Thymoglobulin Side Effects

Generic Name: anti-thymocyte globulin (rabbit)

Note: This page contains side effects data for the generic drug anti-thymocyte globulin (rabbit). It is possible that some of the dosage forms included below may not apply to the brand name Thymoglobulin.

It is possible that some side effects of Thymoglobulin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to anti-thymocyte globulin (rabbit): intravenous powder for solution

As well as its needed effects, anti-thymocyte globulin (rabbit) may cause unwanted side effects that require medical attention.

Because of the way that anti-thymocyte globulin (rabbit) acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphomas and skin cancers. Discuss these possible effects with your doctor.

Although not all of these side effects may occur, if they do occur they may need medical attention.

If any of the following side effects occur while taking anti-thymocyte globulin (rabbit), check with your doctor or nurse as soon as possible:

More common
  • Black, tarry stools
  • bladder pain
  • chest pain
  • chills
  • cloudy or bloody urine
  • cold
  • confusion
  • cough or hoarseness
  • fast heartbeat
  • fever
  • flu-like symptoms
  • frequent urge to urinate
  • high blood pressure
  • irregular or slow heartbeat
  • lower back or side pain
  • numbness or tingling around lips hands, or feet
  • painful or difficult urination
  • shortness of breath or troubled breathing
  • sore throat
  • sores, ulcers, or white spots on lips or in mouth
  • swollen glands
  • tiredness or weakness
  • unexplained anxiety
  • unusual bleeding or bruising
  • weakness or heaviness of legs
Less common
  • Burning or stinging of skin
  • painful cold sores or blisters on lips, nose, eyes, or genitals

Some anti-thymocyte globulin (rabbit) side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Abdominal pain
  • diarrhea
  • difficult or labored breathing
  • dizziness
  • general feeling of discomfort or illness
  • headache
  • loss of strength or energy
  • muscle pain or weakness
  • nausea
  • pain
  • swelling of ankles, feet, and fingers
  • tightness in chest
  • unusual weak feeling
  • wheezing
Less common
  • White patches on mouth, tongue, or throat

For Healthcare Professionals

Applies to anti-thymocyte globulin (rabbit): intravenous powder for injection

General

General side effects have included chills, fever, infections and pain.[Ref]

Cardiovascular

Cardiovascular side effects have included hypertension, peripheral edema, tachycardia, pulmonary edema and myocardial infarction.[Ref]

Other

Other side effects have included infections (bacterial, fungal, viral and protozoal), reactivation of infections (particularly cytomegalovirus [CMV]) and sepsis.[Ref]

Nervous system

Nervous system side effects have included headache, malaise, asthenia and dizziness.[Ref]

Hematologic

Hematologic side effects have included leukopenia and thrombocytopenia.[Ref]

Gastrointestinal

Gastrointestinal side effects have included gastrointestinal and oral moniliasis, abdominal pain, nausea, diarrhea and vomiting.[Ref]

Genitourinary

Genitourinary side effects have included urinary tract infection and vaginitis.[Ref]

Dermatologic

Dermatologic side effects have included herpes simplex infections and rash.[Ref]

Respiratory

Respiratory side effects have included pneumonia, acute respiratory distress syndrome, pulmonary edema and dyspnea.[Ref]

Metabolic

Metabolic side effects have included hyperkalemia.[Ref]

References

1. "Product Information. Thymoglobulin (anti-thymocyte globulin (rabbit))." Genzyme Corporation, Cambridge, MA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Hide
(web1)