Yohimbe Side Effects

Generic Name: yohimbine

Note: This page contains side effects data for the generic drug yohimbine. It is possible that some of the dosage forms included below may not apply to the brand name Yohimbe.

It is possible that some side effects of Yohimbe may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to yohimbine: oral tablet

If you experience any of the following serious side effects, stop taking yohimbine (the active ingredient contained in Yohimbe) and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  • a very irregular or fast heartbeat; or

  • confusion or unusual behavior.

Other, less serious side effects are more likely to occur. Continue to take yohimbine and talk to your doctor if you experience

  • dizziness;

  • anxiety, irritability, or nervousness;

  • tremor (shaking);

  • headache; or

  • skin flushing.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to yohimbine: compounding powder, oral tablet

Nervous system

Nervous system side effects have included excitation, increased motor activity, tremor, and dizziness.

Cardiovascular

Cardiovascular side effects have included elevation in blood pressure and increase in heart rate.

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting, commonly reported after parenteral administration of yohimbine (the active ingredient contained in Yohimbe)

Psychiatric

Psychiatric side effects have included irritability and generalized anxiety.

General

General side effects have included headache and increase in sweating.

Dermatologic

Dermatologic side effects have included skin flushing reported with oral administration.

Other

A severe case of Raynaud's phenomenon has been reported in a 65-year-old man diagnosed with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia). Painful episodes which affected all toes and fingers and his penis lasted 10 to 15 minutes and were relieved with heat. Symptoms resolved slowly over time upon discontinuation of yohimbine (the active ingredient contained in Yohimbe) Upon rechallenge with yohimbine, the patient developed more severe Raynaud's phenomenon.

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