Zema Pak 10-Day Side Effects
Generic Name: dexamethasone, dexamethasone sodium phosphate
Please note - some side effects for Zema Pak 10-Day may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Side Effects by Body System - for Healthcare Professionals
Applies to: compounding powder; inhalation aerosol with adapter; injectable solution; injectable suspension; intravenous solution; oral concentrate; oral liquid; oral tablet
Cardiovascular side effects have included bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, myocardial rupture following recent myocardial infarction, edema, pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis and vasculitis.
Musculoskeletal side effects have included muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, aseptic necrosis of femoral and humoral heads, pathologic fracture of long bones, and tendon rupture.
Gastrointestinal side effects have included peptic ulcer with potential perforation and hemorrhage, perforation of small and large bowel, pancreatitis, abdominal distention, nausea, increased appetite, and ulcerative esophagitis.
Endocrine side effects have included development of cushingoid state, suppression of growth in children, and secondary adrenocortical and pituitary unresponsiveness.
Nervous system side effects have included convulsions, increased intracranial pressure with papilledema, vertigo, myalgia, arthralgia, malaise, headache, hiccups, and psychic disturbances.
Metabolic side effects have included negative nitrogen balance due to protein catabolism, decreased carbohydrate and glucose tolerance, weight gain, hirsutism, hypokalemic alkalosis, and increased requirements for insulin or oral hypoglycemic agents in diabetics.
Ocular side effects have included posterior subcapsular cataracts, increased intraocular pressure, glaucoma, and exophthalmos.
Dermatologic side effects have included impaired wound healing, thin fragile skin, petechiae and ecchymoses, dry scaly skin, erythema, acne, thinning scalp hair, urticaria, increased sweating, rash, striae, allergic dermatitis, urticaria, angioneurotic edema, and suppression of skin test reactions.
Psychiatric side effects have included euphoria, insomnia, mood swings, personality changes, severe depression, and psychotic manifestations.
Hematologic side effects have included rare reports of thromboembolism.
Genitourinary effects have included increase/decrease in motility and number of spermatozoa in men and menstrual irregularities in women.
Hepatic side effects have included reports of reversible hepatomegaly. Three case reports of children treated with high dose dexamethasone describe the earliest diagnosis of hepatomegaly as early as 8 days from the start of therapy.
Hypersensitivity side effects have included anaphylactoid reactions, anaphylaxis and angioedema.
Renal side effects have included fluid retention, sodium retention, and potassium loss,Top
- Zema Pak 10-Day Concise Consumer Information (Cerner Multum)
- Dexamethasone Professional Patient Advice (Wolters Kluwer)
- Dexamethasone Prescribing Information (FDA)
- Dexamethasone Monograph (AHFS DI)
- Baycadron Prescribing Information (FDA)
- Cortastat injection Concise Consumer Information (Cerner Multum)
- Decadron Prescribing Information (FDA)
- Decadron MedFacts Consumer Leaflet (Wolters Kluwer)
- Decadron Advanced Consumer (Micromedex) - Includes Dosage Information
- DexPak 10 Day TaperPak Prescribing Information (FDA)
- Dexamethasone Sodium Phosphate eent Monograph (AHFS DI)
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