Sulfacetamide and prednisolone ophthalmic Side Effects

Please note - some side effects for Sulfacetamide and prednisolone ophthalmic may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Applies to: ophthalmic ointment; ophthalmic solution; ophthalmic suspension

Hypersensitivity

Hypersensitivity reactions to sodium sulfacetamide have been reported rarely. A case of Stevens Johnson syndrome has been reported in a patient who had previously experienced a bullous drug reaction to an orally administered sulfonamide. A case of local hypersensitivity which progressed to a fatal syndrome resembling systemic lupus erythematosus has also been reported.

Ocular

Ocular side effects associated with the prednisolone component have included elevation of intraocular pressure with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing. Corticosteroid-containing preparations have been reported to cause acute anterior uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation, and ptosis. Bacterial, fungal, and viral secondary ocular infections, transient burning and stinging upon instillation, other minor symptoms of ocular irritation, and visual disturbance (blurry vision) have also been reported with the use of ocular corticosteroids.

Local irritation, stinging, and burning have been reported with the use of sodium sulfacetamide.

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