Surfaxin Side Effects

Generic name: lucinactant

Note: This document contains side effect information about lucinactant. Some of the dosage forms listed on this page may not apply to the brand name Surfaxin.

Some side effects of Surfaxin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to lucinactant: intratracheal suspension

Lucinactant causes few side effects. There is a possibility that the baby will have breathing difficulties during the lucinactant (the active ingredient contained in Surfaxin) treatment, and these problems may require further treatment by health care professionals. Your baby will remain under constant supervision during treatment with lucinactant.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to lucinactant: intratracheal suspension

Cardiovascular

Cardiovascular side effects have included patent ductus arteriosus (43%), hypotension (at least 10%) and bradycardia (at least 10%).

Gastrointestinal

Gastrointestinal side effects have included necrotizing enterocolitis (13%).

General

General side effects have included pallor (up to 10%).

Hematologic

Hematologic side effects have included anemia (at least 10%).

Hepatic

Hepatic side effects have included jaundice (at least 10%).

Immunologic

Immunologic side effects have included acquired sepsis (up to 45%).

Metabolic

Metabolic side effects have included metabolic acidosis (at least 10%), oxygen desaturation (at least 10%), hyperglycemia (at least 10%), hyponatremia (at least 10%), and respiratory acidosis (at least 10%).

Nervous system

Nervous system side effects have included intraventricular hemorrhage (up to 52%), and periventricular leukomalacia (up to 10%).

Ocular

Ocular side effects have included retinopathy of prematurity (up to 32%).

Respiratory

Respiratory side effects have included apnea (up to 66%), endotracheal tube reflux (up to 27%), pulmonary air leak (up to 15%), pneumonia (at least 10%), pulmonary hemorrhage (up to 10%), and endotracheal tube obstruction (up to 6%).

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