AMOXICILLIN CAPSULES BP 250MG

Active substance: AMOXICILLIN TRIHYDRATE

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Transcript
required to achieve the recommended dose.
NOTE:
Always follow your doctor's advice about when and how to
take your medicine and always read the label. It is
important that you complete the full course of antibiotics.

1. What Amoxicillin Capsules are and what are they
used for?
Amoxicillin is one of the penicillin group of antibiotics. It is
a broad spectrum antibiotic.
It is used to treat infections in different parts of the body
caused by bacteria that are susceptible to amoxicillin. It is
mostly used to treat respiratory, middle ear infections and
urinary tract infections. It is also used to stop infections
when you have a tooth removed or other surgery.
Amoxicillin may also be used in combination with other
medicines to treat stomach ulcers.
2. What you need to know before you take Amoxicillin
Capsules
Do not take Amoxicillin Capsules if you
• are allergic (hypersensitive) to amoxicillin trihydrate,
penicillin or to any of the ingredients of the capsules
listed in Section 6.
• have ever had an allergic reaction to any antibiotic.
This can include a skin rash or swelling of the face
or neck.
Warnings and precautions
Talk to your doctor or pharmacist before taking Amoxicillin
Capsules.
Take special care and consult your doctor before
taking Amoxicillin Capsules if you:
• suffer from kidney problems
• are suffering from lymphatic leukaemia or HIV
infection. You may be more at risk of developing a
rash.
• have glandular fever
• are not passing water regularly
If you are not sure if any of the above apply to you, talk to
your doctor or pharmacist before taking Amoxicillin.
Having urine or blood tests
If you are having tests on your water (urine glucose tests)
or blood tests for liver function, let the doctor or nurse
know that you are on Amoxicillin. This is because
Amoxicillin can affect the results of these tests.
Other Medicines and Amoxicillin Capsules:
Tell your doctor or pharmacist if you are taking, have
recently taken or might take any other medicines,
including products you do not need a prescription for as
they may interfere with this product.
• If you are taking allopurinol (used for gout) with
amoxicillin, it may be more likely that you'll have an
allergic skin reaction.
• If you are taking probenecid (used to treat gout, a form
of arthritis), your doctor may decide to adjust your
dose of amoxicillin.
• If medicines to help stop blood clots (anticoagulants
such as warfarin or acenocoumarol) are taken with
amoxicillin, then extra blood tests may be needed.
• If the product is given at the same time as the oral
contraceptive the contraceptive may not be as
effective and extra precautions should be taken e.g.
use of condoms.

Pregnancy, breast feeding and fertility
If you are pregnant or breast feeding, think you may be
pregnant or are planning to have a baby, ask your doctor
or pharmacist for advice before taking any medicine.
Driving and using machines
Amoxicillin has not been shown to have any effect on
ability to drive and use machines.
Amoxicillin Capsules contain methyl paraben and
propyl paraben
Methyl Paraben and Propyl Paraben may cause hives.
There may be a delayed reaction such as contact
dermatitis. There is rarely an immediate reaction with
hives and bronchospasm.

If you forget to take Amoxicillin Capsules at the correct
time, take it as soon as you remember and carry on as
before. If it is almost time for your next dose, skip the
missed dose and continue as usual. Do not take a double
dose to make up for a forgotten tablet.
If you have any further questions on the use of this
medicine, ask your doctor or pharmacist.
4. Possible side effects:
Like all medicines, this medicine can cause side effects,
although not everybody gets them. The following side
effects may happen with this medicine.

