Drug Information
Side Effects > Tranylcypromine

Tranylcypromine Side Effects

Brand Names: Parnate

Please note - some side effects for Tranylcypromine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).


For the consumer

For the professional

Side Effects of Tranylcypromine - for the consumer


Tranylcypromine

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Tranylcypromine:

Blurred vision; constipation; diarrhea; drowsiness; dry mouth; stomach pain; tremors; upset stomach; weakness.

Seek medical attention right away if any of these SEVERE side effects occur when using Tranylcypromine:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation or anxiety; bizarre behavior; changes in heart rate; chest pain; difficulty sleeping; dilated pupils; dizziness; feelings of irritability and hostility; headache; impulsive behavior or other unusual changes in behavior; nausea; panic attacks; pounding in the chest; sensitivity to sunlight; severe nervousness or anxiety; severe restlessness; sleeplessness; sore or stiff neck; sweating (sometimes with fever or cold, clammy skin); thoughts of suicide; vomiting; worsening feelings of depression.

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For the professional


Tranylcypromine

Overstimulation which may include increased anxiety, agitation, and manic symptoms is usually evidence of excessive therapeutic action. Dosage should be reduced, or a phenothiazine tranquilizer should be administered concomitantly.

Patients may experience restlessness or insomnia; may notice some weakness, drowsiness, episodes of dizziness or dry mouth; or may report nausea, diarrhea, abdominal pain, or constipation. Most of these effects can be relieved by lowering the dosage or by giving suitable concomitant medication.

Tachycardia, significant anorexia, edema, palpitation, blurred vision, chills, and impotence have each been reported.

Headaches without blood pressure elevation have occurred.

Rare instances of hepatitis, skin rash, and alopecia have been reported.

Impaired water excretion compatible with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) has been reported.

Tinnitus, muscle spasm, tremors, myoclonic jerks, numbness, paresthesia, urinary retention, and retarded ejaculation have been reported.

Hematologic disorders including anemia, leukopenia, agranulocytosis, and thrombocytopenia have been reported.

Post-Introduction Reports

The following are spontaneously reported adverse events temporally associated with use of Tranylcypromine sulfate. No clear relationship between Tranylcypromine sulfate and these events has been established. Localized scleroderma, flare-up of cystic acne, ataxia, confusion, disorientation, memory loss, urinary frequency, urinary incontinence, urticaria, fissuring in corner of mouth, akinesia.

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More resources:

Cerner Multum tranylcypromine

PDR Parnate

MedFacts Tranylcypromine

Micromedex Tranylcypromine - Includes detailed dosage instructions.

FDA Tranylcypromine

FDA Parnate

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