Symlin Side Effects

Generic name: pramlintide

Note: This document contains side effect information about pramlintide. Some of the dosage forms listed on this page may not apply to the brand name Symlin.

Some side effects of Symlin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to pramlintide: subcutaneous solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking pramlintide (the active ingredient contained in Symlin) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• severe nausea that lasts for 3 to 7 days; or

• more frequent high blood sugar levels.

Less serious side effects of pramlintide may include:

• runny or stuffy nose, sore throat, cough;

• nausea, loss of appetite;

• headache, tired feeling; or

• joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to pramlintide: subcutaneous solution

Metabolic

Metabolic side effects have included hypoglycemia. Severe hypoglycemia (requiring assistance in ingestion of oral carbohydrate, administration of glucagon, intravenous glucose, or other medical intervention) was reported in up to 8.2% of patients in long-term studies.

Gastrointestinal

Gastrointestinal side effects have included nausea, anorexia, vomiting, and abdominal pain.

Nervous system

Nervous system side effects have included headache and dizziness.

Musculoskeletal

Musculoskeletal side effects have included arthralgia and fatigue.

Respiratory

Respiratory side effects have included cough and pharyngitis.

Hypersensitivity

Hypersensitivity side effects have included allergic reactions.

General

General side effects have included injury.

Local

Local side effects have included post marketing reports of injection site reactions.

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