Xyzal Side Effects

Generic Name: levocetirizine

Note: This page contains side effects data for the generic drug levocetirizine. It is possible that some of the dosage forms included below may not apply to the brand name Xyzal.

It is possible that some side effects of Xyzal may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to levocetirizine: oral solution, oral tablet

As well as its needed effects, levocetirizine (the active ingredient contained in Xyzal) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking levocetirizine, check with your doctor immediately:

Less common
  • Bloody nose
  • fever
Incidence not known
  • Anxiety
  • attack, assault, or force
  • blurred or loss of vision
  • cough
  • dark urine
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficult or labored breathing
  • difficulty in passing urine (dribbling)
  • difficulty with swallowing
  • disturbed color perception
  • dizziness
  • double vision
  • dry mouth
  • fast, irregular, pounding, or racing heartbeat or pulse
  • general tiredness and weakness
  • halos around lights
  • hives or welts
  • hyperventilation
  • irritability
  • itching skin
  • joint or muscle pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • light-colored stools
  • nausea and vomiting
  • nervousness
  • night blindness
  • overbright appearance of lights
  • painful urination
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • restlessness
  • seizures
  • shaking
  • skin rash
  • tightness in the chest
  • trouble with sleeping
  • tunnel vision
  • upper right abdominal or stomach pain
  • yellow eyes and skin

Some levocetirizine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Headache
  • muscle aches
  • sleepiness or unusual drowsiness
  • sore throat
  • stuffy or runny nose
Less common
  • Body aches or pain
  • congestion
  • diarrhea
  • dryness or soreness of the throat
  • earache
  • hoarseness
  • redness or swelling in the ear
  • tender, swollen glands in the neck
  • voice changes

For Healthcare Professionals

Applies to levocetirizine: oral solution, oral tablet

Cardiovascular

Postmarketing reports: Palpitations, tachycardia[Ref]

Dermatologic

Postmarketing reports: Fixed drug eruption, pruritus, rash, urticaria[Ref]

Gastrointestinal

Very common (10% or more): Dry mouth
Common (1% to 10%): Diarrhea, vomiting, constipation
Postmarketing reports: Nausea[Ref]

Hypersensitivity

Frequency not reported: Anaphylaxis
Postmarketing reports: Angioedema[Ref]

Nervous system

Very common (10% or more): Somnolence, fatigue
Common (1% to 10%): Asthenia
Postmarketing reports: Convulsions, paresthesia, dizziness, tremors, vertigo, movement disorders (dystonia and oculogyric crisis), tic, myoclonus, extrapyramidal symptoms[Ref]

Hepatic

Uncommon (0.1% to 1%): Elevations of blood bilirubin and transaminases
Postmarketing reports: Hepatitis[Ref]

Ocular

Postmarketing reports: Visual disturbances, blurred vision[Ref]

Respiratory

Very common (10% or more): Nasopharyngitis, pharyngitis,
Common (1% to 10%): Cough, epistaxis
Postmarketing reports: Dyspnea[Ref]

Psychiatric

Postmarketing reports: Aggression, agitation, hallucinations, suicidal ideation, dysgeusia, insomnia

Musculoskeletal

Postmarketing reports: Myalgia

Genitourinary

Postmarketing reports: Urinary retention, dysuria

General

The most common adverse reactions were: somnolence, nasopharyngitis, fatigue, dry mouth and pharyngitis (in 12 years and older); pyrexia, somnolence, cough and epistaxis (in 6 to 12 year olds); pyrexia, diarrhea, vomiting, and otitis media (in 1 to 5 year olds); diarrhea and constipation (in 6 to 11 months of age)

Other

Common (1% to 10%): Pyrexia
Uncommon (0.1% to 1%): Otitis Media
Postmarketing reports: Increased appetite, edema

References

1. "Product Information. Xyzal (levocetirizine)." UCB Pharma Inc, Smyrna, GA.

2. Layton D, Wilton L, Boshier A, Cornelius V, Harris S, Shakir SA "Comparison of the risk of drowsiness and sedation between levocetirizine and desloratadine: a prescription-event monitoring study in England." Drug Saf 29 (2006): 897-909

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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