Travel-Ease Side Effects

Generic Name: meclizine

Note: This page contains side effects data for the generic drug meclizine. It is possible that some of the dosage forms included below may not apply to the brand name Travel-Ease.

It is possible that some side effects of Travel-Ease may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to meclizine: oral capsule, oral tablet, oral tablet chewable

As well as its needed effects, meclizine (the active ingredient contained in Travel-Ease) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking meclizine, check with your doctor immediately:

Incidence not known
  • Cough
  • difficulty swallowing
  • dizziness
  • drowsiness
  • fast heartbeat
  • hives
  • itching
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • shortness of breath
  • skin rash
  • tightness in the chest
  • unusual tiredness or weakness

Some meclizine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Rare
  • Blurred vision
Incidence not known
  • Dry mouth
  • headache

For Healthcare Professionals

Applies to meclizine: compounding powder, oral tablet, oral tablet chewable

Nervous system

Nervous system (CNS) side effects have included headache, drowsiness and sedation. Motor skills may be impaired.[Ref]

With continued therapy, sedation due to meclizine diminishes.

An elderly woman suffered from memory loss, disorientation, paranoia, and agitation during treatment with meclizine over approximately 3 years. These symptoms returned on rechallenge.[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, dry mouth, and constipation.[Ref]

Ocular

Ocular side effects have included blurred vision, diplopia, and dry eyes.[Ref]

Genitourinary

Genitourinary side effects have included urinary retention and dysuria.[Ref]

Hypersensitivity

Anaphylactoid reactions have been reported.

Other

Fatigue has been reported.

References

1. Cohen B, deJong JM "Meclizine and placebo in treating vertigo of vestibular origin." Arch Neurol 27 (1972): 129-35

2. "Product Information. Antivert (meclizine)." Roerig Division, New York, NY.

3. Molloy DW "Memory loss, confusion, and disorientation in an elderly woman taking meclizine." J Am Geriatr Soc 35 (1987): 454-6

4. Manning C, Scandale L, Manning EJ, Gengo FM "Central nervous system effects of meclizine and dimenhydrinate: evidence of acute tolerance to antihistamines." J Clin Pharmacol 32 (1992): 996-1002

5. Wood CD, Manno JE, Manno BR, Redetzki HM, Wood MJ, Mims ME "Evaluation of antimotion sickness drug side effects on performance." Aviat Space Environ Med 56 (1985): 310-6

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