Trecator-SC Side Effects
Generic Name: ethionamide
Note: This page contains side effects data for the generic drug ethionamide. It is possible that some of the dosage forms included below may not apply to the brand name Trecator-SC.
It is possible that some side effects of Trecator-SC may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to ethionamide: oral tablet
As well as its needed effects, ethionamide (the active ingredient contained in Trecator-SC) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking ethionamide, check with your doctor immediately:Less common
- Clumsiness or unsteadiness
- mental depression
- mood or other mental changes
- numbness, tingling, burning, or pain in hands and feet
- yellow eyes or skin
- Blurred vision or loss of vision, with or without eye pain
- changes in menstrual periods
- decreased sexual ability (in males)
- difficulty in concentrating
- dry, puffy skin
- faster heartbeat
- increased hunger
- skin rash
- swelling of front part of neck
- weight gain
Some ethionamide side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:More common
- Dizziness (especially when getting up from a lying or sitting position)
- loss of appetite
- metallic taste
- nausea or vomiting
- sore mouth
- Enlargement of the breasts (in males)
For Healthcare Professionals
Applies to ethionamide: oral tablet
Gastrointestinal side effects are the most common side effects of ethionamide (the active ingredient contained in Trecator-SC) and may be dose-related. They have included nausea, vomiting, diarrhea, abdominal pain excessive salivation, metallic taste, stomatitis, anorexia, and weight loss. Approximately one-half of patients cannot tolerate 1 gram as a single dose.
Nervous system side effects have included psychotic disturbances, mental depression, drowsiness, dizziness, restlessness, headache, peripheral neuritis, and a pellagra-like syndrome. Concomitant pyridoxine has been recommended to prevent or relieve neurotoxic effects.
Ocular side effects have rarely included optic neuritis, diplopia, and blurred vision.
Hepatic side effects have included transient increases in serum bilirubin, SGOT, SGPT, and hepatitis with or without jaundice.
Hypersensitivity reactions have rarely included rash, photosensitivity, thrombocytopenia, and purpura.
Metabolic side effects have included hypoglycemia and hypothyroidism.
Genitourinary side effects have included gynecomastia and impotence.
Dermatologic side effects have included rash and acne.
Hematologic side effects have included thrombocytopenia and purpura.
Cardiovascular side effects have included postural hypotension.
More about Trecator-SC (ethionamide)
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