Sudafed PE Nasal Decongestant Side Effects

Generic name: phenylephrine

Note: This document contains side effect information about phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Sudafed PE Nasal Decongestant.

Some side effects of Sudafed PE Nasal Decongestant may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to phenylephrine: oral disintegrating strip, oral liquid, oral suspension extended release, oral tablet, oral tablet chewable, oral tablet chewable extended release, oral tablet disintegrating

Get emergency medical help if you have any of these signs of an allergic reaction while taking phenylephrine (the active ingredient contained in Sudafed PE Nasal Decongestant) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using phenylephrine and call your doctor at once if you have a serious side effect such as:

• fast, pounding, or uneven heartbeat;

• severe dizziness or anxiety;

• easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

• dangerously high blood pressure (severe headache, blurred vision, ringing in your ears, anxiety, confusion, chest pain, trouble breathing, uneven heart rate, seizure).

Less serious side effects of phenylephrine may include:

• loss of appetite;

• warmth, tingling, or redness under your skin;

• feeling restless or excited (especially in children);

• sleep problems (insomnia); or

• skin rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to phenylephrine: compounding powder, injectable solution, intravenous solution, oral disintegrating strip, oral liquid, oral suspension extended release, oral tablet, oral tablet chewable, oral tablet chewable extended release, oral tablet disintegrating

Nervous system

Nervous system side effects have included headache, dizziness, nervousness, restlessness, tremor, insomnia, convulsions, and central nervous system depression.

Cardiovascular

Cardiovascular side effects have included palpitations, arrhythmias, and cardiovascular collapse with hypotension.

Psychiatric

Psychiatric side effects have included hallucinations, fear, and anxiety.

Gastrointestinal

Gastrointestinal side effects have included nausea.

Respiratory

Respiratory side effects have included respiratory difficulty.

Genitourinary

Genitourinary side effects have included dysuria.

General

General side effects have included pallor and weakness.