AMOXIL CAPSULES 250MG
Active substance: AMOXYCILLIN TRIHYDRATE
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Amoxil Capsules 250 mg and 500 mg
PHARMA CODE READING DIRECTION
amoxicillin
PHARMA CODE READING DIRECTION
Package Leaflet: Information for the User
Amoxil Capsules 250 mg and 500 mg
amoxicillin
Read all of this leaflet carefully before you start taking this medicine.
Keepthisleaflet.Youmayneedtoreaditagain. Ifyouhaveanyfurtherquestions,askyourdoctor orpharmacist. Thismedicineisusuallyprescribedforadultsand forchildrenwhoareabletoswallowcapsules.Do notpassitontoothers.Itmayharmthem,evenif theirsymptomsarethesameasyours. Ifanyofthesideeffectsgetsserious,orifyou noticeanysideeffectsnotlistedinthisleaflet, pleasetellyourdoctororpharmacist.
Ifyouaretakingprobenecid(usedforgout), yourdoctormaydecidetoadjustyourdoseof Amoxil. Ifmedicinestohelpstopbloodclots(suchas warfarin)aretakenwithAmoxilthenextrablood testsmaybeneeded. Amoxilmaystopthecontraceptivepillworking. Youwillneedtouseextracontraceptiveprecautions, suchasusingacondom.Ifyouneedanyadvice, talktoyourdoctororpharmacist.
Pregnancy and breast-feeding
Askyourdoctororpharmacistforadvicebefore takinganymedicineifyouthinkyoumightbeorif youarepregnant,orifyouarebreast-feeding.
3 How to take Amoxil
AlwaystakeAmoxilexactlyasyourdoctorhastold you.Youshouldcheckwithyourdoctoror pharmacistifyouarenotsure.
In this leaflet:
1 WhatAmoxilisandwhatitisusedfor 2 BeforeyoutakeAmoxil 3 HowtotakeAmoxil 4 Possiblesideeffects 5 HowtostoreAmoxil 6 Furtherinformation
When taking Amoxil
Swallowthecapsuleswholewithaglassofwater atthestartofamealorslightlybefore Spacethedosesevenlyduringtheday,atleast 4hoursapart Nevertake2dosesin1hour Themaximumrecommendeddoseis6gperday givenas2x3gdoses. Theusualdoseis: Children weighing less than 40 kgwhoareableto swallowcapsules Alldosesareworkedoutdependingonthechilds bodyweightinkilograms. YourdoctorwilladviseyouhowmuchAmoxilyou shouldgivetoyourbabyorchild. Usualdose40mgto90mgforeachkilogramof bodyweightaday,givenintwoorthreedivided doses.
1 What Amoxil is and what it is used for
What Amoxil is
AmoxilCapsules250mgand500mg(calledAmoxil inthisleaflet)areantibiotics.Thecapsulescontaina medicinecalledamoxicillin.Thisbelongstoagroup ofmedicinescalledpenicillins.
What Amoxil is used for
Amoxilisusedtotreatinfectionsindifferentparts ofthebodycausedbybacteria.Itisalsousedtostop infectionswhenyouhaveatoothremovedorother surgery.Amoxilmayalsobeusedincombination withothermedicinestotreatstomachulcers.
Adults, elderly patients and children weighing more than 40 kg
Standard dose:1x250mgcapsule3timesaday. Severe infections:1x500mgcapsule3timesa day. Severe or recurrent chest infection: 3g(6x500mgcapsules)twiceaday. Urinary tract (water) infection: 2x3gdoses(6x500mgcapsules) with10to12hoursbetweeneachdose. Dental abscess (infection under the gums and teeth):2x3gdoses(6x500mgcapsules)with 8hoursbetweeneachdose. Gonorrhoea (a sexually transmitted infection): 1x3gdose(6x500mgcapsules). Stomach ulcers:1x750mgdose(3x250mg capsulesor1x500mgcapsuleand1x250mg capsule)or1x1gdose(2x500mgcapsules)twice adayfor7dayswithotherantibiotics.
2 Before you take Amoxil
Do not take Amoxil if you:
areallergic(hypersensitive)toamoxicillin, penicillinoranyoftheotheringredientsof Amoxil(listedinsection6) haveeverhadanallergic(hypersensitive)reaction toanyantibiotic.Thiscanincludeaskinrashor swellingofthefaceorneck. DonottakeAmoxilifanyoftheaboveapply.Ifyou arenotsure,talktoyourdoctororpharmacist beforetakingAmoxil.
