Tranexamic acid Side Effects

Brand Names: Cyklokapron, Lysteda

Please note - some side effects for Tranexamic acid may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Tranexamic acid - for the Consumer

Tranexamic Acid

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Tranexamic Acid:

Back pain; headache; joint pain; muscle pain, spasms, or cramps; nasal or sinus congestion; stomach pain; tiredness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; flushing of the face); calf or leg pain, swelling, or tenderness; chest pain; confusion; coughing up blood; decreased urination or difficulty urinating; eye problems; fainting; numbness of an arm or leg; one-sided weakness; seizures; severe or persistent dizziness or light-headedness; shortness of breath; slurred speech; sudden, severe headache or vomiting; vision changes or problems (eg, disturbance of color vision, sharpness, or field of vision).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Tranexamic Acid Tablet

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Tranexamic Acid Tablet:

Diarrhea; giddiness; nausea; vomiting.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); calf pain, swelling, or tenderness; changes in vision (disturbance of color, sharpness, or field of vision); chest pain; decreased urination; one-sided weakness; severe headache; shortness of breath; speech problems.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Side Effects by Body System - for Healthcare Professionals

Gastrointestinal

Gastrointestinal side effects have frequently included nausea, vomiting, and diarrhea. Abdominal pain has also been reported.

Nervous system

Nervous system side effects have included giddiness, dizziness, headache, tension headache, and migraine.

Hematologic

Hematologic side effects have included thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism, cerebral thrombosis, acute renal cortical necrosis, and central retinal artery and vein obstruction) and anemia.

Hypersensitivity

Hypersensitivity side effects have included allergic skin reactions, anaphylactic shock and anaphylactoid reactions.

A case of severe allergic reaction to tranexamic acid was reported involving a subject on her fourth cycle of treatment who experienced dyspnea, tightening of her throat, and facial flushing that required emergency medical treatment.

Ocular

Ocular side effects have rarely included disturbances of color vision and retinal artery occlusion.

Musculoskeletal

Musculoskeletal side effects have included back pain, musculoskeletal pain, muscle cramps and spasms, myalgia, and arthralgia including joint stiffness and swelling.

Respiratory

Respiratory side effects have included nasal and sinus symptoms including nasal, respiratory tract and sinus congestion, sinusitis, acute sinusitis, sinus headache, and allergic sinusitis and sinus pain.

Cardiovascular

Cardiovascular side effects have included hypotension when intravenous administration exceeded 1 mL per minute.

Genitourinary

Genitourinary side effects have included ureteral obstruction due to clot formation in patients with upper urinary tract bleeding.

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