Sumatriptan and naproxen Side Effects

Please note - some side effects for Sumatriptan and naproxen may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Applies to: oral tablet

Nervous system

Nervous system side effects including dizziness (4%), somnolence (3%), and paresthesia have been reported. Burning sensation, disturbance of attention, insomnia, mental impairment, and tremor have been reported infrequently. Aphasia, facial palsy, impairment of psychomotor skills, and sedation have been reported rarely.

Gastrointestinal

Gastrointestinal side effects including nausea (3%), dyspepsia (2%), and dry mouth (2%) have been reported. Abdominal pain has been reported frequently. Abdominal distention, constipation, diarrhea, dysgeusia, dysphagia, flatulence, gastritis, gastroesophageal reflux disease, and vomiting have been reported infrequently. Colitis, diverticulitis, gastric ulcer, irritable bowel syndrome, oral mucosal blistering, and swollen tongue have been reported rarely.

Other

Other side effects including chest discomfort/chest pain (3%) and neck/throat/jaw pain/tightness/pressure (3%) have been reported. Flushing, hot flushes, ear pain, and tinnitus have been reported infrequently. Pneumonia, sepsis, staphylococcal infection, epistaxis, peripheral coldness, motion sickness, and vertigo have been reported rarely.

General

General side effects including fatigue have been reported frequently. Feeling jittery, lethargy, malaise, peripheral edema, pyrexia, temperature intolerance, and thirst has been reported infrequently. Difficulty in walking has been reported rarely.

Hematologic

Hematologic side effects including lymphadenopathy, anemia, ecchymosis, and leukopenia have been reported infrequently.

Ocular

Ocular side effects including conjunctivitis have been reported infrequently. Cataract, conjunctival hemorrhage, and visual disturbance have been reported rarely.

Psychiatric

Psychiatric side effects including anxiety, depression, irritability, and nervousness have been reported infrequently. Disorientation and panic attack have been reported rarely.

Renal

Renal side effects including nephrolithiasis have been reported infrequently. Renal insufficiency has been reported rarely.

Dermatologic

Dermatologic side effects including facial swelling, hyperhidrosis, pruritus, rash, and urticaria have been reported infrequently. Systemic lupus erythematosus has been reported rarely.

Cardiovascular

Cardiovascular side effects including tachycardia and hypertension have been reported infrequently. Acute coronary syndrome, cardiac flutter, congestive cardiac failure, right ventricular failure, viral myocarditis, and ventricular extrasystoles have been reported rarely.

Musculoskeletal

Musculoskeletal side effects including arthralgia, back pain, muscular weakness, myalgia, and a sensation of heaviness have been reported infrequently.

Respiratory

Respiratory side effects including asthma, cough, dyspnea, and oropharyngeal swelling have been reported infrequently. Pleurisy has been reported rarely.

Metabolic

Metabolic side effects including hypoglycemia and diabetes mellitus have been reported rarely.

Endocrine

Endocrine side effects including goiter and hypothyroidism have been reported rarely.

Hepatic

Hepatic side effects including biliary colic have been reported rarely.

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