Sudafed PE Nasal Decongestant Side Effects

Generic Name: phenylephrine

Note: This page contains side effects data for the generic drug phenylephrine. It is possible that some of the dosage forms included below may not apply to the brand name Sudafed PE Nasal Decongestant.

It is possible that some side effects of Sudafed PE Nasal Decongestant may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to phenylephrine: intravenous solution

As well as its needed effects, phenylephrine (the active ingredient contained in Sudafed PE Nasal Decongestant) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking phenylephrine, check with your doctor or nurse immediately:

Incidence not known
  • Blurred vision
  • chest pain or discomfort
  • difficult or labored breathing
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • headache
  • nausea or vomiting
  • nervousness
  • pain in the shoulders, arms, jaw, or neck
  • pounding in the ears
  • sweating
  • tightness in the chest
  • unusual tiredness

If any of the following symptoms of overdose occur while taking phenylephrine, get emergency help immediately:

Symptoms of overdose
  • Feeling of fullness in the head
  • pounding or rapid pulse
  • tingling in the arms or legs
  • vomiting

Some phenylephrine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known
  • Heartburn
  • itching skin
  • nausea
  • pain in the neck
  • pain or discomfort in chest, upper stomach, or throat

For Healthcare Professionals

Applies to phenylephrine: compounding powder, injectable solution, intravenous solution, oral disintegrating strip, oral liquid, oral suspension extended release, oral tablet, oral tablet chewable, oral tablet chewable extended release, oral tablet disintegrating

Nervous system

Nervous system side effects have included headache, dizziness, nervousness, restlessness, tremor, insomnia, convulsions, and central nervous system depression.

Cardiovascular

Cardiovascular side effects have included palpitations, arrhythmias, and cardiovascular collapse with hypotension.

Psychiatric

Psychiatric side effects have included hallucinations, fear, and anxiety.

Gastrointestinal

Gastrointestinal side effects have included nausea.

Respiratory

Respiratory side effects have included respiratory difficulty.

Genitourinary

Genitourinary side effects have included dysuria.

General

General side effects have included pallor and weakness.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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