Take special care with Amoxil
Checkwithyourdoctororpharmacistbeforetaking thismedicineifyou: haveglandularfever arebeingtreatedforkidneyproblems arenotpassingwaterregularly. Ifyouarenotsureifanyoftheaboveapplytoyou, talktoyourdoctororpharmacistbeforetakingAmoxil.
To stop infection during surgery
Thedosewillvaryaccordingtothetypeof surgery.Othermedicinesmayalsobegivenatthe sametime. Yourdoctor,pharmacistornursecangiveyou moredetails.
Having urine or blood tests
Ifyouarehavingtestsonyourwater(urineglucose tests)orbloodtestsforliverfunction,letthedoctor ornurseknowthatyouareonAmoxil.Thisis becauseAmoxilcanaffecttheresultsofthesetests.
Kidney problems
Ifyouhavekidneyproblemsthedosemightbe lowerthantheusualdose.
If you take too much Amoxil
IfyouhavetoomuchAmoxil,signsmightbean upsetstomach(feelingsick,beingsickordiarrhoea) orcrystalsintheurine,whichmaybeseenascloudy urine,orproblemspassingurine.Talktoyourdoctor assoonaspossible.Takethemedicinetoshowthe doctor.
Taking other medicines
Pleasetellyourdoctororpharmacistifyouare takingorhaverecentlytakenanyothermedicines. Thisincludesmedicinesthatcanbeboughtwithout aprescriptionandherbalmedicines.Thisisbecause Amoxilcanaffectthewaysomeothermedicines work.Alsosomeothermedicinescanaffecttheway Amoxilworks. Ifyouaretakingallopurinol(usedforgout)with Amoxil,itmaybemorelikelythatyoullhavean allergicskinreaction.
If you forget to take Amoxil
Ifyouforgettotakeadosedontworry,takeitas soonasyouremember. Donttakethenextdosetoosoon,waitabout 4hoursbeforetakingthenextdose.
How long should you take Amoxil for?
KeeptakingAmoxiluntilthetreatmentisfinished, evenifyoufeelbetter.Youneedeverydoseto helpfighttheinfection.Ifsomebacteriasurvive theycancausetheinfectiontocomeback. Treatmentshouldbecontinuedfor2to3days afterthesymptomshavegone. DonottakeAmoxilformorethan2weeks.Ifyou stillfeelunwellyoushouldgobacktoseethedoctor. Thrush(ayeastinfectionofmoistareasofthebody) maydevelopifAmoxilisusedforalongtime.Ifthis occursandyouhavebeentakingAmoxilforlonger thanrecommended,tellyourdoctor. Ifyouhaveanyfurtherquestionsontheuseofthis product,askyourdoctororpharmacist.
4 Possible side effects
Likeallmedicines,Amoxilcancausesideeffects, althoughnoteverybodygetsthem.Thefollowing sideeffectsmayhappenwiththismedicine. Stop taking Amoxil and see a doctor straight away, if you notice any of the following serious side effects you may need urgent medical treatment: Thefollowingareveryrare(affectslessthan1in 10,000people) allergicreactions,thesignsmayinclude:skin itchingorrash,swellingoftheface,lips,tongue, bodyorbreathingdifficulties.Thesecanbeserious andoccasionallydeathshaveoccurred rashorpinpointflatredroundspotsunderthe skinsurfaceorbruisingoftheskin.Thisisdueto inflammationofbloodvesselwallsduetoan allergicreaction.Itcanbeassociatedwithjoint pain(arthritis)andkidneyproblems adelayedallergicreactioncanoccurusually7to 12daysafterhavingAmoxil,somesignsinclude: rashes,fever,jointpainsandenlargementofthe lymphnodesespeciallyunderthearms askinreactionknownaserythemamultiforme whereyoumaydevelop:itchyreddishpurple patchesontheskinespeciallyonthepalmsofthe handsorsolesofthefeet,hive-likeraised swollenareasontheskin,tenderareasonthe surfacesofthemouth,eyesandprivateparts. Youmayhaveafeverandbeverytired othersevereskinreactionscaninclude:changesin skincolour,bumpsundertheskin,blistering, pustules,peeling,redness,pain,itching,scaling. Thesemaybeassociatedwithfever,headaches andbodyaches hightemperature(fever),chills,asorethroator othersignsofaninfection,orifyoubruiseeasily. Thesemaybesignsofaproblemwithyour bloodcells inflammationofthelargebowel(colon) withdiarrhoeasometimescontainingblood, painandfever seriousliversideeffectsmayoccurwhichareoften reversible.Theyaremainlyassociatedwithpeople havingtreatmentoveralongperiod,malesand theelderly.Youmusttellyourdoctorurgentlyif youget: - severediarrhoeawithbleeding - blisters,rednessorbruisingoftheskin - darkerurineorpalerstools - yellowingoftheskinorthewhitesoftheeyes (jaundice).Seealsoanaemiabelowwhichmight resultinjaundice. Thesecanhappenwhenhavingthemedicineor foruptoseveralweeksafter.
