ZyrTEC Liquid Gels Side Effects

Generic Name: cetirizine, cetirizine hydrochloride

Please note - some side effects for ZyrTEC Liquid Gels may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Applies to: oral capsule; oral syrup; oral tablet; oral tablet, chewable; oral tablet, dispersible

Nervous system

Nervous system side effects have included headache (16%), fatigue (5.6%), and somnolence (5% to 20%). Somnolence tends to be dose-related and generally occurs more frequently with doses higher than 10 mg per day. Other nervous system side effects include dizziness (1.8%), insomnia (1.5%), and nervousness (1.1%). Post marketing reports have included aggression reaction and convulsions.

Cetirizine appears to be more sedating than loratadine.

Gastrointestinal

Gastrointestinal side effects have included dry mouth (5.7%) and nausea or vomiting (2.2%). Pharyngitis, dyspepsia, and increased appetite have occasionally been reported.

Hepatic

Hepatic side effects have included rare liver function test abnormalities which resolved spontaneously following discontinuation of cetirizine therapy. At least one case of recurrent acute hepatitis has also been associated with cetirizine use.

Respiratory

Respiratory side effects have included relatively rare reports of wheezing, coughing, bronchitis, sinusitis, and asthma.

Dermatologic

Dermatologic side effects have included reports of maculopapular and urticarial eruptions. Fixed drug eruptions have also been associated with cetirizine.

General

General side effects have included epistaxis (1.1%) and accidental injury (1.1%).

Hypersensitivity

Hypersensitivity side effects have included a case report of an anaphylactic reaction.

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