Vitamin D3 Side Effects
Generic Name: cholecalciferol
Note: This page contains side effects data for the generic drug cholecalciferol. It is possible that some of the dosage forms included below may not apply to the brand name Vitamin D3.
For the Consumer
Applies to cholecalciferol: oral capsule, oral capsule liquid filled, oral solution, oral tablet, oral tablet chewable, oral wafer
As well as its needed effects, cholecalciferol (the active ingredient contained in Vitamin D3) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking cholecalciferol, check with your doctor immediately:Incidence not known:
- difficulty swallowing
- fast heartbeat
- hives or itching
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- skin rash
- tightness in the chest
- unusual tiredness or weakness
For Healthcare Professionals
Applies to cholecalciferol: compounding crystal, oral capsule, oral liquid, oral solution, oral tablet, oral tablet chewable, oral tablet disintegrating, oral wafer
Early signs and symptoms of hypercalcemia include headache, anorexia, nausea, vomiting, metallic taste, constipation, abdominal cramps, dry mouth, weakness, fatigue, muscle and bone pain, ataxia, tinnitus, and vertigo. Later hypercalcemia may result in pruritus, mental confusion, coma, hypertension, cardiac arrhythmias, seizures, metastatic calcification, and renal insufficiency manifested by polyuria, nocturia, polydipsia, and proteinuria.[Ref]
Metabolic side effects have included hypercalcemia.[Ref]
1. Miller SM "New perspectives on vitamin D." Am J Med Technol 49 (1983): 27-37
2. Araugo OE, Flowers FP, Brown K "Vitamin D therapy in psoriasis." DICP 25 (1991): 835-9
3. Sarar P, Kochanek PM "Vitamin D intoxication associated with an over-the-counter supplement." N Engl J Med 345 (2001): 66-7
It is possible that some side effects of Vitamin D3 may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
More about Vitamin D3 (cholecalciferol)
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