Trianex Side Effects

Generic Name: triamcinolone topical

Note: This page contains side effects data for the generic drug triamcinolone topical. It is possible that some of the dosage forms included below may not apply to the brand name Trianex.

It is possible that some side effects of Trianex may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to triamcinolone topical: topical application cream, topical application lotion, topical application ointment, topical application spray

As well as its needed effects, triamcinolone topical (the active ingredient contained in Trianex) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking triamcinolone topical, check with your doctor immediately:

Incidence not known
  • Blistering, burning, crusting, dryness, or flaking of the skin
  • irritation
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • redness and scaling around the mouth
  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)

Some triamcinolone topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known
  • Acne or pimples
  • burning and itching of the skin with pinhead-sized red blisters
  • burning, itching, and pain in hairy areas, or pus at the root of the hair
  • increased hair growth on the forehead, back, arms, and legs
  • lightening of normal skin color
  • lightening of treated areas of dark skin
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • softening of the skin

For Healthcare Professionals

Applies to triamcinolone topical: mucous membrane paste, topical cream, topical kit, topical lotion, topical ointment, topical spray

Endocrine

Endocrinologic side effects have been rare. The hypothalamic-pituitary-adrenal axis has been suppressed only rarely. This suppression was more likely when higher potency topical corticosteroids were used over extensive areas and when occlusive dressing were used.

The prolonged use of dental paste has lead to systemic adverse reactions including hyperglycemia and protein catabolism.[Ref]

Local

Skin atrophy may become evident within one to two months of use and is due to the inhibitory effect of corticosteroids on collagen formation. Skin on the face, axillae, and groin appear to be most susceptible to the adverse, long-term effects of topical triamcinolone. Use of high potency topical corticosteroids on these areas should be minimized or avoided.

Topical corticosteroid use may inhibit local immune response rendering the skin more susceptible to infections. Folliculitis has occasionally been reported.

Perioral dermatitis or rosacea-like dermatitis has occurred in patients treated with potent topical corticosteroids who are of seborrheic skin type. This condition may flare temporarily upon discontinuation of topical steroids, prompting patients to continue their use. If topical corticosteroids are discontinued, this flare and the initial dermatitis generally resolves over a few weeks.[Ref]

Local side effects of have commonly included burning, itching, or irritation, especially if applied to denuded skin. Long-term use of topical corticosteroids has resulted in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis is occasionally reported.[Ref]

Gastrointestinal

Gastrointestinal side effects have included peptic ulcer activation after the prolonged use of dental paste.[Ref]

References

1. "Product Information. Kenalog (triamcinolone topical)." Westwood Squibb Pharmaceutical Corporation, Buffalo, NY.

2. May P, Stein EJ, Ryter RJ, Hirsh FS, Michel B, Levy RP "Cushing syndrome from percutaneous absorption of triamcinolone cream." Arch Intern Med 136 (1976): 612-3

3. "Product Information. Aristocort Topical (triamcinolone topical)." Fujisawa, Deerfield, IL.

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