product Licence Holder: Lexon (UK) Limited, Unit
18, Oxleasow Road, East Moons Moat, Redditch, Worcestershire, B98 0RE.

POM

PL No: 15184/0062

Revision date: 20/09/12
Sinemet is a registered trademark of Merck & Co Inc.

Blind or partially sighted?
Is this leaflet hard to see or read?
Phone Lexon (UK) Limited, Tel: 01527 505414
for help.

Ref: 0062/200912/2/F

Co-Careldopa 25/100mg Tablets
(carbidopa / levodopa)
Patient Information Leaflet
Read all of this leaflet carefully before you start taking this
medicine.

* Keep this leaflet. You may need to read it again.
* If you have any further questions, ask your doctor or pharmacist.
* This medicine has been prescribed for you. Do not pass it on to others.
It may harm them, even if their symptoms are the same as yours.

* If any of the side effects gets serious, or if you notice any side effects not
listed in this leaflet, please tell your doctor or pharmacist.

Your medicine is called Co-Careldopa 25/100mg Tablets and will be referred
to as Co-Careldopa throughout the rest of this leaflet. Please note that the
leaflet also contains information about other strengths of the medicine,
Co-Careldopa 10mg/100mg Tablets and Co-Careldopa 25mg/250mg Tablets.
In this leaflet:
1 What Co-Careldopa is and what it is used for
2 Before you take Co-Careldopa
3 How to take Co-Careldopa
4 Possible side effects
5 How to store Co-Careldopa
6 Further information

1

What Co-Careldopa is and what it is used for

Co-Careldopa improves the signs of Parkinson’s disease. Parkinson's
disease is a long-term illness where:
* you become slow and unsteady
* your muscles feel stiff
* you may develop shaking or trembling (called ‘tremor’).
If not treated, Parkinson's disease can make it hard for you to continue your
normal daily activities.
Co-Careldopa contains two different medicines called: levodopa and
carbidopa.
* levodopa turns into a material called ‘dopamine’ in your brain.
The dopamine helps to improve the signs of your Parkinson’s disease.
* carbidopa belongs to a group of medicines called ‘aromatic amino acid
decarboxylase inhibitors’. It helps levodopa work more effectively by
slowing the speed at which levodopa is broken down in your body.

2

Before you take Co-Careldopa

Do not take Co-Careldopa if:
* you are allergic (hypersensitive) to carbidopa or levodopa or any of the
other ingredients of Co-Careldopa (listed in Section 6)
* you have ever had skin cancer or you have any unusual moles which have
not been examined by your doctor
* you are taking certain medicines called ‘MAOIs’ (Monoamine Oxidase
Inhibitors) used for depression. You need to stop using these medicines at
least two weeks before you start Co-Careldopa (see also under ‘Taking
other medicines’ below).
* you have a condition called ‘narrow-angle glaucoma’ that may cause a
sudden build up of pressure in the eye
* you have a severe mental disorder
* you are pregnant, might become pregnant, or are breast-feeding.
Do not take Co-Careldopa if any of the above apply to you. If you are not
sure, talk to your doctor or pharmacist before taking Co-Careldopa.
Take special care with Co-Careldopa
Check with your doctor or pharmacist before taking your medicine if:
* you have a history of fits (convulsions)
* you have had an ulcer in your gut (called ‘duodenal’ or ‘peptic ulcer’) or
have vomited blood
* you have had a heart attack, heart beat problems, circulation or breathing
problems
* you have had kidney, liver or hormonal problems
* you have had depression or other mental problems
* you have a condition called ‘chronic wide-angle glaucoma’ that may cause
a build up of pressure in the eye. You will need to have regular checks on
the pressure in your eye.
* you sometimes have sudden sleep attacks or sometimes feel very sleepy
* you are due to have surgery.
* Tell your doctor if you or your family/carer notices you are developing
urges or cravings to behave in ways that are unusual for you or you
cannot resist the impulse, drive or temptation to carry out certain activities
that could harm yourself or others. These behaviours are called impulse
control disorders and can include addictive gambling, excessive eating or
spending, an abnormally high sex drive or an increase in sexual thoughts
or feelings. Your doctor may need to review your treatments.
If you are not sure if any of the above apply to you, talk to your doctor or
pharmacist before taking Co-Careldopa.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken
any other medicines, including medicines obtained without a prescription.
This includes herbal medicines. This is because Co-Careldopa can affect the
way some other medicines work. Also some other medicines can affect the
way Co-Careldopa works.
In particular tell your doctor or pharmacist if you are taking any of the
following medicines:
* Medicines for Parkinson’s disease containing levodopa:
- If they are ‘slow release’, you will need to wait 24 hours after your
last dose before starting Co-Careldopa.
- If they are ‘normal release’, you will need to wait 12 hours after
your last dose before starting Co-Careldopa.
- Tell the doctor or pharmacist even if you have only taken them in
the past.
Medicines for Parkinson’s disease which do not contain levodopa will
usually be continued. However, your dose may be changed.
* Medicines for mental problems (including depression), tuberculosis (TB),
high blood pressure, muscle spasms, epilepsy or to treat low iron. Your
dose may need to be changed.
* Medicines called ‘MAOIs’ (see also ‘Do not take Co-Careldopa if’).
* Anticholinergic medicines (such as orphenadrine, trihexyphenidyl,
benzatropine and procyclidine). Your dose may need to be changed.
* Phenytoin which is used to treat fits (convulsions).
* Papaverine which is used to treat impotence in men.
If you are not sure if any of the above apply to you, talk to your doctor or
pharmacist before taking this medicine. Your doctor or pharmacist has a
more complete list of medicines to avoid while taking Co-Careldopa.
Tests while you are taking Co-Careldopa
This medication can affect some laboratory tests that your doctor may
perform on blood or urine samples. Please remind your doctor if you are
taking Co-Careldopa and are having any tests.
Taking Co-Careldopa with food and drink
Try to avoid taking your tablets with a heavy meal. If your diet contains too
much protein (meat, eggs, milk, cheese) Co-Careldopa may not work as well
as it should.
Pregnancy and breast-feeding
Do not take Co-Careldopa if you are pregnant, might become pregnant or
are breast-feeding. Levodopa, one of the substances in Co-Careldopa, is
passed into human milk. Ask your doctor or pharmacist for advice before
taking any medicine, if you are pregnant or breast-feeding.
Driving and using machines
* Co-Careldopa affects different people in different ways. Some people have
side effects which affect their ability to drive or use tools or machines. (see
Section 4 Possible side effects). Do not drive or use tools or machines if
you get these effects.
* Co-Careldopa can also make you sleepy or cause 'sudden sleep attacks'.
If this happens to you, you must not drive or use tools or machines. Your
doctor will tell you if you can start driving again if these attacks stop.

3

How to take Co-Careldopa

Always take Co-Careldopa exactly as your doctor has told you. You should
check with your doctor or pharmacist if you are not sure.
Taking this medicine
* Take this medicine by mouth.
* Although your medicine can have an effect after one day, it may take up to
seven days to work.
* Take them at regular time intervals according to your doctor's instructions.
* Do not change the times at which you take your tablets or take any other
medicines for Parkinson's disease without first consulting your doctor.
* Try to avoid taking your tablets with a heavy meal.
If you have not had levodopa before
The usual starting dose is:
* for Co-Careldopa 25/100mg Tablets: one tablet three times a day.
* for Co-Careldopa 10 mg/100 mg Tablets: one tablet three or four times a
day.
If you have had levodopa before
your doctor will ask you to stop taking your medicine for Parkinson’s
disease before you start taking Co-Careldopa.

*

The usual starting dose is:

* for Co-Careldopa 25/100mg Tablets and Co-Careldopa 25 mg/250 mg
*

Tablets: one tablet three or four times a day.
for Co-Careldopa 10 mg/100 mg Tablets it will depend on what you were
taking before.

More than one Co-Careldopa product may be prescribed by your doctor.
If you have been given different Co-Careldopa tablets to take make sure that
you are taking the correct one at the right time.

Ref: 0062/200912/2/B

Co-Careldopa 25/100mg Tablets
(carbidopa / levodopa)
Patient Information Leaflet (continued)
Children under 18 years of age
Co-Careldopa is not suitable for children under the age of 18 years.
If you take more Co-Careldopa than you should
If you take too many tablets see your doctor immediately.
If you forget to take Co-Careldopa
Do not take a double dose to make up for a forgotten dose.
If you stop taking Co-Careldopa
Do not stop taking Co-Careldopa or change your dose without talking to your
doctor first. When you stop taking Co-Careldopa the following can occur: stiff
muscles, high temperature (fever) and mental changes.
If you have any further questions on the use of this product, ask your doctor
or pharmacist.