kidneyproblems fits(convulsions),seeninpatientsonhighdosesor withkidneyproblems dizziness hyperactivity crystalsintheurine,whichmaybeseenascloudy urine,ordifficultyordiscomfortinpassingurine. Makesureyoudrinkplentyoffluidstoreducethe chanceofthesesymptoms teethmayappearstained,usuallyreturningto normalwithbrushing(thishasbeenreportedin children) thetonguemaychangetoyellow,brownorblack anditmayhaveahairyappearance anexcessivebreakdownofredbloodcellscausing aformofanaemia.Signsinclude:tiredness, headaches,shortnessofbreath,dizziness,looking paleandyellowingoftheskinandthewhitesof theeyes thebloodmaytakelongertoclotthanitnormally would.Youmaynoticethisifyouhavea nosebleedorcutyourself. Ifanyofthesideeffectsgetsserious,orifyouhave anysideeffectsnotlistedinthisleaflet,pleasetell yourdoctororpharmacist.
5 How to store Amoxil
Keepoutofthereachandsightofchildren. DonotuseAmoxilaftertheexpirydatewhichis statedonthecarton.Theexpirydatereferstothe lastdayofthatmonth. Storeintheoriginalpackbelow25C. DonotuseAmoxiliftherearevisiblesignsof deterioration. Medicinesshouldnotbedisposedofvia wastewaterorhouseholdwaste.Askyour pharmacisthowtodisposeofmedicinesnolonger required.Thesemeasureswillhelptoprotectthe environment.
6 Further information
What Amoxil contains
Theactivesubstanceineachcapsuleis250mg or500mgamoxicillin. Theotheringredientsaremagnesiumstearate (E572),erythrosine(E127),indigocarmine(E132), titaniumdioxide(E171),yellowironoxide(E172) andgelatin.
What Amoxil looks like and contents of the pack
AmoxilCapsulesaremaroonandgoldcapsules overprintedGSLEXforthe250mgcapsuleor GSJVLforthe500mgcapsule.Theyarepackaged inblisterpacks,enclosedinacarton.Eachpack contains21capsules.
Marketing Authorisation Holder and Manufacturer
MarketingAuthorisationHolder: GlaxoSmithKlineUK,StockleyParkWest, Uxbridge,MiddlesexUB111BT Manufacturer: GlaxoWelcomeProduction,Terras2, ZoneIndustrielledelaPeyenniere, 53100Mayenne,France
Other formats
TolistentoorrequestacopyofthisleafletinBraille, largeprintoraudiopleasecall,freeofcharge:
If any of the above happen stop taking the medicine and see your doctor straight away. Sometimes you may get less severe skin reactions such as:
amildlyitchyrash(round,pink-redpatches), hive-likeswollenareasonforearms,legs,palms, handsorfeet.Thisisuncommon(affectslessthan 1in100people).
08001985000(UKOnly)
Pleasebereadytogivethefollowinginformation:
Product name
Amoxil Capsules 250 mg Amoxil Capsules 500 mg
If you have any of these talk to your doctor as Amoxil will need to be stopped.
Theotherpossiblesideeffectsare: Common(affectslessthan1in10people) skinrash feelingsick(nausea) diarrhoea. Uncommon(affectslessthan1in100people) beingsick(vomiting). Very rare(affectslessthan1in10,000people) thrush(ayeastinfectionofthevagina,mouthor skinfolds),youcangettreatmentforthrushfrom yourdoctororpharmacist
Referencenumber 00038/0103 ThisisaserviceprovidedbytheRoyalNational InstituteofBlindPeople. Leafletdate:September2010 Amoxilandthemaroonandgoldcapsules areregisteredtrademarksoftheGlaxoSmithKline groupofcompanies 2010GlaxoSmithKlinegroupofcompanies
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

