Suprane Side Effects
Generic name: desflurane
Medically reviewed by Drugs.com. Last updated on Sep 24, 2023.
Note: This document contains side effect information about desflurane. Some dosage forms listed on this page may not apply to the brand name Suprane.
Applies to desflurane: inhalation liquid, inhalation solution.
Serious side effects of Suprane
Along with its needed effects, desflurane (the active ingredient contained in Suprane) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking desflurane:
More common
- Bluish lips or skin
- body aches or pain
- chest tightness
- congestion
- cough
- dryness or soreness of the throat
- fever
- hoarseness
- not breathing
- runny nose
- tender, swollen glands in the neck
- trouble breathing
- trouble swallowing
- voice changes
Less common
- Blurred vision
- chest pain or discomfort
- dizziness
- fast, pounding, or irregular heartbeat or pulse
- headache
- lightheadedness, dizziness, or fainting
- nervousness
- pounding in the ears
- slow or irregular heartbeat
- unusual tiredness
Rare
- Dark urine
- difficulty with moving
- feeling of warmth or heat
- flushing or redness of the skin, especially on the face and neck
- general tiredness and weakness
- joint pain
- light-colored stools
- muscle aching or cramping
- muscle pains or stiffness
- nausea and vomiting
- noisy breathing
- pain or discomfort in the arms, jaw, back, or neck
- sweating
- swollen joints
- upper right abdominal or stomach pain
- yellow eyes and skin
Incidence not known
- Confusion
- decreased urine
- dry mouth
- increased thirst
- loss of appetite
- no blood pressure or pulse
- numbness or tingling in the hands, feet, or lips
- seizures
- stomach pain
- stopping of heart
- unconsciousness
- weakness or heaviness of the legs
Other side effects of Suprane
Some side effects of desflurane may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
- Increased watering of the mouth
- redness of the white part of the eyes or inside of the eyelids
Rare
- Anxiety
- irritability
- itching skin
- restlessness
- shaking
- trouble sleeping
For Healthcare Professionals
Applies to desflurane: inhalation liquid.
Respiratory
Very common (10% or more): Breath holding (27% in adults; 68% in pediatrics), laryngospasm (50% in pediatrics), cough (34%), apnea (15%)
Common (1% to 10%): Pharyngitis, apnea, cough, laryngospasm
Uncommon (0.1% to 1%): Hypoxia
Frequency not reported: Respiratory arrest, respiratory failure, respiratory distress, bronchospasm, hemoptysis[Ref]
Gastrointestinal
Very common (10% or more): Nausea (27%), salivary hypersecretion (21%), vomiting
Frequency not reported: Acute pancreatitis, abdominal pain[Ref]
Cardiovascular
Common (1% to 10%): Nodal arrhythmia, bradycardia, tachycardia, hypertension
Uncommon (0.1% to 1%): Myocardial infarction, myocardial ischemia, arrhythmia, vasodilation, ECG abnormal, electrocardiogram ST-T change, electrocardiogram T wave inversion
Frequency not reported: Cardiac arrest, torsade de pointes, ventricular failure, ventricular hypokinesia, malignant hypertension, hemorrhage, hypotension, shock, tachyarrhythmia, palpitations[Ref]
Nervous system
Common (1% to 10%): Headache
Uncommon (0.1% to 1%): Dizziness
Frequency not reported: Seizures, encephalopathy[Ref]
Hepatic
Frequency not reported: Hepatic necrosis, cytolytic hepatitis, cholestasis, jaundice, hepatic function abnormal, liver disorder, alanine aminotransferase increased, aspartate aminotransferase increased[Ref]
Ocular
Common (1% to 10%): Conjunctivitis
Frequency not reported: Ocular icterus, eye burns, transient blindness, ulcerative keratitis, ocular hyperemia, reduced visual acuity, eye irritation, eye pain[Ref]
Metabolic
Frequency not reported: Hyperkalemia, hypokalemia, metabolic acidosis, ammonia increased[Ref]
Musculoskeletal
Uncommon (0.1% to 1%): Myalgia
Frequency not reported: Rhabdomyolysis[Ref]
Dermatologic
Frequency not reported: Urticaria, erythema, skin burning sensation[Ref]
Hematologic
Frequency not reported: Coagulopathy, coagulation test abnormal[Ref]
Psychiatric
Uncommon (0.1% to 1%): Agitation[Ref]
Other
Common (1% to 10%): Increased creatinine phosphokinase
Frequency not reported: Malignant hyperthermia, asthenia, malaise, migraine, fatigue[Ref]
More about Suprane (desflurane)
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References
1. Product Information. Suprane (desflurane). Baxter Pharmaceutical Products, Inc. 2008.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.