3. How to take Amoxicillin Capsules
Always take Amoxicillin Capsules exactly as your doctor
has told you. Check with your doctor or pharmacist if you
are not sure.
The maximum recommended dose is 6 g per day
given as 2 x 3 g doses.
The usual dose is:
Adults, elderly patients and children weighing over
40 kg
Standard dose: 1 x 250 mg capsule 3 times a day
Severe infections: 1 x 500 mg capsule 3 times a day
Severe or recurrent chest infection: 3 g (6 x 500 mg
capsules) twice a day
Urinary tract (water) infection: 2 x 3 g doses (6 x 500 mg
capsules) with 10 to 12 hours between each dose
Dental abscess (infection under the gums and teeth):
2 x 3 g doses (6 x 500 mg capsules) with 8 hours between
each dose
Gonorrhoea (a sexually transmitted infection): 1 x 3 g
dose (6 x 500 mg capsules)
Stomach ulcers: 1 x 750 mg dose (3 x 250 mg capsules
or 1 x 500 mg capsule and 1 x 250 mg capsule) or 1 x 1 g
dose (2 x 500 mg capsules) twice a day for 7 days with
other antibiotics
To stop infection during surgery
• The dose will vary according to the type of surgery.
Other medicines may also be given at the same time.
• Your doctor, pharmacist or nurse can give you more
details.
Your doctor will decide on the appropriate dose to suit the
severity and type of infection you have.
Children weighing <40kg.
The daily dosage for children is 40-90mg/kg/day in two to
three divided doses (not exceeding 3g/day) depending on
the indication, severity of the disease and the
susceptibility of the pathogen.
Severe or recurrent ear infections particularly
inflammation of the middle ear (acute otitis media):
750 mg twice daily for two days may be prescribed as an
alternative course of treatment in children aged 3 to 10
years.
Kidney problems
The dose may be reduced in those with kidney problems.
Amoxicillin Mixture BP 125mg/5ml or 250mg/5ml may be

By reporting side effects you can help provide more
information on the safety of this medicine.
5. How to store Amoxicillin Capsules

Stop taking amoxicillin and see a doctor straight
away, if you notice any of the following serious side
effects – you may need urgent medical treatment:

Keep this medicine out of reach and sight of children.
Do not use this medicine after the expiry date shown on
the label.

The following are very rare (affects less than 1 in 10,000
people)

Store in a dry place at or below 25°C.

• allergic reactions, the signs may include: skin itching
or rash, swelling of the face, lips, tongue, body or
breathing difficulties. These can be serious and
occasionally deaths have occurred
• rash or pinpoint flat red round spots under the skin
surface or bruising of the skin. This is due to
inflammation of blood vessel walls due to an allergic
reaction. It can be associated with joint pain (arthritis)
and kidney problems
• a delayed allergic reaction can occur usually 7 to 12
days after having amoxicillin, some signs include:
rashes, fever, joint pains and enlargement of the
lymph nodes especially under the arms
• a skin reaction known as 'erythema multiforme' where
you may develop: itchy reddish purple patches on the
skin especially on the palms of the hands or soles of
the feet, 'hive-like' raised swollen areas on the skin,
tender areas on the surfaces of the mouth, eyes and
private parts. You may have a fever and be very tired
• other severe skin reactions can include: changes in
skin colour, bumps under the skin, blistering,
pustules, peeling, redness, pain, itching, scaling.
These may be associated with fever, headaches and
body aches
• high temperature (fever), chills, a sore throat or other
signs of an infection, or if you bruise easily. These
may be signs of a problem with your blood cells
• inflammation of the large bowel (colon) with diarrhoea
sometimes containing blood, pain and fever
• liver disease characterized by nausea, vomiting, loss
of appetite, feeling generally unwell, fever, itching,
yellowing of the skin and eyes, light coloured bowel
motions, dark coloured urine, rise in liver enzymes
(AST, ALT) [hepatitis, cholestatic jaundice]
If any of the above happens stop taking the medicine
and see your doctor straight away.
Sometimes you may get less severe skin reactions
such as:
• a mildly itchy rash (round, pink-red patches), 'hivelike' swollen areas on forearms, legs, palms, hands or
feet. This is uncommon (affects less than 1 in 100
people).
If you have any of these talk to your doctor as
amoxicillin will need to be stopped.

Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help
to protect the environment.
6. Contents of the pack and other information:
What Amoxicillin Capsules contain
These capsules are called Amoxicillin Capsules BP
250mg or 500mg.
Each capsule contains the active ingredient Amoxicillin
Trihydrate BP equivalent to 250mg or 500mg of
Amoxicillin.
Each capsule also contains Magnesium Stearate (E572),
Colloidal Anhydrous Silica, Titanium Dioxide (E171), Iron
Oxides (E172), Erythrosine (E127), Indigo Carmine
(E132), Methyl Paraben (E218), Propyl Paraben (E216),
Sodium Lauryl Sulphate and gelatin. The ink is composed
of Shellac, Isopropyl Alcohol, Purified Water, N-Butyl
alcohol, Black iron Oxide (E172), Propylene Glycol,
Strong Ammonia Solution, Potassium Hydroxide and
Dehydrated Alcohol.
What Amoxicillin Capsules look like and contents of
the pack
Amoxicillin Capsules BP 250mg are hard gelatine size 1
buff/scarlet capsules identity marked RAMX250
Amoxicillin Capsules BP 500mg are hard gelatine size 0
elongated buff/scarlet capsules identity marked
RAMX500
Amoxicillin Capsules BP 250mg are available in packs of
15, 20, 21, 50, 100, 500 and 1000 capsules and the
Amoxicillin Capsules BP 500mg are available in packs of
15, 20, 21,100, 500 and 1000 capsules. Both products are
also available in blister strips of 15 and 21 capsules.
Marketing Authorisation Holder and Manufacturer
The product licence is held by the manufacturers,
Ranbaxy Ireland Ltd., Spafield, Cork Road, Cashel, Co.
Tipperary, Ireland.
Date of Revision: October 2014

FONT SIZE : 8PT

What is in this leaflet:
1. What Amoxicillin Capsules are and what are they used for
2. What you need to know before you take Amoxicillin Capsules
3. How to take Amoxicillin Capsules
4. Possible side effects
5. How to store Amoxicillin Capsules
6. Contents of the pack and other information.

How long should you take Amoxicillin for?
• Keep taking Amoxicillin until the treatment is finished,
even if you feel better. You need every dose to help
fight the infection. If some bacteria survive they can
cause the infection to come back. Treatment should
be continued for 2 to 3 days after the symptoms have
gone.
• Do not take Amoxicillin for more than 2 weeks. If you
still feel unwell you should go back to see the doctor.
Thrush (a yeast infection of moist areas of the body) may
develop if Amoxicillin is used for a long time. If this occurs
and you have been taking Amoxicillin for longer than
recommended, tell your doctor.
If you take more Amoxicillin Capsules than you
should contact your doctor or pharmacist who will
recommend what action you should take. Signs of an
overdose include upset stomach (feeling sick, being sick
or diarrhoea) or crystals in the urine, which may be seen
as cloudy urine, or problems passing urine. Take the
medicine to show the doctor.

5113004

Read all of this leaflet carefully before you start taking this medicine because it contains important
information for you.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their
signs of illness are the same as yours.
• If you get any of the side effects, talk to your doctor or pharmacist. This includes any possible side effects
not listed in this section. See section 4.

The other possible side effects are:
Common (affects less than 1 in 10 people)
• skin rash
• feeling sick (nausea)
• diarrhoea
Uncommon (affects less than 1 in 100 people)
• being sick (vomiting)
Very rare (affects less than 1 in 10,000 people)
• thrush (a yeast infection of the vagina, mouth or skin
folds), you can get treatment for thrush from your
doctor or pharmacist
• kidney problems
• fits (convulsions), seen in patients on high doses or
with kidney problems
• dizziness
• hyperactivity
• crystals in the urine, which may be seen as cloudy
urine, or difficulty or discomfort in passing urine. Make
sure you drink plenty of fluids to reduce the chance of
these symptoms
• teeth may appear stained, usually returning to normal
with brushing (this has been reported in children)
• the tongue may change to yellow, brown or black and
it may have a hairy appearance
• an excessive breakdown of red blood cells causing a
form of anaemia. Signs include: tiredness,
headaches, shortness of breath, dizziness, looking
pale and yellowing of the skin and the whites of the
eyes
• the blood may take longer to clot than it normally
would. You may notice this if you have a nosebleed or
cut yourself.
Reporting of side effects
If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects not
listed in this leaflet. You can also report side effects
d i r e c t l y v i a t h e Ye l l o w C a r d S c h e m e a t :
www.mhra.gov.uk/yellowcard.

