Xeomin Side Effects
Generic Name: incobotulinumtoxinA
Note: This document contains side effect information about incobotulinumtoxinA. Some of the dosage forms listed on this page may not apply to the brand name Xeomin.
Some side effects of Xeomin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to incobotulinumtoxinA: intramuscular powder for solution
Along with its needed effects, incobotulinumtoxinA (the active ingredient contained in Xeomin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking incobotulinumtoxinA:More common—for cervical dystonia
- Difficulty with swallowing
- muscle or bone pain
- muscle weakness
- pain in the neck
- Dry eyes
- Itching, pain, redness, or swelling at the injection site
- pain in the face
- swelling of the eyelids
- Changes in patterns and rhythms of speech
- fast heartbeat
- joint pain, stiffness, or swelling
- muscle spasm
- pain at the injection site
- redness of the skin
- shortness of breath
- slurred speech
- swelling of the eyes or eyelids
- swelling of the face, lips, hands, or feet
- tightness in the chest
- trouble with speaking
- troubled breathing or swallowing
Some side effects of incobotulinumtoxinA may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common—for cervical dystonia
- lower back or side pain
- painful or difficult urination
- Blurred vision
- drooping upper eyelids
- dry mouth
- Difficult or labored breathing
- muscle aches
- sore throat
- stuffy or runny nose
- unusual tiredness or weakness
- Drooping of the eyelids
- increased blinking
- twitching of the eyelids
- Difficulty with moving
- joint pain
- muscle aching or cramping
- muscle pains or stiffness
- painful blisters on the trunk of the body
- swollen joints
For Healthcare Professionals
Applies to incobotulinumtoxinA: intramuscular powder for injection
Musculoskeletal side effects have included neck pain (7% to 15%), muscular weakness (7% to 11%), musculoskeletal pain (4% to 7%), and muscle spasm.
Gastrointestinal side effects have included dysphagia (13%), dry mouth (16%), diarrhea (8%), and nausea.
Nervous system side effects have included headache (7%).
Local side effects have included injection site pain (9%), injection site reaction, allergic dermatitis, localized allergic reactions like swelling, edema, erythema, pruritus or rash, and herpes zoster.
Ocular side effects have included eyelid ptosis (19%), dry eye (16%), visual impairment (12%), eye swelling, and eyelid edema.
Respiratory side effects have included nasopharyngitis (5%), respiratory tract infection (5%), and dyspnea (5%).
Immunologic side effects have included infections and infestations (13% to 14%). Postmarketing reports have included flu-like symptoms.
More about Xeomin (incobotulinumtoxinA)
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