4

Possible side effects

Like all medicines, Co-Careldopa can cause side effects, although not
everybody gets them.
Stop taking Co-Careldopa and see your doctor straight away, if you
notice any of the following side effects:
* allergic reaction, the signs may include hives (nettle rash), itching, rash,
swelling of your face, lips, tongue or throat. This may cause difficulty in
breathing or swallowing
* chest pain
* uneven (irregular) heart beat or palpitations
* dizziness on standing-up quickly
* bleeding from your gut which may be seen as blood in your faeces or
darkened faeces (gastro-intestinal bleeding)
* blood problems, the signs may include pale skin (pallor), tiredness, fever,
sore throat or mild bruising and prolonged bleeding after injury
* stiff muscles, high fever
* mental changes including delusions, hallucinations and depression
* fits (convulsions).
The most common side effects are
* abnormal movements such as twitching or spasms (which may or may not
be like your Parkinson's symptoms)
* nausea.
Other side effects include
* fainting, anorexia, high blood pressure
* inflammation of the veins, being sick (vomiting) diarrhoea, discoloration of
urine, sweat or saliva
* on-off phenomenon, characteristic of some people with long-standing
Parkinson’s disease. This is when you can have unpredictable changes
from being mobile - “on” - to a sudden inability to move - “off”. “Off” to “on”
can occur just as suddenly.
* dizziness; sleepiness (including excessive drowsiness or sudden sleep
onset episodes), pins and needles
* dream abnormalities, confusion, feeling agitated, increased sexual drive,
shortness of breath, hair loss
* an excessive desire to gamble.
Side effects that have been reported with medicines containing
levodopa.
These may be experienced when taking Co-Careldopa.
Nervous system:
* loss of control over the voluntary movements of everyday life
* numbness, increased hand tremor, muscle twitching, muscle cramp,
irregular movement of jaw muscles resulting in difficulty opening the
mouth
* difficulty sleeping, feeling anxious or high, falling over and abnormal
walking patterns
* headache
Eyes:
* drooping eyelid and dilated pupil
* changes in vision, irregular movement of the eye
Digestive system:
* indigestion, dry mouth, bitter taste
* swelling of the salivary glands, difficulty swallowing, grinding of the teeth
* hiccups, abdominal pain and distress, constipation, wind
* burning sensation of the tongue.
Sexual:
* persistent abnormal erection of the penis
Urinary:
* difficulty passing urine or incontinence (inability to control urine flow);

Skin:

* changed patches of pigmented skin, including, irritated or irregular moles,
or moles in which you have noticed changes (melanoma)

General:
* weight gain or loss, swelling in the limbs
* flushing, hot flushes, increased sweating
* feeling weak, faint or tired
* hoarseness, general feeling of being unwell
* increased energy or activity, unusual breathing pattern
You may experience the following side effects:
* inability to resist the impulse to perform an action that could be harmful,
which may include:
-Strong impulse to gamble excessively despite serious personal or family
consequences.
-Altered or increased sexual interest and behaviour of significant concern
to you or to others, for example, an increased sexual drive.
-uncontrollable excessive shopping or spending
-binge eating (eating large amounts of food in a short time period) or
compulsive eating (eating more food than normal and more than is
needed to satisfy your hunger)
Tell your doctor if you experience any of these behaviours; they will
discuss ways of managing or reducing the symptoms
If any symptoms persist or you experience any other side effects please tell
your doctor or pharmacist. It will help if you make a note of what you
experienced, when it started and how long it lasted.

5

How to store Co-Careldopa

* KEEP THIS MEDICINE OUT OF THE SIGHT AND REACH OF
CHILDREN.

* Do not store above 25ºC.
* Store in a dry place. Protect from light.
Expiry Date
Do not use this medicine after the expiry date shown on the carton label or
blister strip. If your doctor tells you to stop taking this medicine, return any
unused tablets to your pharmacist (chemist) for safe disposal. Only keep this
medicine if your doctor tells you to. If your tablets become discoloured or
show any other signs of deterioration, consult your pharmacist (chemist) who
will tell you what to do.
Important
This medicine is for you. Only a doctor can prescribe it. This leaflet does not
contain everything about this medicine, if you have any questions or are not
sure about anything then contact your doctor or pharmacist. He/she will have
additional information about this medicine and will be able to advise you.

6

Further information

Your medicine
Your medicine is called Co-Careldopa 25/100mg Tablets. They are available
in blister packs of 100 tablets (10 x blisters of 10 tablets).
The tablets are yellow and oval shaped, marked with 650 and a break line
on one side and plain on the other.
What is in your medicine
Each tablet contains carbidopa monohydrate, equivalent to 25mg anhydrous
carbidopa & 100mg levodopa.
Co-Careldopa also contain the following: pre-gelatinised starch, starch,
microcrystalline cellulose, magnesium stearate & quinoline yellow.
Who manufactured your medicine
The tablets are manufactured by Frosst Ibérica, S.A., Via Complutense, 140,
28805 Alcalá de Henares, Madrid, Spain and are procured from within the
EU and repackaged by the Product Licence Holder: Lexon (UK) Limited, Unit
18, Oxleasow Road, East Moons Moat, Redditch, Worcestershire, B98 0RE.

POM

PL No: 15184/0062

Revision date: 20/09/12

Blind or partially sighted?
Is this leaflet hard to see or read?
Phone Lexon (UK) Limited, Tel: 01527 505414
for help.

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Hide
(web1)