5113005

Amoxicillin Mixture BP 125mg/5ml or 250mg/5ml may be
required to achieve the recommended dose.
NOTE:
Always follow your doctor's advice about when and how to
take your medicine and always read the label. It is
important that you complete the full course of antibiotics.

1. What Amoxicillin Capsules are and what are they
used for?
Amoxicillin is one of the penicillin group of antibiotics. It is
a broad spectrum antibiotic.
It is used to treat infections in different parts of the body
caused by bacteria that are susceptible to amoxicillin. It is
mostly used to treat respiratory, middle ear infections and
urinary tract infections. It is also used to stop infections
when you have a tooth removed or other surgery.
Amoxicillin may also be used in combination with other
medicines to treat stomach ulcers.
2. What you need to know before you take Amoxicillin
Capsules

Pregnancy, breast feeding and fertility
If you are pregnant or breast feeding, think you may be
pregnant or are planning to have a baby, ask your doctor
or pharmacist for advice before taking any medicine.
Driving and using machines
Amoxicillin has not been shown to have any effect on
ability to drive and use machines.
Amoxicillin Capsules contain methyl paraben and
propyl paraben
Methyl Paraben and Propyl Paraben may cause hives.
There may be a delayed reaction such as contact
dermatitis. There is rarely an immediate reaction with
hives and bronchospasm.
3. How to take Amoxicillin Capsules

Do not take Amoxicillin Capsules if you
• are allergic (hypersensitive) to amoxicillin trihydrate,
penicillin or to any of the ingredients of the capsules
listed in Section 6.
• have ever had an allergic reaction to any antibiotic.
This can include a skin rash or swelling of the face
or neck.
Warnings and precautions
Talk to your doctor or pharmacist before taking Amoxicillin
Capsules.
Take special care and consult your doctor before
taking Amoxicillin Capsules if you:
• suffer from kidney problems
• are suffering from lymphatic leukaemia or HIV
infection. You may be more at risk of developing a
rash.
• have glandular fever
• are not passing water regularly
If you are not sure if any of the above apply to you, talk to
your doctor or pharmacist before taking Amoxicillin.
Having urine or blood tests
If you are having tests on your water (urine glucose tests)
or blood tests for liver function, let the doctor or nurse
know that you are on Amoxicillin. This is because
Amoxicillin can affect the results of these tests.
Other Medicines and Amoxicillin Capsules:
Tell your doctor or pharmacist if you are taking, have
recently taken or might take any other medicines,
including products you do not need a prescription for as
they may interfere with this product.
• If you are taking allopurinol (used for gout) with
amoxicillin, it may be more likely that you'll have an
allergic skin reaction.
• If you are taking probenecid (used to treat gout, a form
of arthritis), your doctor may decide to adjust your
dose of amoxicillin.
• If medicines to help stop blood clots (anticoagulants
such as warfarin or acenocoumarol) are taken with
amoxicillin, then extra blood tests may be needed.
• If the product is given at the same time as the oral
contraceptive the contraceptive may not be as
effective and extra precautions should be taken e.g.
use of condoms.

Always take Amoxicillin Capsules exactly as your doctor
has told you. Check with your doctor or pharmacist if you
are not sure.
The maximum recommended dose is 6 g per day
given as 2 x 3 g doses.
The usual dose is:
Adults, elderly patients and children weighing over
40 kg
Standard dose: 1 x 250 mg capsule 3 times a day
Severe infections: 1 x 500 mg capsule 3 times a day
Severe or recurrent chest infection: 3 g (6 x 500 mg
capsules) twice a day
Urinary tract (water) infection: 2 x 3 g doses (6 x 500 mg
capsules) with 10 to 12 hours between each dose
Dental abscess (infection under the gums and teeth):
2 x 3 g doses (6 x 500 mg capsules) with 8 hours between
each dose
Gonorrhoea (a sexually transmitted infection): 1 x 3 g
dose (6 x 500 mg capsules)
Stomach ulcers: 1 x 750 mg dose (3 x 250 mg capsules
or 1 x 500 mg capsule and 1 x 250 mg capsule) or 1 x 1 g
dose (2 x 500 mg capsules) twice a day for 7 days with
other antibiotics
To stop infection during surgery
• The dose will vary according to the type of surgery.
Other medicines may also be given at the same time.
• Your doctor, pharmacist or nurse can give you more
details.
Your doctor will decide on the appropriate dose to suit the
severity and type of infection you have.
Children weighing <40kg.
The daily dosage for children is 40-90mg/kg/day in two to
three divided doses (not exceeding 3g/day) depending on
the indication, severity of the disease and the
susceptibility of the pathogen.
Severe or recurrent ear infections particularly
inflammation of the middle ear (acute otitis media):
750 mg twice daily for two days may be prescribed as an
alternative course of treatment in children aged 3 to 10
years.
Kidney problems
The dose may be reduced in those with kidney problems.

