Umeclidinium Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 20, 2023.

Applies to umeclidinium: inhalation powder.

Serious side effects of Umeclidinium

Along with its needed effects, umeclidinium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking umeclidinium:

Less common

• Bladder pain
• bloody or cloudy urine
• body aches or pain
• chest pain
• chills
• cough
• difficult, burning, or painful urination
• difficulty with breathing
• dryness or soreness of the throat
• ear congestion
• fast, pounding, or irregular heartbeat or pulse
• fever
• frequent urge to urinate
• hoarseness
• loss of voice
• lower back or side pain
• sneezing
• sore throat
• tender, swollen glands in the neck
• tightness in the chest
• trouble in swallowing
• unusual tiredness or weakness
• voice changes

Rare

• Dizziness
• fainting

Incidence not known

• Blindness
• blurred vision
• decreased urination
• difficulty in passing urine (dribbling)
• eye pain or discomfort
• hives, itching, skin rash
• hoarseness
• irritation
• joint pain, stiffness, or swelling
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
• nausea
• redness of the skin
• swelling of the eyelids, face, lips, hands, or feet
• tearing
• tightness in the chest
• troubled swallowing
• vomiting

Other side effects of Umeclidinium

Some side effects of umeclidinium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Back, neck, arm, or leg pain
• belching
• bruise
• depression
• diarrhea
• difficulty in moving
• dizziness or lightheadedness
• feeling of constant movement of self or surroundings
• heartburn
• indigestion
• muscle cramps or stiffness
• sensation of spinning
• stomach discomfort, upset, or pain toothache
• upper abdominal or stomach pain

For Healthcare Professionals

Applies to umeclidinium: inhalation powder.

Cardiovascular

Common (1% to 10%): Tachycardia, hypertension, sinus tachycardia (greater than or equal to 1%)

Uncommon (0.1% to 1%): Atrial fibrillation, idioventricular rhythm, supraventricular tachycardia, supraventricular extrasystoles^[Ref]

Dermatologic

Common (1% to 10%): Rash^[Ref]

Gastrointestinal

Common (1% to 10%): Upper abdominal pain, toothache, dyspepsia (greater or equal to 1%), diarrhea (greater or equal to 1%), nausea (greater or equal to 1%)

Uncommon (0.1% to 1%): Constipation, dry mouth^[Ref]

Genitourinary

Common (1% to 10%): Urinary tract infection

Frequency not reported: Worsening of urinary retention^[Ref]

Musculoskeletal

Common (1% to 10%): Arthralgia, myalgia, back pain, neck pain (greater or equal to 1%), pain in extremity (greater or equal to 1%)^[Ref]

Nervous system

Common (1% to 10%): Headache, sinus headache (greater or equal to 1%), dizziness (greater or equal to 1%)

Uncommon (0.1% to 1%): Dysgeusia^[Ref]

Other

Common (1% to 10%): Contusion, vertigo (greater or equal to 1%)^[Ref]

Psychiatric

Common (1% to 10%): Depression (greater or equal to 1%)^[Ref]

Respiratory

Common (1% to 10%): Nasopharyngitis, upper respiratory tract infection, viral respiratory tract infection, cough, sinusitis, pneumonia (greater than or equal to 1%), lower respiratory tract infection (greater than or equal to 1%), rhinitis (greater than or equal to 1%), oropharyngeal pain (greater than or equal to 1%)

Uncommon (0.1% to 1%): Pharyngitis^[Ref]

Ocular

Frequency not reported: Worsening of narrow-angle glaucoma (eye pain or discomfort, blurred vision, visual halos or colored images in association with red eyes from conjunctival congestion and corneal edema)^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer