Sufentanil Side Effects

It is possible that some side effects of sufentanil may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to sufentanil: parenteral injection

Side effects include:

Respiratory depression, skeletal muscle rigidity (e.g., truncal muscles, neck, extremities).

For Healthcare Professionals

Applies to sufentanil: compounding powder, intravenous solution

Respiratory

Respiratory side effects including respiratory depression, apnea, and bronchospasm have been reported frequently.

Cardiovascular

Cardiovascular side effects including hypotension, hypertension, bradycardia, cardiac arrest, and arrhythmias have been reported infrequently.

Musculoskeletal

Musculoskeletal side effects including skeletal muscle rigidity, particularly of the truncal muscles, intraoperative muscle movement, and chest wall rigidity have been reported frequently.

Gastrointestinal

Gastrointestinal side effects including nausea and vomiting have been reported.

Genitourinary

Genitourinary side effects including urinary retention have been reported commonly.

Dermatologic

Dermatologic side effects including pruritus and erythema have been reported.

General

General side effects including chills and somnolence have been reported.

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