If you forget to take Amoxicillin Capsules at the correct
time, take it as soon as you remember and carry on as
before. If it is almost time for your next dose, skip the
missed dose and continue as usual. Do not take a double
dose to make up for a forgotten tablet.
If you have any further questions on the use of this
medicine, ask your doctor or pharmacist.
4. Possible side effects:

By reporting side effects you can help provide more
information on the safety of this medicine.

Like all medicines, this medicine can cause side effects,
although not everybody gets them. The following side
effects may happen with this medicine.

5. How to store Amoxicillin Capsules

Stop taking amoxicillin and see a doctor straight
away, if you notice any of the following serious side
effects – you may need urgent medical treatment:

Keep this medicine out of reach and sight of children.
Do not use this medicine after the expiry date shown on
the label.

The following are very rare (affects less than 1 in 10,000
people)

Store in a dry place at or below 25°C.

• allergic reactions, the signs may include: skin itching
or rash, swelling of the face, lips, tongue, body or
breathing difficulties. These can be serious and
occasionally deaths have occurred
• rash or pinpoint flat red round spots under the skin
surface or bruising of the skin. This is due to
inflammation of blood vessel walls due to an allergic
reaction. It can be associated with joint pain (arthritis)
and kidney problems
• a delayed allergic reaction can occur usually 7 to 12
days after having amoxicillin, some signs include:
rashes, fever, joint pains and enlargement of the
lymph nodes especially under the arms
• a skin reaction known as 'erythema multiforme' where
you may develop: itchy reddish purple patches on the
skin especially on the palms of the hands or soles of
the feet, 'hive-like' raised swollen areas on the skin,
tender areas on the surfaces of the mouth, eyes and
private parts. You may have a fever and be very tired
• other severe skin reactions can include: changes in
skin colour, bumps under the skin, blistering,
pustules, peeling, redness, pain, itching, scaling.
These may be associated with fever, headaches and
body aches
• high temperature (fever), chills, a sore throat or other
signs of an infection, or if you bruise easily. These
may be signs of a problem with your blood cells
• inflammation of the large bowel (colon) with diarrhoea
sometimes containing blood, pain and fever
• liver disease characterized by nausea, vomiting, loss
of appetite, feeling generally unwell, fever, itching,
yellowing of the skin and eyes, light coloured bowel
motions, dark coloured urine, rise in liver enzymes
(AST, ALT) [hepatitis, cholestatic jaundice]
If any of the above happens stop taking the medicine
and see your doctor straight away.
Sometimes you may get less severe skin reactions
such as:
• a mildly itchy rash (round, pink-red patches), 'hivelike' swollen areas on forearms, legs, palms, hands or
feet. This is uncommon (affects less than 1 in 100
people).
If you have any of these talk to your doctor as
amoxicillin will need to be stopped.

Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help
to protect the environment.
6. Contents of the pack and other information:
What Amoxicillin Capsules contain
These capsules are called Amoxicillin Capsules BP
250mg or 500mg.
Each capsule contains the active ingredient Amoxicillin
Trihydrate BP equivalent to 250mg or 500mg of
Amoxicillin.
Each capsule also contains Magnesium Stearate (E572),
Colloidal Anhydrous Silica, Titanium Dioxide (E171), Iron
Oxides (E172), Erythrosine (E127), Indigo Carmine
(E132), Methyl Paraben (E218), Propyl Paraben (E216),
Sodium Lauryl Sulphate and gelatin. The ink is composed
of Shellac, Isopropyl Alcohol, Purified Water, N-Butyl
alcohol, Black iron Oxide (E172), Propylene Glycol,
Strong Ammonia Solution, Potassium Hydroxide and
Dehydrated Alcohol.
What Amoxicillin Capsules look like and contents of
the pack
Amoxicillin Capsules BP 250mg are hard gelatine size 1
buff/scarlet capsules identity marked RAMX250
Amoxicillin Capsules BP 500mg are hard gelatine size 0
elongated buff/scarlet capsules identity marked
RAMX500
Amoxicillin Capsules BP 250mg are available in packs of
15, 20, 21, 50, 100, 500 and 1000 capsules and the
Amoxicillin Capsules BP 500mg are available in packs of
15, 20, 21,100, 500 and 1000 capsules. Both products are
also available in blister strips of 15 and 21 capsules.
Marketing Authorisation Holder and Manufacturer
The product licence is held by the manufacturers,
Ranbaxy Ireland Ltd., Spafield, Cork Road, Cashel, Co.
Tipperary, Ireland.
Date of Revision: October 2014

FONT SIZE : 8PT

What is in this leaflet:
1. What Amoxicillin Capsules are and what are they used for
2. What you need to know before you take Amoxicillin Capsules
3. How to take Amoxicillin Capsules
4. Possible side effects
5. How to store Amoxicillin Capsules
6. Contents of the pack and other information.

How long should you take Amoxicillin for?
• Keep taking Amoxicillin until the treatment is finished,
even if you feel better. You need every dose to help
fight the infection. If some bacteria survive they can
cause the infection to come back. Treatment should
be continued for 2 to 3 days after the symptoms have
gone.
• Do not take Amoxicillin for more than 2 weeks. If you
still feel unwell you should go back to see the doctor.
Thrush (a yeast infection of moist areas of the body) may
develop if Amoxicillin is used for a long time. If this occurs
and you have been taking Amoxicillin for longer than
recommended, tell your doctor.
If you take more Amoxicillin Capsules than you
should contact your doctor or pharmacist who will
recommend what action you should take. Signs of an
overdose include upset stomach (feeling sick, being sick
or diarrhoea) or crystals in the urine, which may be seen
as cloudy urine, or problems passing urine. Take the
medicine to show the doctor.

5113005

Read all of this leaflet carefully before you start taking this medicine because it contains important
information for you.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their
signs of illness are the same as yours.
• If you get any of the side effects, talk to your doctor or pharmacist. This includes any possible side effects
not listed in this section. See section 4.

The other possible side effects are:
Common (affects less than 1 in 10 people)
• skin rash
• feeling sick (nausea)
• diarrhoea
Uncommon (affects less than 1 in 100 people)
• being sick (vomiting)
Very rare (affects less than 1 in 10,000 people)
• thrush (a yeast infection of the vagina, mouth or skin
folds), you can get treatment for thrush from your
doctor or pharmacist
• kidney problems
• fits (convulsions), seen in patients on high doses or
with kidney problems
• dizziness
• hyperactivity
• crystals in the urine, which may be seen as cloudy
urine, or difficulty or discomfort in passing urine. Make
sure you drink plenty of fluids to reduce the chance of
these symptoms
• teeth may appear stained, usually returning to normal
with brushing (this has been reported in children)
• the tongue may change to yellow, brown or black and
it may have a hairy appearance
• an excessive breakdown of red blood cells causing a
form of anaemia. Signs include: tiredness,
headaches, shortness of breath, dizziness, looking
pale and yellowing of the skin and the whites of the
eyes
• the blood may take longer to clot than it normally
would. You may notice this if you have a nosebleed or
cut yourself.
Reporting of side effects
If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects not
listed in this leaflet. You can also report side effects
d i r e c t l y v i a t h e Ye l l o w C a r d S c h e m e a t :
www.mhra.gov.uk/yellowcard.

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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